Connective Tissue Maarefa PowerPoint Presentation, PPT - DocSlides

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Types of Connective Tissue:

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Slide1

Connective Tissue

Maarefa

College

Slide2

Objectives

What is connective tissue

Types of connective tissues

Functions of connective tissues

Relation of structure and function

Slide3

Tissues

Four fundamental tissues are recognized:

Epithelial tissue

Connective tissue

Muscular tissue

Nervous tissue

Slide4

Connective Tissue

Consists of two basic elements:

Cells, and

Extra-cellular matrix (abundant) (dominant part)

Fibers, and

Ground substance

liquid, gel, or solid

FunctionBind and/or support other tissue

Slide5

Connective Tissue

Consists of two basic elements:

Cells, and

Extra-cellular matrix (abundant) (dominant part)

Fibers, and

Ground substance

liquid, gel, or solid

FunctionBind and/or support other tissue

Slide6

Connective Tissue Cells

Fibroblasts:

Secrete both fibers and ground substance of the matrix (wandering)

Macrophages:

Phagocytes that develop from

Monocytes

(wandering or fixed)

Plasma Cells:Antibody secreting cells that develop from B-Lymphocytes (wandering)

Slide7

Connective Tissue Cells

Mast Cells

Produce histamine that help dilate small blood vessels in reaction to injury (wandering)

Adipocytes

:

Fat cells that store triglycerides, support, protect and insulate (fixed)

Slide8

Connective Tissue Cells

Slide9

Matrix Fibers

Collagen Fibers

Elastic Fibers

Reticular Fibers

Slide10

Matrix Fibers

Collagen Fibers:

Large fibers made of the protein collagen

The most abundant fibers

Promote tissue flexibility

Slide11

Matrix Fibers

Elastic Fibers:

Intermediate fibers made of the protein

Elastin

Branching fibers that allow for stretch and recoil

Polarizing microscopy

picrosirius

-stained collagen,

elastic fibers are stained by

orcein

Slide12

Matrix Fibers

Reticular Fibers:

Small delicate, branched fibers

Have same chemical composition of Collagen

Forms structural framework for organs such as spleen and lymph nodes.

Slide13

Matrix Fibers

Slide14

Matrix Fibers

Collagen

Elastin

Slide15

Elastic and Collagen Fibers

Slide16

Fibroblasts

Active fibroblasts have extensions

Extensions of fibroblasts (arrow-heads) are seen with the cell or alone, depending on section plane

Slide17

Fibroblasts

Active fibroblasts have extensions

Electron micrograph of fibrocyte with cytoplasmic extensions

interdigitating

among collagen fibers, X 26,000

Slide18

Matrix Ground Substance

Hyaluronic

Acid:

Complex combination of polysaccharides and proteins found in “true” or proper connective tissue

Chondriotin

sulfate:

Jellylike ground substance of cartilage, bone, skin and blood vessels

Other ground Substances: Dermatin sulfate, keratin sulfate, and adhesion proteins

Slide19

Types of Connective Tissue

True (Proper) Connective Tissue

Loose Connective Tissue

Dense Connective Tissue

Supportive Connective Tissue

Cartilage

Bone

Liquid Connective Tissue

Blood

Slide20

True or Proper Connective Tissue

Loose Connective Tissue:

Areolar tissue

Widely distributed under epithelia

Adipose tissue

Hypodermis, within abdomen, breasts

Reticular connective tissue

Lymphoid organs such as lymph nodes

Slide21

Loose Connective Tissue

Areolar

CT

consists of all 3 types of fibers, several types of cells, and semi-fluid ground substance

found in subcutaneous layer and mucous membranes, and around blood vessels, nerves and organs

function = strength, support and elasticity

Slide22

Loose Connective Tissue

Areolar

CT

Slide23

Loose Connective Tissue:

Adipose tissue

consists of

adipocytes

; "signet ring" appearing fat cells. They store energy in the form of triglycerides (lipids)

found in subcutaneous layer, around organs and in the yellow marrow of long bones

function = supports, protects and insulates, and serves as an energy reserve

Slide24

Loose Connective Tissue:

Adipose tissue

Slide25

Loose Connective Tissue

Adipose tissue

Slide26

Slide27

Loose Connective Tissue

Reticular CT

Consists of fine interlacing reticular fibers and reticular cells

Found in liver, spleen and lymph nodes

Function = forms the framework (

stroma

) of organs and binds together smooth muscle tissue cells

Slide28

Loose Connective Tissue

Reticular CT

Slide29

Loose Connective Tissue

Reticular CT

Slide30

Loose Connective Tissue

Reticular CT

Slide31

Loose Connective Tissue

Reticular CT

Slide32

True (Proper) Connective Tissue

Contains more numerous and thicker fibers and far fewer cells than loose CT

Dense Connective Tissue:

