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1 7 7 in this but the Lutt et in this and
7 7 in this but the Lutt et in this and one but not the eight adult plug held on a 0 4960 17 5031 38 5676 87 4133 227 5986 but not but the to that of such as 74
2 , 83, and 70 1.82 0.21 162 861 53 478 an
, 83, and 70 1.82 0.21 162 861 53 478 and 5094 and a and n 1 and on a and 100 d 100 d not the 4 and 41 A AAAA 50 100 150 227 d but the 3 and a 0.5, 1, 2, 17, 38,
3 and 87 d 2 4 6 8 10 12 14 0 2 4 6 8 10
and 87 d 2 4 6 8 10 12 14 0 2 4 6 8 10 12 14 16 2 20 2 4 6 8 10 12 14 16 0 2 4 6 8 10 12 14 16 I3 to 38 d listed in in this 6 2 4 6 8 10 12 14 I I 0 2 4 6 10 1
4 2 14 16 2 4 6 8 10 12 14 16 0 2 4 6 8 10
2 14 16 2 4 6 8 10 12 14 16 0 2 4 6 8 10 12 14 16 3 and 20 d 17 d and a be a 2164 Gordon et al. l Stimulation of Axotomized Nerves Figure 9. Comparisons of cross
5 sec- tions of normal (A) and axotomized
sec- tions of normal (A) and axotomized CP nerves (B, C). CP nerves were sectioned and ligated bilaterally at a distance of 25 mm from the cuff electrode. The le
6 ft CP nerve (c) was chronically stimulat
ft CP nerve (c) was chronically stimulat- ed in trains at 99 pulses at 100 Hz every 5 set for 8 hr/d for 227 d, and the right CP was not stimulated, except during
7 recording sessions (B, see Fig. 5). The
recording sessions (B, see Fig. 5). The cross sections were obtained 15 mm from the site of ligation. Note the great- er proportion of large fibers in the nor- m
8 al nerve (A) relative to axotomized nerv
al nerve (A) relative to axotomized nerves and the larger proportion of large fibers in the unstimulated (B) as com- pared to the stimulated (C) axotomized nerves
9 . Magnification, 984 x . in cytoskeletal
. Magnification, 984 x . in cytoskeletal protein synthesis and transport are more likely dium, and hydrogen, which may be involved in alterations in to account fo
10 r the first rapid phase of decline in fi
r the first rapid phase of decline in fiber caliber cytoskeletal proteins. In addition, substances may be taken up after axotomy. Polymerization of neurofilaments
11 is sensitive to at the injury site and
is sensitive to at the injury site and contribute to local changes during the first several local factors that may operate to reduce their number. phase of decli
12 ne as well as to later changes in gene e
ne as well as to later changes in gene expression These include changes in local concentrations of calcium, so- after retrograde transport to the soma. Our result
13 s suggest that 221 d 4 6 8 10 12 14 16
s suggest that 221 d 4 6 8 10 12 14 16 0 2 4 6 8 10 12 14 105 and 227 d 4 and trophic control be an G, Vrbova G, depend on on L7 Taylor JF, (1989) Target in s