mer Allele Binding energy in Δ G kcal mol 1 Server Conservancy Karp 36AKVGVVGGMITGVES50 HLADQA10501DQB10301 79 12 4688 ScaA 84PGFRAEIGVMYLTNI98 HLADPA10103DPB10401 ID: 934169
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Slide1
ProteinMHC II Epitope (15 mer)AlleleBinding energy in ΔG (kcal mol-1)ServerConservancy (%)Karp36-AKVGVVGGMITGVES-50HLA-DQA1*05:01/DQB1*03:01 -7.91,246.88ScaA84-PGFRAEIGVMYLTNI-98HLA-DPA1*01:03/DPB1*04:01HLA-DPA1*02:01/DPB1*14:01HLA-DRB3*01:01HLA-DRB3*02:02-10.2-7.9-12.6-9.722.27169-LNDEQRAAARIAWLK-183HLA-DPA1*02:01/DPB1*14:01-11.7121.25205-NPILLNIPQGNPNPV-219HLA-DRB3*02:02-7111.25346-QGQQQQAQATAQEAV-360HLA-DQA1*03:01/DQB1*03:02HLA-DQA1*01:02/DQB1*06:02HLA-DQA1*04:01/DQB1*04:02-9.2-9.2-12.91,243.75356-AQEAVAAAAVRLLNG-370HLA-DPA1*02:01/DPB1*14:01HLA-DQA1*01:02/DQB1*06:02HLA-DQA1*04:01/DQB1*04:02HLA-DQA1*05:01/DQB1*03:01-9-7.8-9.5-10.11,245.62491-AINAAEGVYVDIEGS-505HLA-DQA1*05:01/DQB1*02:01HLA-DQA1*03:01/DQB1*03:02-9.5-12.5126.88518-SINPLMASVSVRYNF-532HLA-DPA1*02:01/DPB1*14:01HLA-DQA1*01:02/DQB1*06:02HLA-DRB1*03:01HLA-DRB1*07:01 HLA-DRB1*09:01 HLA-DRB1*12:01HLA-DRB1*13:02HLA-DRB3*02:02-8-10.5-8.6-6.7-9.7-10.8-11.6-1022.27Kato37-AKVGVVGGMITGVES-51HLA-DQA1*05:01/DQB1*03:01 7.9146.88135-IMPISIADRDLGVDI-149HLA-DRB4*01:01HLA-DRB1*03:01-9.1-8.91,25.62341-QQAQATAQEAAAAAA-355 HLA-DQA1*0102/DQB1*0602 -9.31,210.62347-AQEAAAAAAVRVLNN-361HLA-DQA1*05:01/DQB1*02:01HLA-DQA1*05:01/DQB1*03:01HLA-DQA1*04:01/DQB1*04:02HLA-DQA1*01:02/DQB1*06:02HLA-DPA1*02:01/DPB1*14:01-8.6-9.6-10.2-9.2-11.41,210.62SFSIYAGLGAGLAYTHLA-DQA1*05:01/DQB1*03:01HLA-DRB1*01:01HLA-DRB1*09:01HLA-DRB1*15:01-11.9-12.7-14.9-13.8227.27% (24/88)SGALGVAINAAEGVYHLA-DRB1*13:02HLA-DRB3*02:02HLA-DQA1*01:02/DQB1*06:02-11.3-9.5-7.2170.00% (112/160)
Table 4
Slide2ProteinMHC II Epitope (15 mer)AlleleBinding energy in ΔG (kcal mol-1)ServerConservancy analysis IEDB