Professor Clare Heal and Dr Daniel Charles The Research Question Is the use of alcoholic chlorhexidine for skin antisepsis superior to aqueous chlorhexidine in preventing SSI after minor skin excisions in general ID: 914624
Download Presentation The PPT/PDF document "Aqueous v Alcoholic Chlorhexidine for sk..." is the property of its rightful owner. Permission is granted to download and print the materials on this web site for personal, non-commercial use only, and to display it on your personal computer provided you do not modify the materials and that you retain all copyright notices contained in the materials. By downloading content from our website, you accept the terms of this agreement.
Slide1
Aqueous v Alcoholic Chlorhexidine for skin antisepsis
Professor Clare Heal and Dr Daniel Charles
Slide2The Research Question
Is the use of alcoholic chlorhexidine for skin antisepsis superior to
aqueous chlorhexidine in preventing SSI after minor skin excisions in general practice?
Slide3Research Design and Method
4 general practices in North Queensland, Australia
Prospective multicentre randomised controlled trial Consecutive patients ‘minor skin excisions’ Intervention: 0.5% CHG in 70% alcohol Control: 0.5% CHG aqueous solution
Slide4What the Research Found
Overall incidence infection 6.3% (57/909) 5.8% (26/451)(95%CI 3.4-7.6) alcoholic6.8%
(31/458) (95%CI 4.2-9.1) aqueousNo significant difference in SSI p= 0.652Absolute risk difference -0.9% [-0.021 to +0.039] NNT 112
Slide5What this means for Clinical Practice
GPs can safely use aqueous chlorhexidine for skin antisepsisAqueous has some advantages over alcoholic chlorhexidine
Lower risk of:Mucosal irritationDissolving surgical pen markingsOperating room fires!