Holistic Health Integrative medicine as a new direction in health care - PowerPoint Presentation

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Holistic Health

Integrative medicine as a new direction in health care

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Holistic Health: primary care for the 21

st

century

The word ‘health’ means ‘whole’, from the Old English

hale

; something that should bring a rejuvenating wholeness to one’s body, mood and mind.

Holism

encompasses all safe modalities of Diagnosis and T/T while emphasizing the whole person : physical, mental, emotional and spiritual.

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Alternative therapies

Complementary therapies

Conventional medicine

CAM assumes that the real power for healing comes from within, rather than outside of , the self.

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Integrative Medicine

Is evolving as a new direction in health care.

Combines the concepts and practices of conventional and alternative medicine.

It focuses on:

Health promotion, disease prevention and Illness care

Defining character. Of Health promotion: It goes beyond alleviation of specific illness to maximize overall health.

Use of broader measures, regular relaxation or meditation reduces risk of cardiovascular disease and increases general wellbeing over a longer term

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Types of therapies

Allopathic or Western medicine

Ayurvedic

medicine

Chiropractic

Environmental medicineHerbal medicineHolistic dentistryHomeopathyNaturopathic medicine

Osteopathic medicineShamanismTraditional Chinese medicineMind-Body therapies

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Naturopathic Medicine

Naturopathy

:1895 : John

Scheel

Latin word

natura with Greek word pathos to signify a method of healing that was natural in scope.1930s, at which time its practice waned, due to the emergence of antibiotic drugs

.It emphasizes the curative power of nature and in the body’s ability to heal itself. Our body is designed to heal itself from underlying imbalances.Develop “a taste for nature

”: A naturally healthy diet requires a daily dose of nature itself. Getting outside and soaking up the sunshine and fresh air may be practically prescribed as a wonder drug. The importance of sunlight in regulating our happiness and hormone levels, and the modern dangers of ‘sick building syndrome

’: People who stay cooped up indoors, by contrast, ultimately suffer mysterious slumps to their overall wellbeing.It uses many natural therapies: Nutrition, herbal medicine, hydrotherapy, acupuncture, homeopathy, therapeutic massage and oriental medicine

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Establish health and wellness.

Ultimate goal of NM is to help patients achieve and maintain optimal

health

and

wellness

.Naturopaths regard

health as a state of optimal well-being in body, mind and spirit, while defining “wellness”

as a state of positive thoughts, attitudes, beliefs, and emotions.

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Herbal medicine over pharmaceutical medicine

Herbs are more natural, gentler and less toxic

Multiple benefits while drugs several side effects

Activity and therapeutic effects of a plant results from combined actions of many constituents working together.

Some constituents may “ buffer” some otherwise harmful side effects.

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EFFECT OF CANNABIDIOL ON HUMAN PROSTATE CANCER.

∆

9

-tetrahydrocannbinol (THC)

Cannabidiol (CBD)

Cannabinol (CBN)

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Potential therapeutic properties of

Cannabis sativa

BUT its pharmaceutical application is limited by their euphoric and other psychoactive effects

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-

Renewed interest due to diverse pharmacologic activities such as : cell growth inhibition, anti-inflammatory effects and tumor regression.

-To date, cannabinoids have been successfully used in the treatment of nausea and vomiting, two common side effects that accompany chemotherapy in cancer patients.

-Several plant-derived (

THC and CBD

) synthetic (

WIN-55, 212-2 and HU-210

) and endogenous cannabinoids

(anandamide and 2-arachidonoylglycerol) are now known to exert anti-proliferative actions on a wide spectrum of tumour cells in culture

Most non-THC plant cannabinoids e.g. cannabidiol and cannabigerol are considered to be non-psychotropic. However, the precise pathways through which these molecules produce an antitumor effect have not been yet fully characterized.

Cannabinoids, the active components of

Cannabis sativa

CBD

THC

CBN

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In Vitro Anticancer Activity of Plant-Derived Cannabidiol

on Prostate Cancer Cell Lines: Pharmacology & Pharmacy, 2014, 5, 806-820

 

-

Expression level of both cannabinoid receptors, CB1 and CB2, are significantly higher in human prostate cancer cell lines.

-High CBD Cannabis extracts are cytotoxic to androgen responsive LNCaP cells- Induction of cytotoxicity: Decrease in expression of androgen receptor, PSA and Proliferation cell nuclear antigen (PCNA)

CBD enriched cannabis extract may effectively inhibit spheroid formation in cancer stem cells.Anti-inflammtory property of CBD- ↓ IL-6 & IL-8

- Anti-carcinogenic activity of a non-habit forming cannabinoids (cannabidiol, cannabigerol, and

cannabichromene) lack psychotropic activity could be used as novel therapeutic agent for the treatment of prostate cancer.

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Our Case studies confirmed cannbidiol

efficacy in reducing muscle spasticity and pain levels over a 12 month period.

