By MURSHIDA BT SHAHUL HAMEED D11A019 NURUL SYUHADAH BT RIBUAN D11A032 NUR NABILA BT MOHD ROZAINI D11A027 ID: 913191
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URINARY BLADDER & BULBOURETHRAL GLAND
By:MURSHIDA BT SHAHUL HAMEED D11A019NURUL SYUHADAH BT RIBUAN D11A032NUR NABILA BT MOHD ROZAINI D11A027FATHIYAH BT MUHAMAD JUFRI D11A006AZREENASHAFIQAH BT AZMEE D11A005
Slide2URINARY BLADDER- ANATOMICAL ASPECT
BY : MURSHIDA BT SHAHUL HAMEED
Slide3Is a hollow musculomembraneous
organ that varies in form,size and position depending on the amount of urine it contains.Small and globular,when contracted and lies on the pubic bone.Carnivores-It extend into the abdomenLarger animals-it is confined to the pelvic cavity.During filling,it enlarges gradually and become pear-shaped.
Slide4Slide5The bladder can be divided into cranial vertex , Intermediate body and caudal neck which is continuous with the urethra.
The bladder is supported by double layers of peritoneum.Most of the surface of the bladder,except the caudal part of the neck of the bladder is covered with peritoneum,which continuous as the ligaments of the bladder onto the body walls.
Slide6Slide7HISTOLOGY OF URINARY BLADDER
BY: NURUL SYUHADAH BT RIBUANThe bladder has same tissue layers as renal pelvis and ureter. The layers are:
-Mucosa: Transitional epithelium
-
Submucosa
: Lamina
Propria
-
Muscularis
: Layers of smooth muscle
-
Serosa
: Visceral peritoneum
Slide8Histology of mucosa
The inner portion of urinary bladderTransitional epithelium will change shape from cuboidal cells to squamous cells as the bladder expands.The epithelial layer not contain blood vessels or lymphatics. The basement is a single layer cells.The basement membrane separate epithelium from connective tissue.
Basal layer of epithelium
Superficial layer of epithelium
Slide9Histology of submucosa
The epithelium lies after connective tissue called lamina propria.It composed of areolar connective tissue (Soft tissue found in many areas including surrounding the blood vessels and nerves and forming the layer that flexibly attaches the skin to the muscles).It also contains blood vessels,nerves and sometimes glands.
Lamina propria
of the mucosa
Slide10Histology of muscularis
Underneath of submucosa of bladder is a layer called muscularis.It consists of 3 layer of smooth muscles: inner longitudinal,middle circular and outer longitudinal.Contraction of these muscles expels the urine from the bladder.
Slide11Histology of serosa
Serosa is covering the upper region of the bladder.Serosa composed of simple squamous epithelium overlying a small bit of connective tissue.The outer layer of bladder is adventitia which composed of connective tissue.The serosa is visceral peritoneum.Beyond of the serosa covering of bladder is perivesical fat.This is a layer of fat surrounding bladder.
Slide12Bulbourethral Gland(anatomical aspect)
BY: NUR NABILA BT MOHD ROZAINI
Slide13Also known as Cowper’s glands.One of the accessory gland for male reproductive system.Paired glands located on either side of the urethra.Tubular or tubuloalveolar
gland.Surrounded by striated muscle.Horse’s Bulbourethral glands, dorsal view
Slide14The glands have ducts that empty into the urethra, the tube through which both urine and semen pass.Composed of several lobules held together by a fibrous covering. Lined
by columnar epithelial cells, opening into a duct that joins with the ducts of other lobules to form a single excretory duct.This ducts opens into the urethra at the base of the penis.
Slide15Slide16HISTOLOGY OF BULBOURETHRAL GLAND
BY: FATHIYAH JUFRI
Slide17All domestic animals have bulbourethral glands except dogThe glands are compound tubuloalveolar glands ,structurally resemble mucus secretory glandsSimple columnar epithelium ,which varies in height depend on functional state of
gland,is under control of testosteroneSmaller excretory ducts from secretory units lined with secretory cells while larger excretory ducts exhibit pseudostratified or stratified columnar epithelium
Slide18The glands exhibit either acinar secretory units or
tubular secretory unitsThe secretory cells are cuboidal,low columnar or squamous ,and light stainingFibroelastic capsule surrounds these glands contain connective tissue,smooth muscle fibers and skeletal muscle fibers in the interlobular connective tissue septumConnective tissue septa from capsule divide the gland into several lobules
TUBULAR SECRETORY UNITS
EXCRETORY DUCT
SKELETAL MUSCLE FIBERS(L)
SKELETAL MUSCLE FIBERS(T)
CONNECTIVE TISSUE CAPSULE
ACINAR TUBULAR UNITS
CONNECTIVE TISSUE SEPTUM
Slide19Mouse Bulbourethral GlandsBulbourethral glands are androgen-regulated accessory glands that are analogous to Cowper’s glands in humansThe bulbourethral glands in mice are
multilobular.Each lobule composed of acini that opens into centrally located canal.Thin capsule of fibrous connective tissue surrounds and separates the acini.The acini composed of epithelial cells.
Slide20In secretory state-epithelium has abundant ,foamy cytoplasmIn resting state—the cytoplasm is
eosinophilic(appearance of cell) and finey granular.Secretory cells are found mainly in body and resting cells are found in tail.The ductular epithelium is cuboidal.Older mice may develop cystic bulbourethral glands.
Slide21ACINI TUBULAR GLAND lined by tall columnar epithelium
SKELETAL MUSLE
Slide22Histology of male genital organ in mouse
BULBOCAVERNOSUS MUSCLE
Slide23FUNCTION OF URINARY BLADDER & BULBOURETHRAL GLAND
BY: AZREENASHAFIQAH BT AZMEE
Slide24URINARY BLADDER
An organ that collects urine excreted by the kidneys before disposal by urination. -Urine enters the bladder via the ureter and exits via the urethra.
Slide25BULBOURETHRAL GLAND
Male sexual glands. Located below the prostate and discharge a component of the seminal fluid into the urethra.Secretions provide fluid to lubricate and clean the lower urethra, which may have residue left from its use during urination.
Slide26During sexual arousal each gland produces a clear, salty, viscous secretion known as pre-ejaculate. This fluid helps to lubricate the urethra for spermatozoa to pass through, neutralizing traces of acidic urine in the urethra, and helps flush out any residual urine or foreign matter.
It is possible for this fluid to pick up sperm, remaining in the urethral bulb from previous ejaculations, and carry them out prior to the next ejaculation. It also produces some amount of prostate-specific antigen (PSA), and Cowper's tumors may increase PSA to a level that makes prostate cancer suspected.