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 Diabetes and Dyslipidemia  Diabetes and Dyslipidemia

Diabetes and Dyslipidemia - PowerPoint Presentation

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Uploaded On 2020-04-03

Diabetes and Dyslipidemia - PPT Presentation

2013 ACCAHA Guideline on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults IMPROVEIT 2012 Update of the Canadian Cardiovascular Society Guidelines for the Diagnosis and Treatment of Dyslipidemia ID: 774852

odyssey ldl lowering references odyssey ldl lowering references cont cardiovascular trials improve long term risk diabetes abbreviations dyslipidemia patient

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Presentation Transcript

Slide1

Diabetes and Dyslipidemia

Slide2

2013 ACC/AHA Guideline on theTreatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults

Slide3

IMPROVE-IT

Slide4

2012 Update of the Canadian Cardiovascular Society Guidelines for the Diagnosis and Treatment of Dyslipidemia

Slide5

Achieved LDL < 50 mg/dL Has a Greater Relative Risk Reduction Than Higher Levels

Slide6

ACCORD Primary Outcome Event Rate

Slide7

IMPROVE-IT Diabetes

Slide8

ODYSSEY LONG TERM LDL lowering

Slide9

ODYSSEY LONG TERM Safety

Slide10

Coronary Atheroma Regression as a Function of LDL Lowering

Slide11

Management of a Patient With SAMSStep V: Rechallenge the patient repetitively

Slide12

ODYSSEY AlternativeStudy Design

Slide13

ODYSSEY Alternative

Slide14

ONGOING LIPID Lowering Trials

Slide15

Post-hoc Adjudicated Cardiovascular TEAEs† Pooled From Phase 3 Placebo-controlled Trials

Slide16

Cholesteryl Ester Transfer Protein InhibitorsA Note of Caution

Slide17

Abbreviations

Slide18

Abbreviations (cont)

Slide19

References

Slide20

References (cont)

Slide21

References (cont)