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S2418 Inhibitor of Nuclear Factor Kappa-B Kinase Subunit S2418 Inhibitor of Nuclear Factor Kappa-B Kinase Subunit

S2418 Inhibitor of Nuclear Factor Kappa-B Kinase Subunit - PowerPoint Presentation

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Uploaded On 2018-03-17

S2418 Inhibitor of Nuclear Factor Kappa-B Kinase Subunit - PPT Presentation

Alpha Kinections Map O15111 IKK a CHUK O15111 S180 S176 T23 Y187 Akt1 PKB a P31749 Akt2 PKB b P31751 Akt3 PKB g Q9Y243 NIKMAP3K14 Q99558 FOXO3FKHRL1 O43524 S644 ID: 654939

o15111 pkb pkb o15111

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Presentation Transcript

Slide1

S2418

Inhibitor of Nuclear Factor Kappa-B Kinase Subunit

Alpha

Kinections

Map O15111

IKK

a

/CHUK

O15111

+S180

+S176

+T23

+Y187

Akt1/

PKB

a

P31749

Akt2/

PKB

b

P31751

Akt3/

PKB

g

Q9Y243

NIK/MAP3K14

Q99558

FOXO3/FKHRL1

O43524

-S644

CREBBP

Q92793

NFkappaB

P19838

IRS1

P35568

-S312

NF

k

B-p100

Q00653

S872

S123

REL

Q04864

S557

NCOR2/SMRT

Q9Y618

I

k

B

a

P25963

-S36

-S32

-S932

-S927

-S923

S2335

S2332

NCOR1

O75376

S90

PIAS1

O75925

ER

a

/ESR1

P03372

+S118

Cyclin

D1/CCND1

P24385

T286

S115

S108

S99

NF

k

B-p65/

RelA

Q04206

S536

Histone H3.2

P84228

+S11

CTNNB1

P35222

+S45

T41

S37

-S33

+S1386

+S1382

NCOA3/SRC-3

Q9Y6Q9

+S857