AT KENYATTA NATIONAL HOSPITAL Dr Rugendo Birichi A Dr Karimi Peter N Dr Amugune Beatrice K Medication related problems occur when outcome of medicine use is not optimal ID: 578010
Download Presentation The PPT/PDF document "EFFECTS OF INTRODUTION OF INDIVIDUALISED..." is the property of its rightful owner. Permission is granted to download and print the materials on this web site for personal, non-commercial use only, and to display it on your personal computer provided you do not modify the materials and that you retain all copyright notices contained in the materials. By downloading content from our website, you accept the terms of this agreement.
Slide1
EFFECTS OF INTRODUTION OF INDIVIDUALISED DISPENSING ON MEDICATION RELATED PROBLEMS AT KENYATTA NATIONAL HOSPITAL.
Dr Rugendo Birichi A
Dr
Karimi Peter
N
Dr
Amugune Beatrice KSlide2
Medication related problems occur when outcome of medicine use is not optimal.Systems to prescribe, distribute and administer medicines have influence on medication safety by minimising medication related problems(MRP’s).
BACKGROUNDSlide3
BACKGROUNDKenyatta National Hospital(KNH) has used a mixed system of dispensing to inpatients.
associated with medication related problems(MRP)
Shifted to individual order system in 2013
Effect of change on MRP’S not evaluatedSlide4
To compare the types of medication related problems before and after introduction of
individualised
dispensing.
To compare the frequency of medication related problems before and after.
Specific objectivesSlide5
A cross sectional study(pre-post) design.
systematic random sample of 236 before and 207patient files for the after study arm.
Study site- KNH medical wards
ethical approval was sought and granted by the KNH/UON ethics committee.
MethodologySlide6
Methodology......
Data was abstracted from patient’s files.
The treatment chart , the medical notes, nursing notes and laboratory reports were assessed.
Mediscape drug interaction checker was used.
Data analysis was performed using Statistical Package for social scientist (SPSS) version20 Slide7
RESULTSSlide8
Results:Socio-Demographic traits of patients
characteristic
category
Frequency/percentage
Before
After
gender
Male
115(48.7 %)
98( 47.3%)
Female
121( 51.3 %)
109 (52.7 %)
Age
Mean
31.4 years
36.9 years
Range
13 to 84 years
13 to
102 yearsSlide9
Results: TYPE AND FREQUENCY OF MRP
trait
categories
Frequency/percentage
P Value
Before
After
duration
missing
195(83 %)
149(72% )
0.000001
ADR
Presence
26( 11 %)
18( 8.7 %)
0.0173
Non -adherence
191(80.9%
189(91.3%
0.00182
Dose
Low
3(1.3%)
2(1%)
0.4234
High
0
2(1%)
Adjustment
25(10.6%)
26(12.6%)
Drug-drug interaction
191(80.9
%
165(69.9
%
0.8248Slide10Slide11
The mean drug availability was 87. 5 % (before) and 86.92 % (after)
MEDICINE AVAILABILITYSlide12
DRUG-DRUG INTERACTIONSlide13
BIVARIATE ANALYSISPatients with 8-11 drugs per prescription had the highest prevalence of MRP’s
while
the 1-3 category had the lowest [p<0.001].Slide14
conclusionStudy demonstrated a high prevalence of MRP before and after change of dispensing system
There was a statistically significant difference in prevalence of non-adherence, adverse drug reactions and indicated treatment duration in the two study groups. Slide15
Research and programs department KNHHealth information department KNH
School of Pharmacy, UON.
ACKNOWLEDGEMENTSlide16