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Neonatal GI  Problems 1: Neonatal GI  Problems 1:

Neonatal GI Problems 1: - PowerPoint Presentation

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Neonatal GI Problems 1: - PPT Presentation

The Surgical Abdomen Obstruction CHO NICU Lecture PJ AD DD Revised 062911 Causes of GI Obstruction Upper Tract Esophageal atresia tracheoesophageal atresia Gastric causes ID: 777216

atresia meconium obstruction colon meconium atresia colon obstruction bowel abdominal esophageal perforation duodenal small stenosis distention bilious normal fistula

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Slide1

Neonatal GI Problems 1:The “Surgical Abdomen”Obstruction

CHO NICU Lecture

PJ, AD, DD

Revised 06/29/11

Slide2

Causes of GI ObstructionUpper Tract

Esophageal atresia +/-

tracheoesophageal

atresia

Gastric causes:

antral

web, bezoar

Pyloric stenosis

Duodenal

atresia/stenosis,

annular pancreas

duodenal web

Malrotation

volvulus

Slide3

Causes of GI ObstructionMid-Gut

Jejunal

atresia

Ileal

atresia

Meconium ileus (associated with cystic fibrosis)

Small bowel perforation

NEC

Adhesions, strictures

Intussusception

Appendicitis

Abdominal wall defects

Omphalocele

Gastroschisis

Slide4

Causes of GI ObstructionDistal Gut

Colonic atresia/stenosis

Hirschsprung’s

disease

Meconium plug syndrome (associated with

Hirschsprungs

)

Small left colon syndrome (IDM)

Incarcerated inguinal hernia

Imperforate anus

Slide5

Non-Surgical Causes of IleusSepsisUTI

Electrolyte abnormalities:

Hypokalemia

Hypermagnesemia

Drugs:

morphine

Slide6

Intestinal Obstruction

Symptoms and findings might include

:

Abdominal distention

Emesis

(bilious

)

Tenderness

Visible

loops of bowel, abdominal wall erythema

Associated problems:

Respiratory compromise, apnea

Hypovolemia

, hypotension

Sepsis (NEC, perforation)

Electrolyte imbalance

Neutropenia (sepsis

)

Thrombocytopenia

(sepsis, perforation, bowel necrosis

)

Check for incarcerated inguinal hernia, imperforate anus

Slide7

Treatment of Intestinal ObstructionNG/OG to low intermittent suction

Correct

hypovolemia

and hypotension

Third spacing into the lumen of the distended bowel

IV Fluids

D5/D10

with 1/2

NS

at 120-150 mL/kg/day

Correct electrolyte abnormalities and acidosis

Blood

culture and Antibiotics

Ampicillin

,

Gentamicin

,

Flagyl

(sometimes)

Respiratory

support for abdominal distension or apnea

Slide8

TEF/EA

Slide9

Slide10

Slide11

Tracheo-esophageal fistula and esophageal atresia

Slide12

Esophageal Atresia & Tracheo-esophageal

Fistula Symptoms

Respiratory distress from aspiration

Poor handling of secretions: drooling, frequent suctioning, choking or other symptoms with feeding

Inability to pass OG/NG to stomach

Abdominal distention may occur with swallowing of air through TEF or due to associated anal atresia

Slide13

Esophageal Atresia & Tracheoesophageal

Fistula Associated Problems

Prematurity

RDS, pulmonary aspiration

VACTERL (vertebral anomalies, anal atresia, cardiac anomalies, TEF, renal, limb)

Abdominal distention due to air passed through TEF can cause gastric perforation

Slide14

Esophageal Atresia & Tracheoesophageal

Fistula:

Management

CXR with tube to the pharyngeal pouch

LIS to the pharyngeal tube

Blood culture, ampicillin and gentamicin

Manage respiratory

problems

Examine

for anomalies: VACTERL

Slide15

Bilious Vomiting40% of babies with bilious vomiting require surgical interventionBilious vomiting in the neonate is due to mechanical obstruction until proven

otherwise

Slide16

Malrotation1/5000 live births80% occur during 1st

month of

life

most

during the 1

st

week of life

Higher incidence in

males (2:1)

Normal exam early during course

Sx

of

obstruction:

Bilious

vomiting

Sx

of

bowel ischemia:

Bloody

stool, abdominal distension, tenderness, shock

Slide17

Normal fixation of

mesentary

Slide18

Malrotation with ObstructionFailure of fixation and rotation of midgut, small bowel, right colon, and transverse colon

Duodenal obstruction from Ladd’s bands

Slide19

Malrotation with VolvulusSmall bowel twists around superior mesenteric artery, causing ischemia

Slide20

Malrotation/VolvulusAbdominal XRay

Normal film -20%

Dilated duodenal bulb and paucity of distal bowel gas

Double bubble sign

Distal gas filled bowel loops; gas filled volvulus (obstructed mesenteric veins prevent absorption of gas

Slide21

Slide22

Slide23

Slide24

Duodenal AtresiaPolyhydramniosPartial obstructions: duodenal web, duodenal

stenosis

, annular pancreas

40% of cases associated with

trisomy

21

Most common gut

atresia

in

neonates

“Double bubble”

Slide25

Slide26

Slide27

Hirschsprung’s DiseaseFailure to pass meconium in 1

st

24

hrs

Absence of ganglion cells in mesenteric plexus

Most commonly

rectosigmoid

junction

10% of cases involve entire colon

10% of cases associated with Trisomy 21

Slide28

Slide29

Slide30

Hirschsprung’s DiseaseContrast enemaSuction biopsyOpen biopsy

Rectal irrigation

Colostomy

vs

primary pull-through

Slide31

In Utero PerforationCaused by obstruction:

Meconium

Ileus

Hirschprungs

Volvulus

Early perforation leads to Ca

++

deposits

Later perforation may cause

ascites

, no Ca

++

Adhesions lead to obstruction

Slide32

Slide33

Meconium IleusUsually a manifestation of cystic fibrosis

20% of infants with CF present with

mec

ileus

Obstruction of proximal ileum by thick, sticky round

meconium

pellets

Absence of air fluid

levels

soap bubbles”

Complications

:

perforation

, peritonitis,

pseudocyst

,

ileal

atresia

/

stenosis

Slide34

Meconium IleusContrast enema:Small colon

Filled with pellet-like

meconium

when contrast extends to IC valve

Contrast can wash out the obstructing plugs and

meconium

plugs

The diagnosis of CF should

be

ruled-out

Slide35

Slide36

Slide37

Slide38

Meconium Plug SyndromeDiagnosis of exclusionProbably same as "small left colon" syndromeTransient

disorder due to functional immaturity of colon

Common in IDM,

premies

, PIH, Mg Rx

Infants with CF may present with

mec

plugs, although

mec

ileus

most common

10-30% may have

Hirschsprungs

also

Slide39

Meconium Plug SyndromePresent within the first 24 to 36 hours of age:Abdominal distention

Vomiting (bilious)

Failure to pass

meconium

Plain films show distal intestinal obstruction

Contrast enema usually shows:

distention of the right and transverse colon

transition near the

splenic

flexure to a narrow descending colon and

rectosigmoid

region

Meconium

within the colon

Main differential diagnosis is

Hirschsprung's

disease:

In

Hirschsprung's

disease,

aganglionic

colon is usually normal caliber

In

Meconium

Plug Syndrome, colon is usually small

Slide40

Slide41