Medical Director PAS PROBLEM National Concern 60 Million Americans suffer from allergies 40 of children 30 of adults 90 of asthma is triggered by allergies Allergies increased 50 since 1997 ID: 651750
Download Presentation The PPT/PDF document "Introduction Michael T. Parra MD" is the property of its rightful owner. Permission is granted to download and print the materials on this web site for personal, non-commercial use only, and to display it on your personal computer provided you do not modify the materials and that you retain all copyright notices contained in the materials. By downloading content from our website, you accept the terms of this agreement.
Slide1
IntroductionMichael T. Parra MDMedical Director, PASSlide2
PROBLEM – National Concern60 Million Americans suffer from allergies
40% of children – 30% of adults
90% of asthma is triggered by allergies
Allergies increased 50% since 1997
Testing is traumatic and treatment is time consuming Slide3
RESULT – Mask SymptomsApproximately 95% of patients go untreated!
Americans spent $17.5 Billion in 2010*
($18B in 2015)
antihistamines, decongestants, inhalers, steroids
pills, eye drops, nasal sprays
Still suffer dreaded trips to the ERAsthma attacks during sporting events, etc.
* Schaffer F. National Impact of Allergies. Academy of Allergy and Asthma in Primary Care.
http://www.aaapc.us/wp-content/uploads/2013/01/National-Impact-of-Allergies.pdf
(Retrieved April 8 2015)Slide4
PROBLEM – Why? (Standard Testing) Scratch Tests
Painful – 40-50 skin pricks
Limited - only 40-50 allergens
Time consuming – 20-25 minutes
30% false positive results
Subjective – Observation alone
Non-measurable as a repeatable testSlide5
PROBLEM – Why? (Standard Testing) Intradermal Shots
Potential risks – insert food & other allergens
Subjective – Observation only
Non-measurableSlide6
PROBLEM – Why? (Standard Testing) Food Challenge
Potential risks – insert concentrated amount of food
Tragic Result
Alastair Watson – Children’s Hospital of AL – 07/30/17Slide7
PROBLEM – Why? (Standard Treatment)Weekly shots
(SCIT)
Time consuming
(missed school & work)
Children are afraid of shots
Titrate up 6-9 months to reach the maintenance levelDo not feel better for at least 9 months, 84% drop out rateSlide8
PROBLEM – Why? (Standard Treatment)Sublingual drops
(SLIT)
Hold under tongue for two minutes – forget to do
Unpleasant taste
Compliance 60%Slide9
NO NEW DEVELOPMENTS IN ALLERGY TESTING AND TREATMENT PROTOCOLS IN USA FOR 20 YEARS …UNTIL NOW!Slide10
SOLUTION – NEW IN-OFFICE TEST & TREATMENT PROGRAMNow you can test and treat your allergy patients in your office!
No longer need to refer over 95% of allergy patients to allergists
As simple as 1…2…3Slide11
STEP ONE – NEW TESTFinger-prick blood test – 120 allergens
(compared to 40-50 with scratch tests)
Unique Next-Generation Microarray Chip Assay
Most advanced – FDA cleared technology
Simply drop 4 drops on specialized paper
Airborne, environment & food50 Allergen non-inhalant panel
Foods, insects, latex, penicillin
70 Allergen environmental inhalant panel
Animals, fungi, grass, insects, molds, trees, weeds Slide12
Sensitivity and Specificity ResultsFINGER-PRICK BLOOD TEST
Allergy tests correctly scored 20 positive and negative serum specimens for a total of
1,160
analytes for
100%
sensitivity and
100%
specificity for the inhalant allergens.
Allergy tests correctly scored 20 positive and negative serum specimens for a total of
660
analytes for
100%
sensitivity and
100%
specificity for the non-inhalant allergens.Slide13
Studies – Asthma & FoodStudy of 215 children (1-14yrs) using
ImmunoCAP
Rapid testing demonstrated effective (88.4-97.6%) correct identification of allergic sensitization in children with recurrent asthma.
Prospective food allergy study of this technology demonstrating the importance of quantitative
IgE
measurements in 100 children, referred for food allergy evaluation tested for IgE to egg, milk, peanut, soy, wheat, and fish after dx of food allergy established on
hx
and food challenge. Results showed greater than 95% of food allergies were correctly identified, and could predict clinical reactivity
(positive food challenges)
with greater than 95% certainty.
Diaz-Vazquez C, et al. Accuracy of
ImmunoCAP
(R) rapid in the diagnosis of allergic sensitization in children between 1 and 14 years with recurrent wheezing: the
IReNE
study. Pediatric Allergy
Immunol
2009;20:601-9.
