PPT-Mass Spectrometry

Author : stefany-barnette | Published Date : 2016-07-17

Andrew Rouff and Ben Berger A Brief History 1897 JJ Thomson recorded first masstocharge ratio of electrons 1951 W Pauli and H Steinwedel developed first quadrupole

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Mass Spectrometry: Transcript


Andrew Rouff and Ben Berger A Brief History 1897 JJ Thomson recorded first masstocharge ratio of electrons 1951 W Pauli and H Steinwedel developed first quadrupole mass spectrometer 1959 K Biemann applies electron ionisation mass spectrometry. Jeff Johnson. Feb 19, 2014. MS Proteomics in a Nutshell. Ionization. Delivering macromolecules to the MS. Ion Manipulation. Trapping and ejecting . analytes. of interest. Fragmentation. Breaking apart for more information. Protein Extraction. Mechanical grinding. Detergents. Other buffers. Sonication. http://www.piercenet.com/browse.cfm?fldID=FA97D803-6953-48E4-A7BD-6947D35FE83B. Considerations for mass spectrometry. Salts and buffers in high concentrations can cause ion suppression and adduct formation in electrospray mass spectrometry. Outline. Tandem Mass Spectrometry. De Novo Peptide Sequencing. Spectrum Graph . Protein Identification via Database Search. Identifying Post Translationally Modified Peptides . Spectral Convolution . Science Afternoon at NIST. February 4. th. , 2013. Questions Analytical (Bio)Chemists Ask. Environmental. Is the water safe to drink?. Deepwater. Horizon Oil Spill: Where did the oil go? When will the seafood be safe to eat again?. H.V.Florance@exeter.ac.uk. bs-mass-spec@exeter.ac.uk. http://biosciences.exeter.ac.uk/facilities/spectrometry/. The University of Exeter Science Strategy. – Systems Biology. HOW MASS SPECTROMETRY CAN IMPROVE YOUR RESEARCH. Know what information they can provide. Interpret simple mass spectra graphs. Know some uses of mass spectrometry. A mass spectrometer….. Draw the mass spectrometer. Describe the 5 step process. AS A CARTOON STORY BOARD!. Jonathan A. Karty, Ph.D.. jkarty@indiana.edu. http://msf.chem.indiana.edu . Why Mass Spectrometry. Information is composition-specific. Very selective analytical technique. Most other . spectroscopies. David Horn. Thermo Fisher Scientific . San Jose, CA. Outline. Challenges in the characterization of biopharmaceuticals. Introduction to the new generation of . Orbitrap. TM. . mass spectrometers. Confident intact antibody analysis using the Q . Fenyő. Readings for Today. http://fenyolab.org/pi2019. Ion Source. Mass Analyzer. Detector. mass/charge. intensity. Mass spectrometry . Mass Analyzer 1. Frag-mentation. Detector. Ion Source. Mass Analyzer 2. ALONG WITH . H/D. EXCHANGE TO CHARACTERIZE . ANTIPLATELET DRUG DEGRADATION PATHWAYS.. A case report. .. B. ernard Do*, . Fatma . Amrani. , . Philippe-Henri . Secrétanand. . Najet. . Yagoubi. *Hospital Pharmacist . &. Secondary. . ion. . mass. . spectrometry. (SIMS). L. Seda Mut 20970802 . Neslihan . Ötük. 20622809. Beytepe. Ankara. 12.04.2012. Outline. Historical Background of MS. . and. SIMS. What is M. Does Agilent Have the Answer. ?. Ashley Sage PhD. What is Mass Spectrometry?. A powerful analytical chemistry technique that is used to:. elucidate the structure and chemical properties of molecules. Mass Spectrometry deals with the examination of characteristics fragments and arising from the breakdown of organic molecules. The mass spectrum is the plot of relative intensity of the ions agains #Certification #Dumps #Certification_exam_Dumps
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