Dense regular connective tissue

Tendons and ligaments

Dense irregular connective tissue

Dermis of skin,

submucosa of digestive tract

Slide33

True (Proper) Connective Tissue

Dense regular Connective Tissue

consists of bundles of collagen fibers and fibroblasts

forms tendons, ligaments and

aponeuroses

Function = provide strong attachment between various structures

Slide34

True (Proper) Connective Tissue

Dense regular Connective Tissue

Slide35

True (Proper) Connective Tissue

Dense regular Connective Tissue

Slide36

True (Proper) Connective Tissue

Dense regular Connective Tissue (Tendon)

Slide37

True (Proper) Connective Tissue

Dense Irregular CT

Consists of randomly-arranged collagen fibers and a few fibroblasts

Found in fasciae, dermis of skin, joint capsules, and heart valves

Function = provides strength

Slide38

True (Proper) Connective Tissue

Dense Irregular CT

Slide39

Supportive Connective Tissue:

Cartilage:

Jelly-like matrix (

chondroitin

sulfate) containing collagen and elastic fibers and

chondrocytes

surrounded by a membrane called the

perichondriumUnlike other CT, cartilage has NO blood vessels or nerves except in the perichondrium

Collagen fibers provide strengthchondroitin sulfate provides resilienceChondrocytes occur within spaces in the matrix called lacunae.

Slide40

Supportive Connective Tissue

Cartilage:

Hyaline cartilage

Fibro-cartilage

Elastic cartilage

Slide41

Supportive Connective Tissue

Hyaline Cartilage (most abundant type)

Fine collagen fibers embedded in a gel-type matrix

Occasional

chondrocytes

inside lacunae.

Found in:

embryonic skeleton,at the ends of long bones (joints),in the nose and in respiratory structures

Function= flexible, provides support, allows movement at joints

Slide42

Supportive Connective Tissue

Hyaline Cartilage (most abundant type)

Slide43

Supportive Connective Tissue

Hyaline Cartilage (most abundant type)

Slide44

Supportive Connective Tissue

Hyaline Cartilage (most abundant type)

Perichondrium

Perichondrium

Hayaline

Cartilage

Slide45

Supportive Connective Tissue

Hyaline Cartilage (most abundant type)

Covers

articular

surfaces

Slide46

Supportive Connective Tissue

Fibrocartilage

contains bundles of collagen in the matrix that are usually more visible under microscopy

Found in:

Intervertebral

discs,

Menisci of the knee,

Pubic Symphysis

,Tendon insertion on apophyseal hyaline cartilageFunction:

Support and fusion, shock absorption

Slide47

Supportive Connective Tissue

Fibrocartilage

Slide48

Supportive Connective Tissue

Fibrocartilage

Slide49

Supportive Connective Tissue

Fibrocartilage

Slide50

Supportive Connective Tissue

Fibrocartilage

Picrosirius-Hematoxilin

stain of

fibrocartilage

, with abundant collagen fibers

Slide51

Supportive Connective Tissue

Elastic Cartilage

Threadlike network of elastic fibers within the matrix

Found in:

external ear,

auditory tubes,

epiglottis

function = gives support, maintains shape, allows flexibility

Slide52

Supportive Connective Tissue

Elastic Cartilage

Slide53

Supportive Connective Tissue

Elastic Cartilage

Slide54

Supportive Connective Tissue

Elastic Cartilage

Resorcin

stain selectively staining the elastic fibers of elastic cartilage tissue

Cells are not stained

Slide55

Supportive Connective Tissue

Bone

The hardest CT

Osteocytes in small cavities- lacunae

Impregnated

w

/ calcium salts

Types:Spongy (cancellous)Loose rods of bones

Found inside body of long bones, and ends of arms and legsCompact (cortical)Tightly organizedFound

inshafts

of long bones

Slide56

Supportive Connective Tissue

Bone Types:

Spongy (

cancellous

)

Loose rods of bones

Found inside body of bones, and ends of arms and legs

Compact (cortical)Tightly organizedFound in shafts of long bones

Slide57

Supportive Connective Tissue

Bone

Slide58

Supportive Connective Tissue

Bone

Slide59

Supportive Connective Tissue

Bone

Section of a

Haversian

system (

Osteone

)

Slide60

Supportive Connective Tissue

Bone cells

Osteoclasts

:

resorb

(eat) bone

Slide61

Supportive Connective Tissue

Bone cells

Osteoclasts

:

resorb

(eat) bone

Osteoblasts

:build boneOsteocytes:

osteoblasts surrounded by matrix they formed

Slide62

Supportive Connective Tissue

Bone cells

Osteoclasts

:

resorb

(eat) bone

Osteoblasts

: build boneOsteocytes: mature osteoblasts surrounded by matrix that it formed

Slide63

Liquid Connective Tissue

Blood

Slide64

Liquid Connective Tissue

Lymph

Slide65

Summary

What is connective tissue

Structure: Consists of two basic elements:

Cells, and

Extra-cellular matrix (abundant) (dominant part)

Fibers, and

Ground substance (liquid, gel, or solid)

FunctionBinds and/or supports other tissue

Slide66

Summary

True (Proper) Connective Tissue

Loose CT (

aereolar

, adipose, reticular)

Dense CT (regular, irregular)

Supportive Connective Tissue

Cartilage

BoneLiquid Connective TissueBloodLymph

Types of Connective Tissue:

Slide67

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