Childhood Ependymoma OBJECTIVES The purpose of this study is to evaluate the relapse patterns and prognostic factors related with survival after adjuvant radiotherapy in childhood ID: 932519
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The Relapse Patterns of Adjuvant Radiotherapy in
Childhood
Ependymoma
OBJECTIVES:
The purpose of this study is
to evaluate the relapse patterns and prognostic factors related with survival after adjuvant radiotherapy in childhood ependymoma.
Serra Kamer, Beril Balcı, Mehmet Kantar, Eda Ataseven ,Elif Bolat , Tuncer Turhan, Yavuz AnacakEge University Faculty of Medicine Department of Radiation OncologyEge University Faculty of Medicine Department of Pediatric OncologyEge University Faculty of Medicine Department of Neurosurgery
MATERIALS AND METHODS:
Serra Kamer, MD
Ege
University Faculty of Medicine, Department of Radiation Oncology serra.kamer@ege.edu.tr
32 patients Median age: 6.5 y(2-16) F/M:1.13
01
/1993 - 01/2017
Tumor
localization; Posterior fossa 21(%65.6) , Supratentorial 8 (%25)Spinal 3 (%9.4).At time of diagnosis, spinal seeding was detected in 8 cases (%25).
Radiotherapy
dose:CSI 36GyPosterior fossa 54GyLocal-spinal 45Gy, Supratentorial 54-59.4 Gy.
RESULTS: Mean follow-up : 42 months (range 1-312)Median overall survival : 96 months3-year overall and PFS were %70 and % 51.7Relapse was recorded after the median time of 16 months (range: 5-132) in 16 cases (50%).There was no significant difference between relapse patterns and sites between two groups (local RT vs CSI) (p>0.5). Craniospinal relapse after radiotherapy was significantly associated with lower survival (p: 0.016).
CONCLUSION
S: Historically CSI was the standard treatment for ependymoma, however local RT provides the similar success compared to CSI and should be preferred.
Table: RT Site-Relapse Patterns Lokal Craniospinal TotalRT planLocalCraniospinalTotal731054912719