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r the EA P C Country of the Month initiative September 2020 Curriculum Vitae Shinji KOBA MDPhD Professor Cardiologist Director of the J apanese A ssociation of C ardiac R ehabilit ID: 849407

university medicine showa school medicine university school showa koba department cardiology tokyo division 2018 japan professor 2020 thromb atheroscler

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1 Prepared fo r the EA P C “Country o
Prepared fo r the EA P C “Country of the Month” initiative , September 2020 Curriculum Vitae Shinji KOBA MD,PhD, Professor, Cardiologist , Director of the J apanese A ssociation of C ardiac R ehabilitation (JACR) Department of Medicine, Division of Cardiology, Showa University School of Medicine , Japan Shinji Koba Director of JACR _____________________________________________________ ______________________ Short CV Current activities • Teaching and administrative duties, Showa University School of Medicine and Showa University Hospital • Vice President of Japanese Association of Cardiac Rehabilitation (2018 - 2020) Degree of Qualification 1988 M.D. Showa University School of Medicine 1994 Ph.D. Showa University Postgraduate School of Medicine, Tokyo, Awarded the degree of Doctor of Medical Science (Ph.D.) Res earch and Academic Appointments • September 1995 - September 1997 Postdoctoral Research Fellow, Division of Cardiology, Department of Internal Medicine, The University of Texas - Houston Medical School, TX, USA • June 2003 - April 2008: Assistant Professor, Third Department of Internal Medicine, Showa University School of Medicine, Tokyo, Japan • April 2008 - February 2014: Assistant Professor, Department of Medicine, Division of Cardiology, Showa University School of Medicine, Tokyo, Japan • March 2014 - July 2018: Associate Professor, Department of Medicine, Division of Cardiology, Showa University School of Medicine, Tokyo, Japan • Augus t 2018 - present: Professor, Department of Medicine, Division of Cardiology, Showa University School of Medicine, Tokyo, Japan • April 2020 - present: Professor, Department of Perioperative Medicine, Division of Comprehensive Internal Medicine, Showa University School of Dentistry, Tokyo, Japan Research Area Cardiac rehabilitation, Atherosclerosis, General cardiology, Preventive cardiology (rehabilitation, exercise, lifestyle modification and nutrition), Dyslipidemia, Ischemic heart disease Prepared fo r the EA P C “Country of the Month” initiative , September 2020 Current Publications 1.

2 Kayano H, Koba S, Hirano T, Matsui T,
Kayano H, Koba S, Hirano T, Matsui T, Fukuoka H, Tsuijita H, Tsukamoto S, Hayashi T, Toshida T, Watanabe N, Hamazaki Y, Geshi E, Murakami M, Aihara K, Kaneko K, Yamada H, Kobayashi Y, Shinke T : Dapagliflozin Influences Ventricular Hemodynamics and Exercis e - Induced Pulmonary Hypertension in Type 2 Diabetes: Randomized Controlled Trial. Circ J. 2020 ;84(10):1807 - 1817 . doi: 10.1253/circj.CJ - 20 - 0341 . PMID: 32921680 . 2. Koba S, Inoue I, Cyrille M, Lu C, Inomata H, Shimauchi J, Kajinami K: Evolocumab vs . ezetimibe in statin - intolerant hyperlipidemic Japanese patients: Phase 3 GAUSS - 4 trial. J Atheroscler Thromb 2020;27:471 - 484. 3. Koba S, Takao T, Shimizu F, Ogawa M, Ishii Y, Yokota Y, Furuyama F, Tsunoda F, Shoji M, Harris WS, Takada A: Comparison of Plasma Levels of Different Species of Trans Fatty Acids in Japanese Male Patients with Acute Coronary Syndrome Versus Healthy Men. Atherosclerosis 2019;284:173 - 180. doi: 10.1016/j.atherosclerosis.2019.02.025. 4. Sakai K, Koba S, Nakamura Y, Yokota Y, Tsunoda F, Shoji M, Itoh Y, Hamazaki Y, Kobayashi Y: Small Dense LDL Cholesterol is a Promising Biomarker for Secondary Prevention in Elder Men with Stable Coronary Artery Disease. Geriatr Gerontol Int 2018;18:965 - 9 72. 5. Furuyama F, Koba S, Yokota Y, Tsunoda F, Shoji M, Kobayashi Y: Effects of Cardiac Rehabilitation on High - Density Lipoprotein - mediated Cholesterol Efflux Capacity and Paraoxonase - 1 activity in Patients with Acute Coronary Syndrome. J Atheroscler Thromb 2018;25(2):153 - 169. 6. Koba S: Physical Fitness and Development of High non - High - Density Lipoprotein Cholesterol. J Atheroscler Thromb 2018; 25(12):1185 - 1187. doi: 10.5551/jat.ED105 7. Koba S, Ayaori M, Uto - Kondo H, Furuyama1 F, Yokota Y, Tsunoda F, Shoji M, I kewaki K, Kobayashi Y: Beneficial effects of exercise - based cardiac rehabilitation on high - density lipoprotein - mediated cholesterol efflux capacity in patients with acute coronary syndrome. J Atheroscler Thromb 2016;23(7):865 - 877. 8. Koba S: Physical activity and chronic kidney disease. J Atheroscler Thromb 2016;23(4):395 - 396. doi: 10.5551/jat.ED039. PMID: 3036954