toolKato488-AINAAEGVYVDIEGS-502HLA-DQA1*05:01/DQB1*02:01HLA-DQA1*03:01/DQB1*03:02HLA-DQA1*04:01/DQB1*04:02-9.5-12.5-11.9126.88% (43/160)ScaA513-KYSINPLMASFGVRY-527HLA-DPA1*02:01/DPB1*14:01HLA-DRB1*09:01HLA-DRB1*12:01HLA-DRB1*13:02HLA-DRB1*15:01HLA-DRB3*02:02-13.2-13.5-9.9-8-11.4-9.5213.64% (12/88)Gilliam152-GVDTDILAQAAAGQP-166HLA-DQA10301DQB10302HLA-DRB40101-13.2-7.8117.50% (28/160)338-QGQQQQAQATAQEAV-352HLA-DQA10102DQB10602HLA-DQA10301DQB10302-9.8-13143.75% (70/160)348-AQEAVAAAAVRLLNG-362HLA-DQA10501-DQB10301DRB10901 HLA-DPA10201DPB11401HLA-DQA10102DQB10602HLA-DQA10401DQB10402 HLA-DR1-10.1-10.6-9-8.5-9.5-11.61,245.62% (73/160)444-ESFSIYAGVGAGLAH-458HLA-DRB10901HLA-DRB11501-15.1-11.619.38% (15/160)477-SGALGVAINAAEGVY-491HLA-DRB1*13:02HLA-DRB3*02:02HLA-DQA1*01:02/DQB1*06:02-11.3-9.5-7.2170.00% (112/160)TA763323-ANQIQLNFVMPQQAQ-337DQA10501-DQB10301DRB1-0802DRB10901DRB11101DRB11201DRB11302DRB11501DRB30202DRB40101DRB50101HLA-DPA10201DPB10101HLA-DPA10301DPB10402HLA-DQA10101DQB10501HLA-DQA10102DQB10602HLA-DQA10501DQB10201HLA-DRB10101HLA-DRB10401HLA-DRB10405HLA-DRB10701HLA-DPA10103DPB10201-10.4-10.9-17.8-10.4-10.1-11.3-12.3-12.3-10.2-11.2-12.6-13.3-10.2-7.9-11.7-10.9-7.5-10.9-16-13.51,226.88% (43/160)Table 4
Slide3ProteinMHC II Epitope (15 mer)AlleleBinding energy in ΔG (kcal mol-1)ServerConservancy analysis IEDB tool342-GQQQQAQATAQEAVA-356HLA-DQA10102DQB10602HLA-DQA10401DQB10402HLA-DQA10501DQB10301-10.7-10.9-11.11,244.38% (71/160)ScaA448-SVSIYAGVGAGLAYT-462DQA10501-DQB10301DRB10901DRB11501HLA-DRB10101-11.8-15.9-10.7-9.61,25.62% (9/160)TA716113-DTRADTDSPILQRPK-127HLA-DQA10501DQB10201-9.112.50% (4/160)340-QQAQATAQEAAAAAA-354 HLA-DQA1*0102/DQB1*0602 -9.3110.62% (17/160)176-LKDYAGIEYMVKDPN-200HLA-DPA1*0201/DPB1*0501-6.611.25% (2/160)ScaA236-QNEGYGVQKVIIKQD-250DQA10501-DQB10301HLA-DQA10102DQB10602HLA-DQA10301DQB10302HLA-DQA10401DQB10402HLA-DQA10501DQB10201HLA-DR1-12.8-9.2-12.6-10.8-11.1-1019.09% (1/11)255-DKIEGRSASIEMSIE--269DQA10501-DQB10301HLA-DQA10102DQB10602HLA-DQA10301DQB10302HLA-DQA10401DQB10402HLA-DQA10501DQB10201HLA-DR1-12.8-9.2-12.6-10.8-11.1-1029.09% (1/11)1194-VAAISSIVQSRASNS-1208DQA10501-DQB1030DRB1-0802DRB10901 DRB11101DRB11201DRB11302DRB11501DRB30202DRB40101DRB50101HLA-DQA10102DQB10602 HLA-DR1HLA-DRB10401HLA-DRB10405HLA-DRB10701-15.6-11.4-14.6-10.3-12-11.3-9-9.8-10.4-10-8.3-10.8-9.9-9.8-7.529.09% (1/11)Table 4