during OneLung Ventilation Author n End Points Outcome Cohen E et al J Cardiothorac Vasc Anesth 1996 1057882 ref 30 n18 prospective Hypothesis pts with low PaO 2 lt ID: 164327
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The Effects of PEEP on Oxygenation during One-Lung Ventilation
Authorn End PointsOutcomeCohen E, et alJ Cardiothorac Vasc Anesth1996; 10:578-82[ref 30]n=18(prospective)Hypothesis pts with low PaO2 (<80 mmHg) during OLV may benefit from PEEP 10 cmH2On=11 pts with PaO2 <80 mmHg FiO2 0.5% OLV PaO2 + PEEP (10) 65 ± 7 87 ± 32Ren Y, et alAnaesth Intensive Care 2008; 36:544-48 [ref 35]n=30 OLV(prospective)Best time Level of PEEP Group A – 0, 5, 10 cmH2O B – 5 cm H2O C – 10, 5, 0 cmH2OPaO2 lower w/o PEEPPaO2 better with 5 or 10 PEEP10 cm H2O PEEP ↑Ppeak and PplatHoftman N, et alAnn Card Anaesth2011; 14:183-187[ref 36]n=41 OLV(prospective)Efficacy of PEEP Preop predictors of response to PEEPOLV PEEP, 5 (15 min) PEEP, 10 (15 min)PEEP improved arterial oxygenation by ≥20% only 29% (n=12)Failure to improve oxygenation 71%Only VT 6.6 ml•kg among responders with PEEP