CR 1:

Standardized natural product cannabis in pain management and

observations at a Canadian compassion society: a case report ;

Cases Journal 2009, 2:7487CR 2: Standardized cannabis in multiple sclerosis: a case report ; Cases Journal 2010, 3:7

CR 3 : Cannabis Responsive Head Injury Induced Multiple Disabilities: A Case Report; Pharmacology & Pharmacy, 2012, 3, 58-61

47 year old Caucasian had minor subdural hematoma and focal subarachnoid haemorrhage following a physical assault. His impairments included cognitive slowing with decreased short term memory, organized skill & language deficit. He had spastic gait (hemiplegic), VII nerve palsy, mild cerebellar

dysfunction, blurred vision and easy fatigue. He was unable to return to work or drive. In addition to cognitive deficit, right hemi paresis & dizziness; he had symptoms of anxiety & depression. Within 6 months all his symptoms abated. His cognitive functions, memory, vocabulary and gait became increasingly better day by day with continued use of cannabis.

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Cancer stem cells contributing to drug resistance and tumor recurrence

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LNCAP control

Prostaspheres

2

wks

Cannabinoids suppress

LNCaP

spheroid formation

ng/ml

CBD

20

CBN

0.4

THC

10

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Mind-body therapies

The term

body-mind

emerged when practitioners realized that the body affects the mind and visa-versa.

Mind-body treatment:

Psychotherapy, Art therapy, Music/sound Therapy, Imagery, Hypnosis, EFT and Meditation.

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FIGHT-OR-FLIGHT RESPONSE

Two switches

on body’s involuntary nervous system: 1.

ordinary daily event switch

, controls the normal processes of body e.g. breathing, digestion, and metabolism.

2. The

emergency switch

designed to survive stress response, “

fight-or-flight response. In nature this type of response helps animals release adrenalin and flee or attack prey

Keep in mind that your body’s stress response is meant for short term use only.

If it is triggered too often, and if it stays on for too long, one can develop

serious health problems.

Too much worry cause stress hormones to be released unnecessarily into the blood stream that affects circulatory system, immune system, respiratory , digestive and urinary organs, bones muscle and skin

Stress

Management:

Deep

breathing, muscular relaxation, visualization, note taking, Regular Exercise

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Energy medicine and aura fields

Energy and aura theory is based on the belief that energy fields surround the physical body.

Oriental meridian theories

Indian science of chakras.

Purpose: open blocked channels and realign the unbalanced energy system

Therapeutic touch, healing touch, aura healing, chakra opening or closing, electromagnetic healing

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Electro-photonic Kirlian glow around a human fingertip recorded using solid state

computerised

Gas Discharge

Visualisation

(GDV)

camera. View

from underneath, through a semi-transparent glass electrode that provided electrical field excitation.

Kirlian effect

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Layers of Aura

Chakras are components of an aura and each interpenetrates the other.

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Chakras

Chakra means

Wheel

in Sanskrit.

Chakras are spinning

energy centers that look like spinning wheels

Chakras

are linked to sound, light and color.

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To heal, is to bring the chakras into alignment and balance

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EARTH CHAKRA SYSTEM

The Earth, as a living organism, has chakra centers.

They link with major grid points [meridians] based on sacred geometry.

Our chakras are aligned to the Earth's grid system.

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LOVERS

Lovers connect through their chakra systems

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1696:The first western reference on

chakras

,directly refers to inner force

centres

.

Some authors say that there is relationship between positions and functions of

chakras

and various organs of endocrine system and nerve ganglia along spinal cord, bringing two different systems to systemize insights about the same phenomenon.

Physical manifestation as Endo. Glands

Subjective manifestation as the associated emotional, mental and spiritual experience.

Western derivative models and interpretations

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Emotional Freedom Techniques

Emotional health is the foundation beneath self confidence and self confidence is the springboard to achievement in every walk of life.

EFT is an

emotional version of acupuncture

except needles aren't necessary.

Instead, you stimulate well established energy meridian points on your body by tapping on them with your fingertips. The process is easy to memorize and is portable so you can do it anywhere.

"The cause of all negative emotions is a disruption in the body's energy system.“And because our physical pains and diseases are so obviously connected with our emotions the following statement has also proven to be true...

"Our unresolved negative emotions are major contributors to most physical pains and diseases."

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"The cause of all negative emotions is a disruption in the body's energy system.“

And because our physical pains and diseases are so obviously connected with our emotions the following statement has also proven to be true...

"Our unresolved negative emotions are major contributors to most physical pains and diseases."

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“The cause of all negative emotions is a disruption in the body’s energy system

How a negative emotion is caused

Step 1

Distressing

Memory

Step 2

The Intermediate Step

“zzzzzt”

A disruption in the

body’s energy system

Step 3

Negative

Emotion

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Healing Meditation : focus the mind and heal the

body

-Science

has proven, beyond doubt, that the contents of our thoughts and emotions directly and immediately influence our biochemistry.

