Drug Overview Antivirals Antiherpes acyclovir famciclovir valacyclovir Antivirals Antiinfluenza General antiviral Neuraminidase inhibitors Antiprotozoal metronidazole tinidazole ID: 914615
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Slide1
Chapter 68
Antivirals and Antiprotozoal Agents
Slide2Drug Overview
Antivirals
–
Antiherpes
acyclovir, famciclovir, valacyclovir
Antivirals
–
Antiinfluenza
General antiviral
Neuraminidase inhibitors
Antiprotozoal
metronidazole
tinidazole
chloroquine
Slide3Drug Overview
Indications
acyclovir, famciclovir, valacyclovir, and penciclovir
amantadine, rimantadine
zanamivir, oseltamivir
metronidazole, tinidazole
chloroquine
Slide4Mechanism of Action
Antivirals
acyclovir and famciclovir
amantadine and rimantadine
zanamivir and oseltamivir
Antiprotozoals
metronidazole
chloroquine
Slide5Treatment Principles
Standardized Guidelines
See World Health Organization, www.worldhealth/int
Evidence-Based Recommendations
Cardinal Points of Treatment
Herpes simplex and zoster
Antiinfluenza
Antiprotozoals
Slide6Treatment Principles
Pharmacologic Treatment
Herpes simplex treatment
Herpes zoster treatment
Antiinfluenza drugs
Antiprotozoal drugs
metronidazole
chloroquine
Slide7Treatment Principles
How to Monitor
Antivirals
Antiprotozoals
Patient Variables
Geriatrics
Pediatrics
Pregnancy and lactation
Slide8Treatment Principles
Patient Education
Antivirals
Antiherpes agents
amantadine, rimantadine
zanamivir
Antiprotozoals
metronidazole
chloroquine
Slide9Antivirals
acyclovir (Zovirax), famciclovir (Famvir), valacyclovir (Valtrex)
Contraindications
Warnings
Precautions
Pharmacokinetics
Adverse effects
Drug interactions
Dosage and administration
Slide10Antiinfluenza Agents
amantadine (Symmetrel), rimantadine (Flumadine)
Contraindications
Warnings
Precautions
Overdosage
Slide11Antiinfluenza Agents
zanamivir (Relenza), oseltamivir (Tamiflu)
Contraindications
Warnings
Precautions
Dosage and administration
Slide12Antiprotozoal Agents
zanamivir (Relenza), oseltamivir (Tamiflu)
Contraindications
Warnings
Precautions
Pharmacokinetics
Drug interactions
Overdosage
Dosage and administration
Slide13Antiprotozoal Agents
chloroquine (Plaquenil)
Contraindications
Warnings
Dosage and administration
Adverse effects
Overdosage
Precautions