Simon Gilbody Professor of Psychological Medicine amp Psychiatric Epidemiology University of York January 2023 Chipping away at this question for 15 years What works for people with SMI ID: 1035709
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1. Implementation gap:how long have we known that interventions workSimon Gilbody Professor of Psychological Medicine & Psychiatric EpidemiologyUniversity of YorkJanuary 2023
2. Chipping away at this question for 15+ yearsWhat works for people with SMI?
3. behavioural support + meds = double chances of quittingClinical trialsEvidence synthesesA large pragmatic trial for ppl with SMI
4. The same things work in SMI as for everyone else
5. Level 1 evidence, based on systematic reviews, on the effectiveness of:NRTBupropionVarenicline (when it becomes available)Behavioural support, following NCSCT & SCIMITAR model
6. Q: When should we have known this?Q: How does this new trial change the story?Useful for policy analysisCumulative meta-analysis
7. When should we have known this? Cumulative meta-analysis of 25 trials& linkage to key policy initiatives
8. A cumulative analysis of all trials
9. A cumulative analysis of all trials
10. A cumulative analysis of all trials
11. NRTBupropionVarenicline (when it becomes available)Behavioural support, following NCSCT & SCIMITAR model
12. The SCIMITAR trial was funded by the National Institute for Health Research (NIHR) Health Technology Assessment (HTA) Programme (project number 07/41/05). The views and opinions expressed by authors do not necessarily reflect those of the National Health Service, NIHR, the NIHR Evaluation, Trials and Studies Coordinating entre, the HTA Programme, or the Department of Health. Disclaimer