PPT-1 How does insulin work? (~1984)

Pierre De Meyts Chuck head of research at Novo Nordsk Aug Insulin Insulin Receptor Activates a series of downstream signaling cascades leading to pleiotropic effects on How does insulin . Prof. dr. . Zoran. . Vali. ć. Department of Physiology. University of Split School of Medicine. digestive functions. two important hormones: insulin and glucagon . (. crucial for normal regulation of glucose, lipid, and protein metabolism. the Treatment of T1DM and T2DM. Lawrence Blonde, MD, FACP, FACE. Director of the . Ochsner. Diabetes Clinical Research Unit. Ochsner. Medical Center. New Orleans, Louisiana. Vivian . A. Fonseca, MD, FRCP. ST. TIME. IN A GOVERNMENT HOSPITAL . “ JJ HOSPITAL, MUMBAI ” . Dr . . Hemant. Gupta . [Associate . Prof. & Unit Head, Dept of Medicine, . J.J.Hospital. , . Mumbai] . Dr . . Ayaz. Ahmed [lecturer]. Trial. Treatment Protocols. Askiel Bruno, MD, MS. Protocol PI. Agenda. General protocol for control group/ intervention group. Discussion of meals. H. ypoglycemia protocol. Pauses of study protocol. Pharmacoepidemiology and Drug Safety. 2008;(17):753-759.. So benefit of both SU/Insulin in. research studies –UKPDS, DCCT/EDIC. But adverse risk in ‘real world’ use. Link between hypoglycemia and acute cardiovascular events in type 2 diabetes. *. Stephen W. Ponder MD, FAAP, CDE. Scott & White Clinic. Temple, Round Rock and College Station. *. . And a bunch of other important stuff. One goal of diabetes care is managing glucose…. FLUX. Radioimmunoassay. Radioimmunoassay (RIA) is a very sensitive in vitro assay technique used to measure concentrations of antigens (for example, hormone levels in the blood) by use of antibodies.. RIA technique is extremely sensitive and extremely specific, requiring specialized . Primer on Regulation of Body Fat. Biological factors regulate amount of fat in our bodies. Modified by genetics. Diets can affect this process. Carbohydrate Metabolism. As . carbs. are digested, they are sent to bloodstream as glucose. R. esistance and Diabetes. Alfred Martello, MD. Medical Director. The Ohio Anesthesia Group. Disclosures. No Commercial endorsements. I’m not really smart enough to give this lecture.. It’s really complicated stuff.. . David Beran. Researcher and Lecturer. University of Geneva. Multi-level assessment of Health system. Macro. Ministry of Health . Ministry of Trade. Ministry of Finance. Central Medical Store. National Diabetes Association. . David Beran. Researcher and Lecturer. University of Geneva. Multi-level assessment of Health system. Macro. Ministry of Health . Ministry of Trade. Ministry of Finance. Central Medical Store. National Diabetes Association. Born Eric Arthur Blair of a British colonial civil servant in India. Went to school in England. Once out of school he joined the Indian Imperial Police in Burma. He resigned from the police force in 1927 to become a writer. Dr . Waqar. Malik. Consultant . Diabetologist. Blakesley. Hall, . Blakesley. Road, Birmingham. 9. th. Jan. 2017. Lay Out. Why glycaemic control is important and what role insulin plays. Different insulins old and new. Beta Cells in the Pancreas. Insulin is synthesized in beta cells. Insulin helps to regulate metabolism of carbohydrates and fats. Insulin is secreted by the pancreas. Without insulin to facilitate absorption of glucose the levels become too high.