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Division of Alcoholism and Substance Abuse Drug Overdose Prevention Program Training Module Dr Seth Eisenberg MD Rosie Gianforte LCSW Overview of the HeroinOpiate Problem Illinois Public Act 0990480 HB0001 ID: 742215

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Slide1

Illinois Department of Human ServicesDivision of Alcoholism and Substance Abuse

Drug Overdose Prevention Program

Training

Module

Dr. Seth Eisenberg, MD

Rosie Gianforte, LCSWSlide2

Overview of the Heroin/Opiate Problem

Illinois Public Act 099-0480 (HB0001)IDHS/DASA Drug Overdose Prevention Program (DOPP) and how to enroll Identifying

Opioid OverdosesHow to Respond to an OverdoseUse of NaloxoneAfter Naloxone – Outreach Efforts/Treatment Referrals

TOPICSSlide3

OBJECTIVES

Explain the risk factors for opioid abuse and overdose and discuss strategies for preventing overdoseGain an understanding of the opiate overdose

problem & how opioids workIdentify people

who meet the criteria for the provision of naloxone, and explain how to respond to opioid overdoseCompare the different types of Naloxone:Intra-nasal Intra-muscular Slide4

OBJECTIVES (cont.)Explain how a person will respond to naloxone rescue

therapy and discuss managing adverse events following the use of naloxone rescue therapyDiscuss indications, contraindications, safety, any drug interactions, and adverse effects of naloxone rescue therapy

Explore Medication Assisted Treatment MAT Options(PA 99-0553) Effective January 1, 2017, all substance use treatment programs licensed by IDHS/DASA must provide educational information to clients identified as having or seeking treatment for opioid use disorder, including the use of a medication for the use of opioid use disorder, recognition of and response to opioid overdose, and the use and administration of

naloxoneRecommend support programs and resources for clients and care-givers for follow-up care for opioid use disorder.Slide5

Overview of the problemWhy focus on the heroin/opioid epidemic?Slide6

Opioids Opioids are a class of drugs in both legal (prescription medications such as oxycodone, hydrocodone, morphine, fentanyl) and illegal(heroin) forms.

Opioids are natural or synthetic substances that act on the brains opiate receptors.Opioids dull pain and relieve anxiety. People may misuse opioids because they are in pain (physical and emotional) and opioids produce a feeling of euphoria. Slide7

2004

2008

2006

2010

2014

2012Slide8

A NATIONAL EPIDEMIC

According to the Centers for Disease Control:

Between 2000 – 2013,

Deaths from prescription opioid overdose death more than tripled. In 2014, 52 people died every day

as a result of an overdose from a prescription

painkiller.

In

2014, almost 2 million

Americans

abused or were dependent on prescription

opioids

Every day, over 1,000 people are treated in emergency departments for misusing prescription opioids.Slide9

According to the Centers for Disease Control:

Since 2010, Heroin-related overdose deaths have more than quadrupled

.More than nine in 10 people who used heroin in also used at least one other drug.Among new heroin users, approximately three out of four report having abused prescription opioids prior to using heroin.Slide10

FentanylFentanyl is a synthetic opioid pain reliever that is much more powerful than any other opioids. It is prescribed for severe pain, such as advanced cancer pain. It has been illegally made and distributed through illegal drug markets, and is often mixed with heroin and other drugs, sometimes without the buyer’s knowledge.

Fentanyl overdoses are more lethal than heroin or prescription opioids alone.Overdose deaths involving synthetic opioids, which includes fentanyl, increased by 80% from 2013 to 2014.Slide11

Opioid and Heroin Death StatisticsSlide12

IN ILLINOIS – the Opiate crisis 2013 - 2015

Illinois was one of 14 states with statistically significant increases in overall drug overdose deaths between 2013 and 2014.Opioid drug overdoses killed 45% more people than homicides

The Chicago Metropolitan area ranks first nationwide in emergency department mentions for heroin use. Cook County ranks first in the nation for percentage of arrestees testing positive for opiates.

Source: Illinois Department of Public HealthSlide13

IN ILLINOIS drug poisoning deaths 2013-2015

Source: CDC/statistics 2014

3,614

were due to opioids2,113 were due to heroin1,344 were due to prescription opioidsSlide14

Who is at risk of an overdose?

