mJ cm 2 was range of UV irradiation Supplementary data Figure S2 Total phenolic and flavonoid contents of DW extract of Nypa fruticans NFD and 100 EtOH extract of Nypa ID: 1037925
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1. Figure S1. Experimental schedule of UV irradiation intensity and time. 75 to 300 mJ/cm2 was range of UV irradiation.
2. Supplementary data Figure S2. Total phenolic and flavonoid contents of DW extract of Nypa fruticans (NFD) and 100% EtOH extract of Nypa fruticans (NFE)
3. Supplementary data Figure S3. DPPH-radical scavenging activity of NFD and NFE. Ascorbic acid were used as positive control. The results are shown as means SD performed in triplicates (** P < 0.05).
4. Supplementary data Figure S4. Effects of ABTS-radical inhibition activity by NFD and NFE. Ascorbic acid were used as positive control. The results are shown as means SD performed in triplicates (** P < 0.05).
5. Supplementary data Figure S5. Reducing antioxidant capacity of NFD and NFE. It was calculated by ascorbic acid equivalent value (µM).
6. Supplementary data Figure S6. Elastase inhibition activity of NFD and NFE. EGCG was used as positive control. The results are shown as means SD performed in triplicates (** P < 0.05).
7. Supplementary data Figure S7. Cell viability of NFD and NFE using MTT assay.
8. Figure S8. Effect of NF50E on mRNA expression of Col1a1, MMP-8 and -13 were done by RT-PCR analysis.
9. Figure S9. Phosphorylation of ERK by NF50E was performed by western blot analysis.