Extracellular Vesicle PMID 23420871 Extracellular Exosome or exosomes plural Formed in multivesicular bodies 40200 nm PMID 6151502 16487731 15261674 20601276 ID: 438178
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Vesicle
Extracellular Vesicle(PMID: 23420871)
Extracellular Exosome or “exosomes” (plural) Formed in multivesicular bodies~40-200 nm(PMID: 6151502 , 16487731, 15261674, 20601276)
Microvesicle Vesicle budding directly from plasma membrane~50-1000 nm(PMID: 21039423, 19144520)
Apoptotic vesicleExtracellular vesicle from apoptotic/necrotic cells~50-5000 nm(PMID: 24223256, PMID: 15242875)
Membrane-bounded Vesicle
Cellular Component
Organelle
Extracellular region
Extracellular organelle
Extracellular region part
Extracellular RNP
(PMID:
21383194)
Membrane-bounded Organelle
Extracellular Membrane-bounded Organelle
RNP
Intracellular RNP
Macromolecular complex
Cell part
Intracellular part
Extracellular vesicular
exosome
(synonym
)
Microparticle
Apoptotic bleb,
apoptotic body (synonyms)
Ectosome
(PMID: 21039423
)
Remove (replace with EV)
Shedding Microvesicle
(PMID:
19144520
)
Exosome
(
RNAse
complex)
Protein complex
cytoplasm
Cytoplasmic
exosome
(
RNAse
complex
)
Intracellular organelle
Intracellular membrane-bounded organelle
nucleus
Nuclear
exosome
(
RNAse
complex
)
Legend
Black: terms and relationships existing in GO
Red: terms and relationships proposed by ERCC/ISEV
Blue: existing terms and relationships that ERCC/ISEV propose to remove
Rectangles: primary terms
Ovals: synonyms
Solid lines: “is a”
relationships (e.g. an apoptotic vesicle is a type of extracellular vesicle)
Dashed lines: synonym
relationships
Protein-lipid complex
HDL
L
DL
Lipoprotein
VLDL
Protein-lipid-RNA
complex