December 23 2019 President and Chief Executive Officer PDS Biotechnology Corporation 303A College Road East Princeton NJ 08540 Re PDS Biotechnology Corporation Registration Statement on Form S1 Fi ID: 847969
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1 December 23, 2019 Frank K. Bedu-Addo, P
December 23, 2019 Frank K. Bedu-Addo, Ph.D. President and Chief Executive Officer PDS Biotechnology Corporation 303A College Road East Princeton, NJ 08540 Re: PDS Biotechnology Corporation Registration Statement on Form S-1 Filed December 17, 2019 File No. 333-235549 Dear Dr. Bedu-Addo: This is to advise you that we have not reviewed and will not review your registrationstatement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind youthat the company and its management are responsible for the accuracy and adequacy of theirdisclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Sincerely, Division of Corporation Finance Office of Life Sciences cc: Fahd. M.T. Riaz, Esq.