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The Relapse Patterns of Adjuvant Radiotherapy in The Relapse Patterns of Adjuvant Radiotherapy in

The Relapse Patterns of Adjuvant Radiotherapy in - PowerPoint Presentation

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The Relapse Patterns of Adjuvant Radiotherapy in - PPT Presentation

Childhood Ependymoma OBJECTIVES The purpose of this study is to evaluate the relapse patterns and prognostic factors related with survival after adjuvant radiotherapy  in childhood  ID: 932519

university relapse department patterns relapse university patterns department csi medicine faculty serra survival spinal kamer ependymoma radiotherapy median cases

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Slide1

The Relapse Patterns of Adjuvant Radiotherapy in

Childhood

Ependymoma

OBJECTIVES:

The purpose of this study is

to evaluate the relapse patterns and prognostic factors related with survival after adjuvant radiotherapy  in childhood ependymoma.

Serra Kamer, Beril Balcı, Mehmet Kantar, Eda Ataseven ,Elif Bolat , Tuncer Turhan, Yavuz AnacakEge University Faculty of Medicine Department of Radiation OncologyEge University Faculty of Medicine Department of Pediatric OncologyEge University Faculty of Medicine Department of Neurosurgery

MATERIALS AND METHODS:

Serra Kamer, MD

Ege

University Faculty of Medicine, Department of Radiation Oncology serra.kamer@ege.edu.tr

32 patients Median age: 6.5 y(2-16) F/M:1.13

01

/1993 - 01/2017

Tumor

localization; Posterior fossa 21(%65.6) , Supratentorial 8 (%25)Spinal 3 (%9.4).At time of diagnosis, spinal seeding  was detected in 8 cases (%25).

Radiotherapy

dose:CSI 36GyPosterior fossa 54GyLocal-spinal 45Gy, Supratentorial 54-59.4 Gy.

RESULTS: Mean follow-up : 42 months (range 1-312)Median overall survival : 96 months3-year overall and PFS were %70 and % 51.7Relapse was recorded after the median time of 16 months (range: 5-132) in 16 cases (50%).There was no significant difference between relapse patterns and sites between two groups (local RT vs CSI) (p>0.5). Craniospinal relapse after radiotherapy was significantly associated with lower survival (p: 0.016).

CONCLUSION

S: Historically CSI was the standard treatment for ependymoma, however local RT provides the similar success compared to CSI and should be preferred.

Table: RT Site-Relapse Patterns Lokal Craniospinal TotalRT planLocalCraniospinalTotal731054912719