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Dual Antiretroviral Therapy Dual Antiretroviral Therapy

Dual Antiretroviral Therapy - PowerPoint Presentation

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Uploaded On 2018-12-04

Dual Antiretroviral Therapy - PPT Presentation

This program will include a discussion of offlabel treatment and investigational agents not approved by the FDA for use in the United States and data that were presented in abstract form These data should be considered preliminary until published in a peerreviewed journal ID: 734694

dual therapy regimens treatment therapy dual treatment regimens triple dtg rpv based 3tc sword initial drug integrase inhibitor data

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Presentation Transcript

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Dual Antiretroviral TherapySlide2
Slide3

This program will include a discussion of off-label treatment and investigational agents not approved by the FDA for use in the United States and data that were presented in abstract form. These data should be considered preliminary until published in a peer-reviewed journal.Slide4

Current Paradigm: Triple Therapy Is Very EffectiveSlide5

Good Adherence With Single-Tablet Triple-Therapy RegimensSlide6

Recent Advances: Agents and RegimensSlide7

From Triple Therapy to Dual TherapySlide8

From Triple Therapy to Dual Therapy

Potential AdvantagesSlide9

From Triple Therapy to Dual Therapy

Potential Advantages (cont)Slide10

Dual Therapy: Some Early Attempts That Fell Short

Maintenance TreatmentSlide11

Dual Therapy: Some Early Attempts That Fell Short

Initial TreatmentSlide12

Dual Therapy Success With PI/b + 3TC Regimens

Initial TreatmentSlide13

Dual Therapy Success With PI/b + 3TC Regimens

Initial TreatmentSlide14

From PI/b-Based to Integrase Inhibitor-Based RegimensSlide15

Integrase Inhibitor-Based 2-Drug Regimens

DTG + 3TC in Treatment-Naive PatientsSlide16

Integrase-Based 2-Drug Regimens

DTG + 3TC in Treatment-Experienced PatientsSlide17

Long-Acting Injectables: CAB/RPV StudiesSlide18

DTG/RPV: First 2-Drug STR

SWORD 1 and SWORD 2Slide19

SWORD: Tolerability and SafetySlide20

DTG/RPV: IndicationSlide21

Patient Selection for DTG/RPVSlide22

Concluding RemarksSlide23