Anyone who may use opioids for chronic cancer pain or non-cancer pain, as well as people who use heroin,

may be at risk for opioid overdoseSome situations that may increase a person’s risk include:

Switching between opioids Mixing opioids with depressants, such as alcohol or benzodiazepines; such as oxycodone and xanax and alcohol.People with chronic medical conditions (Substance Use Disorders, HIV

, cardiovascular or respiratory disease, mental

illnesses) or homeless conditions;

Recently

released from incarceration and in-patient

tx

programs.

Recently completing a mandatory opioid detoxification or having abstained from use for a period of time; the person’s tolerance has decreased but they have a high risk of relapse

Discharge from emergency medical care after opioid intoxication Slide15

How to Reduce the risk overdose

Talk to people and caregivers about ways to avoid an accidental overdose, especially at discharge:Do not

adjust prescribed dosage, skip doses, or take any extra dosesDo not mix with other dugs and/or alcohol (i.e. anti-anxiety drugs like benzodiazepines, antidepressants, or cocaine)

Abstain from use of opioids unless prescribed, and attempt abstinence from heroin. Slide16

Signs of Overmedication and Recognizing an overdoseSlide17

Overdose

Overdose is an acute condition that usually occurs over 1-3 hours

May be caused by: Excess intake of opioids

Combination of opioid and a Central Nervous System depressantOpioid use in someone with a compromised respiratory system or metabolic conditionSlide18

OverdoseSlide19

recognizing

Mechanisms of overdoseSlide20

How to recognize an overdoseThe difference between being high and overdosing is if the patient is responsive or not.

Other signs to look for include:In an opiate overdose, the person’s breathing will be slow and shallow, their coloring may be pale or blue, and they may be snoring or gurglingIn a stimulant overdose, the person may have chest pain, difficulty breathing, dizziness, vomiting, foaming at the mouth, lots of sweat or NO sweat, a racing pulse, and/or seizures

Checking for a response (downer/opioid overdose)Make noise, call the person’s name

Shake the person, rub their sternum or forehead with knucklesCheck that their airway is clear by tilting their head back and lifting their chinCheck for syringe caps, undissolved pills, fentanyl patches in their cheek, toothpicks, gum, etc. Slide21

Legislative RESPONSESlide22
Slide23

Illinois Public Act 099-0480 (HB1)

Illinois Public Act 099-0480 (HB0001) passed and became effective September 9, 2015.Enables non-medical persons to administer Naloxone to persons experiencing an opioid overdose

Requires emergency responders such as EMS, firefighters, law enforcement, and pharmacists to be trained in administering Naloxone through its various forms of administration

Updates previous laws and Allows Department of Human Services- DASA to further implement the Drug Overdose Prevention Program (DOPP) to encourage, establish and authorize programs to become enrolled to distribute naloxone statewide.Slide24

Drug Overdose Prevention Program (DOPP)Potential enrollees

include: DASA Treatment Programs and Recovery HomesLicensed prescribing

practitionersFor profit community-based organizations & not-for- profit community-based

organizationsHospitals, and Local Health Departments, Health

care providers, including FQHCs and Health Care for the Homeless clinics, urgent care facilities, faith-based organizations.

Agencies

engaged with incarcerated individuals, such as jails, prisons, probation and parole, problem-solving courts, and

Police

and

Sheriff

departments Slide25

Ways of “Providing” NaloxoneSlide26

What is naloxone and how does it work?Naloxone is an opioid receptor antagonist that works by reversing both the clinical and toxic effects of the overdose. It works by blocking the opioid’s action on the brain and restoring breathing.

The only purpose is to reverse overdose; there is no abuse potential and this medication cannot produce a “high”Slide27

ACTION PLAN STEPSSlide28

Action PlanStay Calm

Give Sternal Rub (Call out persons name and shake shoulders)Call

911 for Emergency Rescue Responder Services Perform Rescue Breathing

and Chest Compression TechniquesAdminister Naloxone either through muscular injection or nasal spray.

