Dose response curves after single dose SD application under clamp conditions with black and without green WBI Symbols observed local control rates curves calculated local tumour control ID: 796841
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Slide1
p=0.83
Supplementary Figure 1: Effect of whole body irradiation (WBI) on local tumour control for SAT
.
Dose response curves after single dose (SD) application under clamp conditions with (black) and without (green)
WBI
.
Symbols: observed local control rates; curves:
calculated local tumour control
probabilities
(TCP);
error bars represent
95
%
confidence intervals
(
CI)
of the tumour control
dose 50% (TCD
50
)
value
.
Slide2CAL-33
UT-SCC-15
XF354
UT-SCC-14
UT-SCC-8
SAT
UT-SCC-45
UT-SCC-5
SAS
FaDu
EGFR
CEP-7
EGFR
CEP-7
EGFR
CEP-7
EGFR
CEP-7
EGFR
CEP-7
XF354 UT-SCC-15
UT-SCC-8
SAT UT-SCC-45 UT-SCC-5 SAS FaDu
UT-SCC-14 CAL-33
Ratio
EGFR
/ CEP-7
normal
CEP-7
CEP-7
CEP-7
CEP-7
CEP-7
EGFR
EGFR
EGFR
EGFR
EGFR
Supplementary Figure
2
:
EGFR
amplification status (
EGFR
/CEP-7
ratio)
for 10 tumour
models was
identified using
FISH analysis.
FISH values from UT-SCC-15, SAS, FaDu, UT-SCC-14 and CAL-33 were taken from Gurtner et al. [
14]
amplified