Microorganism or Microbe 1 Small living organism 2 Not visible to the naked eye 3 Must be viewed under a microscope 4 Found everywhere in the environment including on and in the ID: 779675
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Slide1
Principles of Infection control
Slide2Microorganism or Microbe
1. Small
living organism2. Not visible to the naked eye3. Must be viewed under a microscope4. Found everywhere in the environment, including on and in the human body
Slide3Many microorganisms are part of
normal flora
of the body; flora is microbial organisms in environment such as the intestinal, vaginal, oral, or urinary systemsa. Beneficial in maintaining certain body processesb. Called nonpathogens
Slide4Other microorganisms cause
infection
and diseasea. these are called pathogens or germs At times, a microorganism that is beneficial in one body system can become pathogenic in another body systema. Bacteria called Escherichia coli (E. coil) is part of the natural flora of the
large intestine
b. If E. coli enters
urinary system
, it causes an
infection
Slide5Classification of Microorganisms
Bacteria
a. Simple one-celled plants that multiply rapidlyb. Classified by shape and arrangementc. Some diseases caused by bacteria: (1) meningitis (2) gonorrhea (3) boils
(4) wound infections
(5) typhoid
(6)
syphilis
Slide6Congenital Syphilis
Primary Syphilis
Secondary Syphilis
Slide7Boils
Slide8Antibiotics
are used to kill bacteria Some strains of bacteria have be come antibiotic-resistantMeans that the antibiotic is no longer
effective
against the bacteria
MRSA
Slide9Protozoa
a.
One-celled animal-like organismb. Often found in decayed materials and contaminated waterd. Some protozoa are pathogenic and cause diseases such as:(1) malaria(2) amebic dysentery trichomonas
(3)
African sleeping sickness
Slide10Malaria
African Sleeping Sickness
Slide11Fungi
Simple
plantlike organismsLive on dead organic matterYeasts and molds are two common forms of fungi that can be pathogenic Cause diseases such as:(1) ringworm
(2) athlete’s foot
(3)
histoplasmosis
(4) yeast vaginitis
(5)
thrush
Athlete’s Foot
Thrush
R
ingworm
Slide13Antibiotics
do not kill fungi
Antifungal medications are available for many of the pathogenic fungiThese medications are expensive, must be taken internally for a long period of time, and may cause liver damage
Slide14Rickettsiae
Parasitic
microorganisms (1) Cannot live outside the cells of an other living organism(2) Commonly found on fleas, lice, ticks, and mites(3) Transmitted to humans by the bites
of these insects
Cause
diseases such as:
(1)
typhus fever
(2) Rocky Mountain spotted fever
Antibiotics
are
effective
against many different
rickettsiae
Slide15Rocky Mountain spotted fever cycle
Typhus lesion
Fleas, Ticks, Lice
Slide16Viruses
Smallest
microorganisms, visible only in an electron microscopeCannot reproduce
unless they are
inside another living cell
Spread
from
human
to human by
blood
and
body
secretions
Slide17Very difficult to
kill
(1) Resistant to many disinfectants(2) Not affected by antibioticsCause many diseases such as:(1) common cold(2) measles(3) mumps(4) chicken pox
(5) herpes
(6)
influenza
(7)
polio
Slide18Chicken pox
Measles
Herpes
Mumps
Slide19Three diseases of major concern to health care workers
(1)
Hepatitis B or serum hepatitis Caused by the HBV virusTransmitted by blood serum and body secretions Affects the
liver
and can lead to
destruction and scarring
of liver cells
Vaccine
has been developed to protect individuals from this disease
Vaccine
is expensive and involves a series of three injectionsUnder
federal law,
employers
must provide the vaccination at no
cost
to any
health care
worker with occupational exposure to
blood
or other
body
secretions
Individual
does have the right to refuse the vaccination, but a
written
record must be kept proving that the vaccine was offered
Slide20(2)Hepatitis C
Caused
by the hepatitis C virus, or HCVTransmitted by blood and blood containing body fluidsMany individuals who contact the disease are asymptomatic (display no symptoms)Others have mild symptoms that are often diagnosed as
influenza or flu
HCV
can cause
serious liver
damage
At
present there is no preventive
immunization
, but a vaccine is being developed
Both
HBV and HCV are extremely difficult to destroyViruses
can even remain
active
for
several days in dried blood
Health
care workers must take every
precaution
to protect themselves from
hepatitis viruses
(3) Acquired immune deficiency syndrome (AIDS)
Caused
by the HIV (Human Immunodeficient Virus)Suppresses the immune systemIndividual cannot fight off many cancers and infections that would not affect a healthy personNo cure at present and no vaccine available
Slide22Factors required for Growth:
1. Microorganisms need certain things to grow and reproduce
2. Most microorganisms prefer a warm environment, and body temperature is ideal3. Darkness is also preferred by most microorganisms, and many are killed quickly by sunlight4. Source of food and moisture is needed5. Need for oxygen variesa. Aerobic organisms
require oxygen to live
b.