Sampson HA. Utility of food specific
IgE
concentration
s
in predicting symptomatic food allergy. J Allergy
Clin
Immunol
2001;107:891-6.
FINGER-PRICK BLOOD TESTSlide14
STEP ONE – NEW TESTFinger-Prick Blood Test
Safe, Fast & Easy
Four Drops of Blood
Measurable results
Comprehensive
120 Allergens vs 40-50 with Scratch Test
Eliminates need for Food Challenge – Safe!Slide15
Acremonium, Alder, Alfalfa Pollen, Alternaria, Aspergillus, Auareobasidum
, Australian Pine, Bahia grass, Bald cypress, Bayberry (wax myrtle), Bermuda grass, Birch White, Box Elder, California Live Oak, Candida
Albicans
, Cat Hair, Cattle Hair, Cedar Red, Cedar Mountain,
Cladosporium
, Cocklebur, Cockroach Mix, Cottonwood, Curvularia, Dog Hair, Drechslera
, Elm American, Elm Chinese, English
planain
,
Epicoccum
, Fusarium, Horse Hair, Johnson Grass, June Grass, Juniper, Kochia, Lamb's Quarters, Maple Pollen, Mite
Farinae
, Mite
Pteronyssinus
, Mouse Hair,
Mucor
Plumbeus
,
Mugwort
, Olive Russian, Pecan Pollen, Perennial Ryegrass,
Phoma
Herbarum
, Queen Palm, Rough Pigweed, Russian Thistle, Pine White, Poplar White, Privet, Queen Palm, Ragweed False, Ragweed Western, Red Birch, Red Mulberry, Red Oak, Rough Marsh Elder, Sagebrush, Shagbark Hickory, Sheep Sorrel, Short Ragweed, Sycamore American, Tall Ragweed, Timothy Grass, Virginia Live Oak, Walnut Black Pollen, White Ash, White Oak, Willow Black
Non-Inhalant and Environmental Allergens Slide16
Almond, Apple, Banana, Barley, Beef, Brazil Nut, Buckwheat, Casein, Carrot, Celery, Chicken, Clam, Cod Fish, Corn, Crab, Egg White, Egg Yolk, Flounder, Garlic, Green Pea, Halibut, Lobster, Milk, Mustard Seed, Oat, Oyster, Peach, Peanut, Pork, Rye, Salmon, Sesame Seed, Shrimp, Soybean, Strawberry, Tomato, Tuna, Walnut, Wheat, Yeast
Food AllergensSlide17
STEP TWO – PRESCRIBEWrite prescription for customized serum
Compounding pharmacy
Mixes unique allergen serum, based
on finger stick non-food allergen resultsSlide18
STEP THREE – TOOTHPASTEOral Mucosal Immunotherapy (OMIT)
Serum is mixed in OMIT base to create prescribed toothpaste
Patient returns quarterly for checkup and receive next 90-day supplySlide19
STEP THREE – NEW TOOTHPASTESafe - Natural
More effective than SCIT (shots) or SLIT (sublingual drops)
Begin at maintenance level
(vs. titrate up 6-9 months)
Patients feel better – faster
Increase complianceSlide20
BENEFITS – To PracticeSolve a national concern
Provide testing & treatment in office
Measurable Results
Natural, safe, effective regimen specifically designed for non-food allergies
New revenue:
Quarterly office visits
Admin fee with TreatmentSlide21
BENEFITS – To PatientNot Scary/Quick
- Prick finger
Safe
– Drop blood on card for testing
Effective
– Natural therapySimple – Brush teeth for 2 min
Tastes good
Berry or Mint flavorSlide22
BENEFITS – To Parents/PatientsSave Time
No weekly trips to allergist
No missed work or school
Save Money
Gas, parking fees, time
No copays ($20-$50 per visit)
Easy & sustainable treatment
Brush teeth daily for 2 minutesSlide23
SUMMARYUnique Microarray Chip Assay (Test)
Drop 4 Drops of blood on card
(safe/quick)
120 Allergens
(vs 40-50 with scratch testing)
Measurable results (from test to test)
Prescribe
Unique serum per patient
Toothpaste
Most effective delivery system
(start at maintenance level vs. titrating up 6-9 months like with shots)
Saves money ($120 for shots vs. $105)Slide24
RESULTReplace or enhance
out-dated
:
Scratch test
Intradermal test
Food ChallengeReplace weekly shots (time consuming)
Replace sublingual drops
(unpleasant taste)
Treat 95% of patients in office!
(currently untreated)
Feel better – sooner
Compliant – completion of regimenSlide25
LEARN MORE…Is this safe?
Does it work?
For more information, go to:
www.PediatricAllergySolutions.com