PPT-Mutations

Mutations Any unpredictable change in the structure or amount of DNA of an organism is called a mutation Most mutations occur in somatic body cells and are not passed from one generation to the next . Changes in . DNA. that affect genetic information. Gene Mutations. Point Mutations – changes . in one or a few. nucleotides. Substitution. THE FAT CAT ATE THE RAT. THE FAT HAT ATE THE RAT. Insertion. What Are Mutations?. Mutation: . Changes . in the nucleotide sequence of . DNA. Mutagen: . A physical or chemical agent that changes DNA. Mutation May . occur . in:. somatic cells (body cells): . will not be . Mutations are changes in the genetic material. . Mutations may be genetic mutations or chromosomal mutations.. Genetic Mutations occur in the “code” on DNA or mRNA. Mistakes in . copying the DNA :. P Ferguson, L . Quek. , M . Metzner. , I Ahmed, C Garnett, S Jeffries, K . Piechocki. , R Danby, M . Raghavan. , A . Peniket. , M Griffiths, A Bacon, J Ward, K Wheatley, P Vyas, C Craddock. Introduction. and Causes. What kinds of mutations can occur?. Mutations:. Mutations: are changes in the genetic material.. Mutations can produce changes in a single nucleotide to a whole chromosome. . Gene Mutations:. >2500 cancer genomes: Overall . functional . impact. Slides freely . downloadable . from . Lectures.GersteinLab.org. . & “tweetable” . (via . @. markgerstein. ). . See last slide . for more info.. What happens if there is a mistake (. mutation. ). in the DNA code?. Possibly proteins won’t be made or are made improperly.. If the mutations occur in the gametes, the offspring’s DNA will be affected positively, negatively, or neutrally.. http://io9.gizmodo.com/10-unusual-genetic-mutations-in-humans-470843733. Unharmful. Mutations. Mila . Kunis. has complete . heterochromia. . Kate Bosworth has . sectoral. . heterochromia. . Angelina Jolie has central . Dun . dun. dun!!!!! . Nobody’s perfect all the time . About 1/10 billion base pairs end up with a error or mutation . Mutation: . Mistake in replication or environmental effect that results in a c. Changes in the genetic material. Mutations can occur in two different types of Cells:. 1. Somatic (body) cells. 2. Gamete (sex or germ) cells. Mutations in somatic cells. Usually result in killing that body cell only.. M. istakes made in the DNA sequencing. They can have a range of effects.. They can affect the genetic information that is passed to offspring.. Cells have evolved various methods to deal with them. . Understand how they occur. Analyze the different types of mutations. Understand how mutations affect amino acid sequences and proteins. Objective. Central Dogma. DNA is transcribed into RNA, RNA is translated into proteins. Small-scale mutations. Missense mutations. Nonsense mutations. Silent mutations. Frameshift mutations. Large scale mutations. Causes. Mutagens. The results of mutation. Mutations. Genetic mutations are changes in the DNA sequence, caused by various mechanisms.. Science. Learning intention. To understand the different types of mutations. . You will need. A pen and a piece of paper or a laptop to record your answers. . You may need the internet to search for answers. .