What are nucleic acid Linear polymers of nucleaotidesfirst isolated by Miescher 1871 Each nucleotide consist of 3 components 1 purine or pyrimidine nucleobase ID: 1014116
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1. Nucleic acids Definition and classification
2. What are nucleic acid ?Linear polymers of nucleaotides.first isolated by Miescher (1871)Each nucleotide consist of 3 components 1. purine or pyrimidine nucleobase 2. Pentose sugar 3. Phosphate groupNucleic acids are deoxyribonucleic Acid(DNA) and ribonucleic acid(RNA)
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5. Types of RNAIn all prokaryotic and eukaryotic organisms ,three main classes of RNA molecules exist: Messenger RNA (m RNA) Transfer RNA (t RNA) Ribosomal RNA (r RNA)
6. mRNAmRNA is translated from DNA in the nucleus and posted out to the ribosomes for translation. Codons are complementary to DNA triplets specifies one amino acid.mRNA is single stranded.Accounts for only 5% of total RNA.5’ end is capped with guanosine triphosphate nucleotide While 3’ end has ply-A tail.
7. rRNArRNA are found in the ribosomes and account for 8O% of total Rna in cell.Ribosome consist of large subunit called the 50S and small subunit called 30S. Ribosomes are the site for protein synthesis.It is also single stranded but may be variously folded and show complementary base pairing at fold.
8. tRNAtRNA is the smallest of the 3 types of RNA It is an essential component of translation : transfer of amino acids during protein synthesis.Each of 20 amino acids have specific tRNA.tRNA have a clover leaf like structure which is stabilized by strong H- bond between nucleotides. Hair pin model : Hoagland Clover leaf model: Holle