ME M yalgic Encephalomyelitis in Norway Marianne Bjærum Christine Normann What is ME Temporary unknown cause Officially called Chronic Fatigue Syndrome F irst classified into the ID: 492298
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Slide1
New development in ME – Myalgic Encephalomyelitisin Norway
Marianne
Bjærum
Christine
NormannSlide2
What is ME?Temporary unknown causeOfficially called “Chronic Fatigue Syndrome”F
irst classified into the
International Classification of Diseases
in 1969
In Norway alone it is estimated that 15.000 people have ME – predominantly women
No test exist, therefore excluding other diseases is important for diagnosisSlide3
SymptomsImpaired memory and cognitive complaintsSore throat
Tender cervical or
axillary
lymph nodes
Muscle pain
Multi-joint pain
New headaches
Un-refreshing sleep
Post-
exertional
malaise lasting more than 24 hoursSlide4
New researchA study published in 2009 in “Science” reported an association between ME and a retrovirusIn September 2011, the authors published a "Partial Retraction" of their 2009 findingsSlide5
New researchOctober 2011, A Study at Haukeland University hospital, Bergen,
Norway
Cancer treatment improved patients CFS conditions
Randomised, double-blind study, 30 patients
2 out of 3 patients with improved conditionSlide6
RituximabA chimeric monoclonal antibody that attacks the B-lymphocytes
U
sed
in the treatment of many lymphomas,
leukemias
and some autoimmune
disorders
D
estroys
both normal and malignant
B-
ly
that
have
CD20 on
their
surfaces
T
herefore
used to treat diseases which are characterized by having too many
B-
ly
,
overactive B-
ly
or dysfunctional
B-
lySlide7
TheoriesAutoimmune diseaseA big subgroup of these
patients
have a autoimmune disease maintaining itself by a autoantibody
.
T
he B-lymphocytes
act as a reservoir for a virus with a big impact on this disease. Slide8
Newly releasedResearch article: Benefit from B-Lymphocyte Depletion Using the Anti-CD20 Antibody Rituximab in Chronic Fatigue Syndrome. A Double-Blind and Placebo-Controlled
Study
New
book released in October in Norway – historically, politically, national and international, and how to live with MESlide9
Resourceshttp://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0026358http://www.me-foreningen.no/
http://en.wikipedia.org/wiki/Chronic_fatigue_syndrome
http://www.cfids.org/community/pcpep/curriculum.asp