Continue rescue breathing for 3-5 mins, if person is still not responding administer second dose of Naloxone

Goal is to restore adequate breathing, but not necessarily complete arousal

Stay with person until Emergency Responders arrive. If person is still unconscious but breathing on his/her own, put him or her in recovery

position

.Slide29

TIPS for Calling 9-1-1 & Naloxone

Whichever you can do the quickest – DO FIRST! Tell the dispatcher the person has stopped breathing The dispatcher may give instructions on rescue breathing or chest compressionsHave the address and location ready

The dispatcher may connect you with the paramedics who will ask you the same questions – this is a normal process.Slide30

Rescue BreathingPlease review the steps below to perfect your rescue breathing technique:

1. Be sure the person’s airway is clear (check that nothing inside the person’s mouth or throat is blocking the airway2. Place one hand on the person’s chin, tilt the head back.3. Pinch the nose closed.4. Place your mouth over the person’s mouth to make a seal and give 2 slow breaths.

5. The person’s chest should rise (but not the stomach).6. Follow up with one breath every 5 seconds until the person can breath on their ownSlide31

WHY naloxone?Naloxone is an opioid overdose antidote.

Naloxone counteracts the effects of prescription opioids like hydrocodone, oxycodone, morphine, methadone and fentanyl and illegal opioids like heroin. Naloxone is safe. It is as nontoxic as water and has no potential for addiction. If a person has not taken opioids, naloxone will not hurt

them.Naloxone is cost effective. In Illinois anyone can be trained to administer naloxone. Slide32

2 Ways to Administer NaloxoneMost Common:

Nasal (intranasal – IN) Injectable (intramuscular – IM)

Extremely Expensive:Auto-injector(intramuscular – IM)Slide33

How to Give nasal spray Naloxone In the case of a known or suspected opioid overdose:Peel back the tab to remove NARCAN® Nasal Spray from its package.

Place the device into one nostril.Press the device plunger firmly.Get emergency help right away.Slide34

How to Give Injectable Naloxone Remove cap from Vial and uncover the needle

Insert needle through rubber plug with vial upside down. Pull back on plunger and take up 1mL

Slide35

How to Give Injectable Naloxone Inject 1mL of naloxone into upper arm, thigh, buttocks

If no reaction in 3 minutes, give second dose.Slide36

While you’re waiting for naloxone to kick in…Start rescue breathing again until you see the person start to breathe on their own.

Wait 2-3 minutes (longer if administering IN naloxone) to give the medication a chance to work.If no response after 2-3 minutes, give a second dose of naloxone and begin rescue breathing again.If still no response, continue rescue breathing until paramedics arrive and let them take over.

Note: naloxone will only work if the individual has taken an opioid. If they overdosed on a non-opioid, naloxone will not have an effect on them.Slide37

What to expect after administration of naloxone…Stay with the person for as long as you can or until help arrives

If the person is still unresponsive, make sure to lay them in the recovery position to prevent choking and wait for help. If the person is responsive, they will be confused about what is happening and will probably not remember overdosing. Explain what has happened

Comfort the person; withdrawal symptoms triggered by naloxone can feel unpleasant.Some people may become agitated or combative and will need help remaining calm.

Don’t allow the person to take more opioids, as they can overdose again.Slide38

Naloxone FactsOnset of action is about 2-3 minute

Duration of action is 30-120 minutes depending on method of administrationIt will not reverse an overdose caused by other drugs, only opioidsMay be used in children and pregnant womenNaloxone should be stored in its original packaging, while avoiding light, at room temperature.

It can be left in the car glove box overnight, but not as a permanent storage optionPay attention to the expiration date for any naloxone product. Most have an expiration date of about 12-18 months.

