Nathan D Wong PhDa Dan Kouwabunpatb Anthony N Vo BS a Robert C Detrano MD PhDC Harvey Eisenberg MDd Mukesh Goel MDa and Jonathan M Tobis MD148 Irvine Newport Beach and Torrance ID: 941880
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Coronary calcium and atherosclerosis by ultrafast computed tomography in asymptomatic men and women: Relation to age and risk factors Nathan D. Wong, PhD,a Dan Kouwabunpat,b
Anthony N. Vo, BS, a Robert C. Detrano, MD, PhD,C Harvey Eisenberg, MD,d Mukesh Goel, MD,a and Jonathan M. Tobis, MD” Irvine, Newport Beach, and Torrance, Calif. Corona
ry heart disease (CHD) From the BDivision of Cardiology, Department of Medicine, University of California, Irvine; bPomona College; CThe St. Johns Cardiovascular Re- search
Institute, Harbor-University of California, Los Angeles, Medical Center; and dMultidimensional Imaging. Supported by the Medical Research and Education Society and the Amer-
ican Heart Association (Student Research Fellowship). Received for publication May 19, 1993; accepted July sensitivity for predicting advanced lesions. Among accident or oth
er noncoronary autopsy studies re- cently completed in young adults, CAC deposits have also been documented, demonstrating potential value as an early marker of CHD.12 Studie
s done in patients with symptoms show that METHODOLOGY Study population and interview. Our report includes all men and women self-referred (or referred by their 422 Volum
e 127, Number 2 American Heart Journal Wong et al. 423 Fig. 1. Patient positioned in Imatron C-100 Ultrafast CT scanner. physician) to a private medical clinic for ultrafas
t CT screening between May 1991 December 1992, usually as a result of known coronary risk factors or a family history of CHD and risk factors. All patients age 55 0, 1, 2, 3