SCENARIO Here is a 35years old female patient admitted in medicine female ward diagnosed as dimorphic anemia was hospitalized for 6 days CHIEF COMPLAINTS co breathlessness since 15 days co giddiness since 15 days ID: 918897
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Slide1
Major case presentationDimorphic anemia
Slide2SCENARIO:
Here is a 35years old female patient admitted in medicine female
ward diagnosed as dimorphic anemia was hospitalized for 6 days.
CHIEF COMPLAINTS:
c/o breathlessness since 15 days
c/o giddiness since 15 days
HISTORY OF PRESENT ILLNESS: Patient was apparently alright
15 days back then she developed breathlessness, insidious in onset
a
nd progressive. Patient also complains of giddiness even at rest
g
radually progressive.
PAST MEDICAL HISTORY:
Patient is a k/c/o anemia blood transfusion was done when she delivered
second child
Slide3LABORATORY INVESTIGATION:
Peripheral smear report:
Dimorphic anemia with leucopoenia with mild thrombocytopenia
Test
Patient value
Normal value
WBC
4500 cumm
4000-11000 cumm
RBC
1.12
million/
μ
l
4.0-5.5
million/
μ
l
Hb
4.5 g/dl
11-14g/dl
PCV
12.3 %
35-46%
MCV
109.8 fl
80-100fl
MCHC
36.6 g/dl
32-36 g/dl
MCH
40.2 g/dl
32-36 g/dl
ESR
70 mm/hr
<20 mm/hr
MPV
13.0
fl
7.4-11.4
fl
PDW
15.7 fl
10-14 fl
Platelet count
1.50
1-3
lakhcell
/cumm
Slide4General physical examination:
Pallor +
SOAP NOTE:Subjective:Here is a 35 years old female presenting complaints of breathlessnessand giddiness since 15 days.Objective:RBC is decreased that indicates anemia.Hb is drastically decreased which indicates severe anemiaESR is increased due to infectionPCV is decreased that indicates over hydration or due to anemia or blood loss.
Slide5MCV & MCH values are increased which indicates
macrocytic
&
hyperchromia.RDW (RBC distribution width)the normal values are found in anemia.MPV (mean platelet vol ) is increased it indicates there is destruction of platelets. (Alloimmune thrombocytopenia - eg, neonatal, post-transfusion)PDW (platelet distribution width) is increased it indicates high PDW means that platelet size varies greatly, a sign of active platelet release.Peripheral smear shows that dimorphic anemia with
leucopeonia
with mild thrombocytopenia.
Diagnosis:by
observing the above subjective and objective data the patient is diagnosed with dimorphic anemia.
Slide6ASSESSMENT:
Problem list:
1.Breathlessness
2.Giddiness3.Dimorphic anemia-Breathlessness:It is due to anemia the oxygen carrying capacity is decreased.-Giddiness:It is due to anemiaDimorphic anemia : is a dual population of RBCs in the peripheral blood smear with both microcytic
hypochromic
and
normocytic
macrocytic
red blood cells which is a typical finding of iron
deficiency vitamin B12/folic acid deficiency anemia.
Slide7PLAN OF CARE:
Goals of therapy:
To alleviate signs and symptoms
Correcting the underlying etiology Prevent reoccurence of anemia.
Slide8S.no
Brand name
Generic name
Dose & freuencyDay1234561.IVF dextrose500mlYY
Y
Y
Y
Y
2.
O2
inhalation
Y
Y
3.
Inj.Bactocef
iv
Cefuroxime
1gm
1-0-1
Y
Y
Y
Y
Y
Y
4.
Inj.Pantox
iv
Pantoprazole
40mg
1-0-0
Y
Y
Y
Y
Y
Y
5.
Inj.P-cet
iv
Ondansetron
1amp
1-1-1
Y
Y
Y
Y
Y
Y
6.
Syp.Hemowin
Oral iron supplement
2tsp
0-0-1
Y
Y
Y
Y
Y
Y
7.
Inj.Vitcofol
im
Folic acid
2cc
0-1-0
Y
Y
Y
Y
8.
Cap.Fesovit
FA+
nico+B6+B12 + Feso4
0-1-0
Y
Slide9Drug-drug interactions:
Cefuroxime +
pantoprazole
- decreases the absorption of cefuroxime Monitor CBC for the normal levels RBC,Hb Patient counselling:Patient is advised to take iron rich diet such as green leafy vegetables, fruits, egg, liver, kidney etc,Discharge drugs:
1.syp.Hemowin 2tsp -0-0-1 x 10 days
2. cap.
Fesovit
0-1-0 x 30 days
3. Inj.
Vitcofol
2cc
im
0-1-0 alternate days for 1 wk.
Slide10THANK YOU