Expired naloxone can still be administered if there is no other alternative available. However, it may not be as effective and a second dose may be required. Slide39

Remember S.C.A.R.E.M.E.Slide40

Signs of withdrawalBody achesDiarrheaTachycardia

Fever, runny nose, sneezingPiloerection, Sweating,

YawningNausea or VomitingNervousness,

Restlessness or Irritability Shivering or Trembling, Abdominal Cramps, Weakness Increased Blood PressureSlide41

Summary – Do’s and Don’tsDO support the person’s breathing by administering naloxone or performing rescue breathingDO administer naloxone

DO put the person in the “recovery position” on the side, if the person is breathing independentlyDO stay with the person and keep him/her warmDON’T slap or try to forcefully stimulate the personDON’T put the person into a cold bath or showerDON’T inject the person with any substance

DON’T make the person vomit what he/she may have swallowedSlide42

Best way to locate Treatment Optionshttps://findtreatment.samhsa.gov/locator

SAMSHA Treatment Locator: Convenient and Easy to use Behavioral Health and Substance Abuse Treatment locator:Slide43

M.A.T. - Medication Assisted treatment

History: In the post- WWII there was a significant rise in the use of opioids. The federal government became concerned with the effects this was having on communities, so they began to increase punishment for possession and distribution. At this time the psychiatric community was finding that people addicted to opioids were much more likely to relapse despite the completion of detoxification and treatment programs. When this did little to quell the problem, the medical community began to advocate for opioid maintenance programs in which people dependent on opioids were given small doses under the care of a medical professional.

The initial interventions didn’t work because they used short half-life medications such as morphine. Patients quickly developed tolerance and needed increasing amounts of medication. Higher doses of morphine caused increased sedation and interfered with patients social functioning.

In response the federal government began funding experimental programs to use Methadone. Slide44

Forms of M.A.T.Methadone was the first successful medication used in conjunction with dependency treatment. It is a long acting agonist that is taken orally and binds with the opiate receptors. It stops withdrawal and craving while allowing the patient to function, and at appropriate dosing does not have any of euphoric or sedative effects. It is only available through approved treatment programs and is usually dispensed daily.

Buprenorphine/Naloxone combination medication contains buprenorphine (a partial agonist) and naloxone (an antagonist) designed to ward off attempts to get high through injection because if injected it can trigger withdrawal effects. In 2002 brand name Suboxone became the first form of MAT to be available by prescription from an office-based physician.

Long acting injectable naltrexone (Vivitrol) is the newest form of MAT. It is an antagonist that prevents the opioids to attaching to receptors, thus if a person takes an opioid any opioid effect is blocked. It is given monthly administered through a treatment program or office based physician. Slide45

Support for MAT is on a international scale. A 2014 briefing from SAHMSA lists the following as supporters of MAT:National Association of State Alcohol and Drug Abuse DirectorsWorld Health OrganizationNational Institute of Drug Court ProfessionalsNational Institute on Drug AbuseThis study also reviewed current literature to find the effectiveness of each type of MAT

Methadone- In 11 clinical trials of involving 1969 people, methadone improved retention and reduced use compared to non-medication treatment.Suboxone-SAHMSA reviewed clinical trials and saw that Suboxone was more effective than placebo, but not as effective as methadone.Vivitrol- A six month multi state study of people under legal supervision had “significantly fewer” positive urine tests.

effectivenessSlide46

NALOXONE FOR THOSE WHO NEED IT MOST NUMBER ONE priority: Put naloxone in the hands of those most likely to be on the scene and first to respond, individuals who use opioids, themselves.

How best to reach this population? By making naloxone available, in these settings: Syringe Exchange Programs Jails

Hospital Emergency Departments Free Clinics First RespondersFriends and Family membersMethadone, Suboxone and Other Treatment Programs Slide47

In Treatment – vulnerable PopulationPeople entering & exiting Treatment for Opiate Use Disorder

Effective January 1, 2017, all substance use treatment programs licensed by IDHS/DASA must provide educational information to clients identified as having or seeking treatment for opioid use disorder, including the use of a medication for the use of opioid use disorder, recognition of and response to opioid overdose, and the use and administration of naloxone (PA 99-0553).Ideally, each treatment program would:

Train each staff person/participant how to administer naloxoneEncourage each participant to access a dose of naloxone either through an outreach effort or with an insurance card at a pharmacy Slide48

Naloxone Kit LocationsWhere & Why?

1 in 5 Overdose Deaths Happen in Public

Bathrooms

Mount Kits in Highly visible area

Kits must be easily accessible

Naloxone kits are seen as another tool to be kept in the traditional “Emergency Kit” Slide49

Examples of Mounted KitsSlide50

dhs/dasa drug overdose prevention program (DOPP)Click here for Program Guideline Manual

Benefits of Enrolling

Be part of the effort to reduce opioid deaths in Illinois.