-Your

body possesses the innate capacity to heal itself. Your body can manufacture and administer the precise balance of neurochemicals that can reverse illness and cure disease. -You can consciously influence and direct the body's output of health chemical information through meditation and visualization techniques

.-Believe in your power and anything is possible. The power of faith is what miracles are made of. -Faith bridges the gap between mind and matter, between self and Higher Powers. Through faith we have direct access to the source of creation, where beliefs become reality and needs are met in extraordinary ways.

-Meditation balances right and left hemispheres of the brain to produce the remarkable mental state known as Hemispheric Synchronization. It impact the body at a cellular level. -Cumulative benefits of meditation include: Improved ability to concentrate, increased creativity, greater clarity of thought, enhanced access to emotions and heightened states of well being

.-Scientists have found that when the brain is generating large amounts of delta waves the pituitary gland triggers the release of HGH, Human Growth Hormone, which is vital for healing.

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With guided meditation mind absorbs information at both the conscious ( beta level) and inner- conscious levels ( alpha and theta levels)

-Meditation induce

altered states of deep relaxation

-Alpha and Theta have

long been acclaimed as the brain state of heightened creativity and deep relaxation

.

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Positive thoughts produce positive results. The only problem is that some of our most persistent,

self-defeating

beliefs are stored deep in the unconscious, where they have the power to undermine

our happiness

and sabotage our success.

Now you can effortlessly change those negative beliefs to produce the results you want.Subliminal

messages are deeply absorbed by the unconscious to immediately impact your sense of self,your creativity and the dynamic expression of your power in the world.

Subliminal MessagesP O S I T I V E T H I N K I N GI am optimistic

I trust lifeI feel great, I love my lifeMy life worksI am clear and lucid

I achieve my goals with easeAll that I seek is seeking meI get all the help I needI am attractive, active

and in demandI adjust effortlessly

I am confident

I accept challenges

Positive solutions abound

I am enthusiastic

I am lucky

I feel positive energy

flowing

through me

I am safe, I am free

I trust life to bring me the best

My hopes and dreams come true

I love my life

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Natural Killer Cells for Prostate Cancer Immunotherapy,

May 14,

2019PCF-funded investigator Dr. Aaron LeBeau

of the University of Minnesota and his

team

https://www.pcf.org/news/natural-killer-cells-for-prostate-cancer-immunotherapy/NK cell (pink) attacking tumor cell (green)

How do NK cells work? These cells are like beat cops on patrol, traveling around the body to look for and kill cells

infected with a virus, bacteria, and cancer cells.Once they recognize a foreign or dangerous cell, they release toxic payloads of enzymes that make holes in the target cell, enter that cell, and digest its proteins, killing it. However, NK cells don’t run amok. They receive both activating (go!) and inhibitory (stop!) signals; whether they actually deploy depends on the balance of these signals.

Scientists are now using a new type of immunotherapy using a specific type of immune cell called natural killer cells, or

NK cells.

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NK cells have several potential advantages vs other types of immunotherapy.

-A single patient requires an infusion of ten billion NK

cells that can

easily be isolated from blood and grown in the lab

. -Nor do they require donor matching, as used for blood transfusions, so a single donor could, in theory, provide NK cells for many patients. -NK cell treatments can be significantly cheaper

than other immunotherapies that must be made from a patient’s own cells. -NK cells live for about a week in the body, so they won’t “hang around” too long, possibly causing adverse effects. What’s the catch?

-NK cell therapies still face some hurdles, such as a lack of “targeted” action – they don’t necessarily go to where they are needed. -Tumors can also influence the environment immediately around them and suppress the immune system locally.

Natural Killer Cells for Prostate Cancer Immunotherapy: safe and effective new treatments in the future.

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Natural Killer Cells for Prostate Cancer Immunotherapy

One way to

overcome the problem of tumors hiding from the immune system

is to

attach a “targeting device” to the NK cell, such that it would recognize prostate cancer cells and not normal tissue; “chimeric antigen receptor,” or CAR for short, to accomplish tumor targeting.  The CAR is a genetically engineered protein that recognizes a particular protein on the surface of prostate cancer cells and activates the NK cell to kill the tumor

cellSupported by a PCF Challenge Award, the project will move to testing in animal models this fall. It may be possible to start clinical trials in four years.

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N

on-pharmacological

modes of treatment such as meditation and Yoga have been considered as alternative approaches to treat neurological

disorders. e.g.

Alzheimer’s Disease Nerve growth factor (NGF), involved

in the development, maintenance and survival of the peripheral and the central nervous systems, is significantly reduced in AD patients Saliva is a known source of NGF, and incidentally, Yoga and relaxation stimulate salivation.

Yogic breathing (YB, also called Pranayama) is a collection of techniques to regulate breathing voluntarily.

YB induces a strong relaxation response via vagal and parasympathetic stimulation .

Such responses are causally linked to rapid changes in gene expression, particularly to those genes controlling stress, inflammation, and metabolism.

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Regular physical activity coupled with proper nutrition and adequate sleep promotes health.