Anaerobic
organisms
live and reproduce in absence of oxygen
6. Human body is ideal supplier of all of the requirements
How do pathogenic organisms cause disease?
Pathogenic
microorganisms cause infection and disease in different ways:1. Some pathogens produce poisons, called toxins, which harm
body
a. Example is
bacillus tetanus
b. Produces toxins that damage
central nervous system
Slide242. Some pathogens cause an
allergic
reaction resulting in a runny nose, watery eyes, and sneezing3. Other pathogens attack and destroy the living cells they invadea. Example is the protozoan that causes malariab. Invades
red blood cells
and causes them to
rupture
Slide25Classifications of Diseases and Infections
Classified
as endogenous, exogenous, nosocomial, and opportunisticEndogenous1) Means the infection or disease originates within the body2). Includes metabolic disorders,
congenital
abnormalities,
tumors
, and infections caused by microorganisms within the body
Slide26Exogenous
1
) Means that the infection or disease originates outside the body2) Examples include pathogenic organisms that invade the body, radiation, chemical agents, trauma, electric shock, and temperature extremes
Slide27Nosocomial
1)
Infections acquired by an individual in a health care facility, such as a hospital or long-term care facility2) Usually present in facility and transmitted by health care workers to the patient3) Many of the pathogens transmitted in this manner are antibiotic-resistant
4) Can
cause a
serious and even life-threatening
infection
5) Common
examples:
(a) Staphylococcus
(b) Pseudomonas
(c) Enterococci
6) Infection
control programs are used in health care facilities to prevent and deal with
nosocomial
infections
Slide28Opportunistic
1) Infections
that occur when the body’s defenses are weak2) Diseases do not usually occur in individuals with an intact immune system3) Examples include the development of Kaposi’s sarcoma (a rare type of cancer) or Pneumocystis carinii pneumonia in individuals with
AIDS
Slide29Common Body Defenses
1.
Mucous membrane that lines the respiratory, digestive, and reproductive tract and traps pathogens2. Cilia (tiny, hairlike structures) lining the respiratory tract to propel pathogens out of the body3. Coughing and sneezing
4.
Hydrochloric acid
in the stomach to destroy pathogens
5.
Tears
in the eye that contain
bacteriocidal
(killing bacteria) chemicals
6.
Fever
7. Inflammation resulting in leukocytes
or white blood cells
destroying
pathogens
Slide308.
Immune response
a. Body produces antibodies, protective proteins that combat pathogensb. Cells secrete protective chemicals such as interferon
Slide319. Human becomes susceptible host in some instances
a. Large numbers of the pathogen invade the body
b. Body defenses are weak10. Ending the chain of infectiona. If any part of the chain can be eliminated, the spread of disease or infection will be stoppedb. Follow practices to interrupt or break this chainc. Prevent the transmission of diseased. Important to remember that pathogens are everywheree. Preventing pathogen transmission is a continuous process