KWWSVGRLRUJ1 3XEOLVKHGRQOLQHEDPEULGJH8QLYHUVLW3UHVV not be affected by nutrition but ID: 961544
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The protein requirement Indies, Jamaica K W W S V G R L R U J % - 1 3 X E O L V K H G R Q O L Q H E \ & D P E U L G J H 8 Q L Y H U V L W \ 3 U H V V not be affected by nutrition, but from previous experience can grow is much normal (Waterlow, depleted children might therefore requirement for normal growth, depleted child were made seventeen infants varying stages and one studies these children composition per skim milk protein/kg daily, produced rapid shown in later balance periods protein intake until N maintained. Each balance days on followed by urine and Body-weights were measured daily on a Growth study Twelve children who nearly regained, a diet kcal/kg and from h N balances were made carefully standardized, is a for measurement gain to some meaning. an unselected series malnourished infants treated in ward showed significant relationship between int
ake and protein intake (Waterlow, diet consisted dried skim cane sugar kcal/l. and in amounts designed g/l., and New Zealand, and had a net protein utilization (standardized), measured Queen Elizabeth Orange juice vitamins were given daily. Calorie were calculated by the standard kcal/g for carbohydrate and protein, kcal/g for fat. collection of intake and determination were those described in an earlier K W W S V G R L R U J % - 1 3 X E O L V K H G R Q O L Q H E \ & D P E U L G J H 8 Q L Y H U V L W \ 3 U H V V urine and stools were classical biological related to intake and not retained on retained on protein-free diet on test diet-tendogenous regression line (intercept on maintenance requirement line is maintenance require- ment has been estimated directly, whereas have calculated required for maintenance children, and their intakes and retentions, are s
hown for the and in Table growth study. plotted together that the curvilinear, as in theory 1946; Hegsted it seemed justifiable to treat two groups, draw two regression lines, corresponding arbitrarily, because regression line intakes were more retention in line cuts day, and therefore, is maintenance requirement. regression line From the given level malnourished children retain more no consistent relation between weight deficit are unable K W W S V G R L R U J % - 1 3 X E O L V K H G R Q O L Q H E \ & D P E U L G J H 8 Q L Y H U V L W \ 3 U H V V 778 - e - - 111111 80 100 140 160 180 200 220 240 260 280 100 I2O 1 - $ 80 60 c g 40 2 z M v ? .- * 3 20 - 20 t H. CHAN AND J. C. WATERLOW Nitrogen retention infants about year old mg/kg day. for height in order decreasing intake. repeated balances on same subject. At beginning equilibrium period. weights and hei
ghts taken as 50th percentile K W W S V G R L R U J % - 1 3 X E O L V K H G R Q O L Q H E \ & D P E U L G J H 8 Q L Y H U V L W \ 3 U H V V simply be small number subjects and significance can be body-weight shown last column values represent weight change observed over are required study together with preliminary feeding period. weight change, in infants restrained for are presented lower levels expected expected intake retained Weight retained Weight" weight for height for (mg/ height" ageX kg day) day) gain) 3.26 93'5 89 209 97'5 89.5 Calculated as as (required for maintenance taken as balances: comparison expected weight for height) day) no. children Mean Range Expected" Observed admission 44'5 38.5 intake-average obligatory not large, results in secure satisfactory weight gain. of gain in the six children with normal child K W W S V G R L R U
J % - 1 3 X E O L V K H G R Q O L Q H E \ & D P E U L G J H 8 Q L Y H U V L W \ 3 U H V V day, falling to about next 6 months average 2-91 weight gain were retained. that there any deposition high side, this rate metabolism, activity 90 kcal/kg day (Clements, 1949; this must be as the requirement for tissue (Waterlow, regression line corresponding to retention in day. According to this expected retention would virtually constant, error, at about that the group supports great majority individual variations fact that this group weight deficit to the intakes compared with those reported Wills, 1960), even fully recovered children retained large proportion explanation for high rates weight gain in the children in substantially regained their normal for height, were still normal height for their each child corresponded chronological age (average months, compared with nor
mal child 6 and 9 months should be gaining addition these children were showing some degree g/kg day do not retention reaches plateau, although reasonable grounds, is unusual. has often been observed, normal children, that the attributed this to the is taken day, and fall, from seems from day would be a suitable tests on young children different protein foods. levels have been used, which erroneous results. K W W S V G R L R U J % - 1 3 X E O L V K H G R Q O L Q H E \ & D P E U L G J H 8 Q L Y H U V L W \ 3 U H V V surprisingly high. child who when infants were to a protein intake N during adult (Chan, to be published). in infants protein with normal rate, should be adequate for normal growth, is possible even less result obtained direct observation with previous estimates for 1959, 1964) these calculations from an estimate ‘basal’ N on a term
45;endogenous’ longer suitable, since absolute distinction can made between endogenous exogenous metabolism. Obligatory’ is preferable. is meant before there has been significant body protein, i.e. measured after protein-free diet 1959, 1964) endogenous urinary derived from tabulated by Brody year old calculated with would be mg/kg day. this must be added basal faecal loss, Fomon, deMaeyer total by used by the WHO/FAO extrapolation from earlier balance studies were mostly not very satisfactory; direct measurements at a urine and results obtained by measurement, by extra- empirical formula general agreement found for younger infants older children and adults. estimating requirements, is safer the upper are added and stress, done in the WHO/FAO requirement at this must be added individual variations, giving a total reference protein protein/kg day. observations reported here does in fact satisfy child
6;s requirement. For the is in too high K W W S V G R L R U J % - 1 3 X E O L V K H G R Q O L Q H E \ & D P E U L G J H 8 Q L Y H U V L W \ 3 U H V V record our gratitude World Health Organization for grant in interest and encouragement. Acad. Sci. Bioenergetics and Reinhold Publishing Mammalian Protein Metabolism. Metabolism. N. Munro and J. B. Alli- Hegsted, D. M. & Chang, Y. 0. (1965). J. Nutr. 87, 19. Montgomery, R. D. (1962). J. clin. Inwest. 41, 1653. Nelson, W. E. (1954). Textbook of Puediatrics. Philadelphia and London: W. B. Saunders Co. WHO (1965). Tech. Rep. Ser. Wld Hlth Org. no. 301. Wallace, W. M. (1959). Fedn Proc. Fedn Am. Socs exp. Biol. son, editors.] Academic Press Great Britain K W W S V G R L R U J % - 1 3 X E O L V K H G R Q O L Q H E \ & D P E U L G J H 8 Q L Y H U V L W \ 3 U H