Gain access to innovative training;Stay informed about the most current legislation; Inform your community about naloxone and help save lives!Slide51

IDHS/DASA Drug Overdose Prevention Program (DOPP)Voluntary Registration Steps On DHS/DASA Website recover DASA Drug Overdose Drug Program Implementation Guideline from :

http://intranet.dhs.illinois.gov/oneweb/page.aspx?item=58142Fill form IL444-2051 Enrollment form

EMAIL form IL444-2051 and Naloxone Training Slideshow/Training Module to DHS.DOPP.Coordinator@illinois.gov *Upon review and consideration an acceptance letter and certificate will be issued out to the Program Director (valid for

five (5) years) Note: All updates or changes to the enrolled agency (i.e. change of Program Director, Address, Phone Number) must be submitted to DHS.DOPP.Coordinator@illinois.gov within 30 days of the change.

Within 30 days of enrollment expiration, an email will be sent to the Program Director to renew enrollment with the Illinois Drug Overdose Prevention ProgramSlide52

Program administrationIdentify a physician, physician assistant, or advanced practice nurse to oversee the clinical aspects of the Drug Overdose Prevention Program ;Establish the content of a training program, which is consistent with the SAMHSA toolkit and IDHS/DASA policies and procedures ;

Maintain and review Drug Overdose Prevention Program records including quarterly training records, inventory of supplies and materials, and reversal forms

The Program Director Will:Slide53

Program administration (cont)The Health Care Professional Will

:Serve as a clinical advisor and liaison concerning medical issues related to the Drug Overdose Prevention Program;Provide consultation to ensure that all trained Overdose Responders are properly trained;

Adapt and approve training program content and protocols;Provide liaison with local emergency medical services and emergency dispatch agencies, where appropriate;Review reports of all administration of an opioid antagonistSlide54

Section 1DOCUMENTATION

Naloxone Administration Reporting Form

THIS FORM IS TO BE COMPLETED WITHIN FIVE (5) BUSINESS DAYS

OF NALOXONE ADMINISTRATION.Slide55

Condition of PersonSlide56

Standing OrderSlide57

Training Curriculum & MATERIALSDescribe the qualifications of individuals who can provide the drug overdose prevention training ( including the use of naloxone) to potential responders;

Describe the duration and frequency requirements to training;Describe any required supervision or monitoring of drug overdose responders and program trainers;Use available reference material to enhance training content;

Describe the training oversight responsibilities of the program’s official designee and HCP. Utilize resource materials on DHS/DASA website – DOPPDOPP webinar and slides are welcomed to be copiedSlide58

Contact InformationDrug Overdose Prevention Program email:DHS.DOPP.coordinator@illinois.gov

(email all forms to this email)Seth Eisenberg, M.D.Seth.Eisenberg@illinois.gov

Rosie GianforteRosie.m.gianforte@illinois.gov312-814-2136Slide59

HELPFUL VIDEOS - Highlight link AND CLICK Anatomy of an Overdose

https://www.youtube.com/watch?v=DhS9M2ni2yEAdministering Nasal Atomizer Naloxone Bystander video

http://adaptpharma.com/news-events/press-kitAdministering

injectable naloxonehttps://vimeo.com/197652566/ce41306803https://vimeo.com/197650414/4916741e17 (Spanish)

R

ecognizing

an overdose & Reversing an

overdose

https://

www.youtube.com/watch?v=FZpgjRBby_M

M.A.T. Treatment

https://

youtu.be/ht7EpK2UF4ISlide60

Helpful websites….News

+ research on overdose preventionPrescribetoprevent.orgGetNaloxoneNow.org

preventionalliance.org

Opioid overdose prevention educationStopoverdose.orgFamily supportGRASP

: Grief Recovery After a Substance Passing

Grasphelp.org

Learn2cope.org

Publications and Resources

Law Enforcement Naloxone Toolkit at the Bureau of Justice Assistance’s National Training and Technical Assistance Center (link is external)

Naloxone Injection at MedlinePlus

Opioid Overdose Prevention Toolkit –

2014