Claire Donald MRCUniversity of Glasgow Centre for Virus Research 21 st May 2019 claireldonald CVRInfo Worldwide Spread World Health Organisation 2016 Uganda 1947 ID: 1047956
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1. Going Viral: Natural Selection of Infectious Diseases Claire Donald MRC-University of Glasgow Centre for Virus Research21st May 2019 @claireldonald @CVRInfo
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4. Worldwide Spread World Health Organisation, 2016Uganda, 1947Nigeria, 1954Yap, 2007Micronesia, 2009-2013South America, 2015
5. [Purdue University/Rossmann/Kuhn][PDP-101.rcsb.org]Virus Structures
6. Family Tree Family: FlaviviridaeGenus: Flavivirus
7. Transmission TRANSMISSIONMosquitoesPrimates ChimpanzeesMonkeysBaboons Humans
8. Anyone hungry? Credit: Choumet et al, 2012https://youtu.be/MbXSPacvuak
9. Alternative Transmission Routes MosquitoesMother to babySexualLab acquired Blood transfusion
10. Classical Symptoms
11. Further Complications Congenital Zika Syndrome: Severe microcephaly - the skull has collapsed Decreased brain tissue – brain damage Damage to the back of the eye Curved joints Rigid limbs Microcephalic Healthy
12. Further Complications Guillain-Barré Syndrome (GBS): Muscle weakness in the arms and legs due to immune system attacking the nervous systemGBS is strongly associated with ZIKV, however only a small proportion get GBS
13. Treatment Options No vaccine or treatment Protect yourself from mosquito bites Treat the symptomsRest and drink plenty of fluids to prevent dehydration
14. The Future of Zika Virus Vaccine development Surveillance ResearchMosquito Control
15. Thank you!