I found out about my mutax00740069on six years ax00660074er m - PDF document

“I found out about my muta�on six years a�er my diagnosis of prostate cancer. People seem to think that only women are affected by gene muta�ons, but men are too. Knowledge and understanding can make a big difference.”–MIKE PHILBIN, BRCA2 Prostate Cancer Survivor HEREDITARY PROSTATE CANCERFORCE improves the lives of the millions of individuals and families facing hereditary cancer. Learn more at FacingOurRisk.org Genes with muta�ons linked to prostate cancer risk include:•A•BR•BRGene muta�ons linked to Lynch syndrome also elevate prostate cancer risk:Approximately with prostate cancer will have an inherited gene muta�on that caused their cancer. Experts recommend gene�c counseling and tes�ng for anyone who has high-grade or metasta�c prostate cancer or is diagnosed with prostate cancer before age 50.Experts may recommend tumor biomarker tes�ng for people with advanced prostate cancer to look for abnormali�es that may help guide cancer treatment.Gene�c tes�ng can determine your eligibility for specialized treatments and help you and your rela�ves manage cancer risk. What You Should Know Gene�c tes�ng is also recommended:•when tumor biomarker tes�ngsuggests an inherited muta�on•if a rela�ve has tested posi�ve for amuta�on linked to prostate cancer•for people of Eastern European(Ashkenazi) Jewish ancestry•EPCAM•MLH1•MSH2•MSH6•PMS2 •CHEK2•HOXB13•PALB2 •if a close relative has had one of these cancers:•if