2 Gregor Mendel 1865 Frederick Miescher Embryologist He collected bandages from nearby clinic And wash off the pus Isolated a new molecule NUCLEIN from the cells nucleus in 1869 ID: 933307
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Slide1
The History
of
DNA
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2
Gregor
Mendel
1865
Slide3Frederick
Miescher
Embryologist
He collected bandages from nearby clinic
And wash off the pus.
Isolated a new molecule
NUCLEIN from the cells nucleus in 1869.
H,N, P, and O
1871 He publish his findings.
Proteins were the molecule of heredityDie of tuberculosis in 1895.
1844- 1895
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FREDRICK GRIFFITH
http://timerime.com/en/event/674690/Frederick+Griffith/
1928
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http://www.nature.com/scitable/topicpage/isolating-hereditary-material-frederick-griffith-oswald-avery-336
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OSWALD AVERY
COLIN MACLEOD
MACLYN
McCARTY
http://profiles.nlm.nih.gov/CC/Views/Exhibit/visuals/after.html
Avery Experiment
1944
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LINUS PAULING
1948
http://osulibrary.oregonstate.edu/specialcollections/coll/pauling/dna/narrative/page1.html
He proposed that the DNA structure was a triple helix, though he was later disproven.
The fact that he determined DNA to be
three dimensional
is still a much celebrated accomplishment
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ERWIN CHARGAFF
1950
Chargaff's observation that in the base composition of DNA the quantity of adenine equaled the quantity of thymine and the quantity of guanine equaled the quantity of cytosine
A = T
C = G
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Organisms
A
T
G
C
Homo sapiens
31
31.5
19.1
18.4
Drosophila
melanogaster
27.3
27.6
22.5
22.5
Zea
mays
25.6
25.3
24.5
24.6
Neurospora
crassa
23
23.3
27.1
26.6
Escherichia coli
24.6
24.3
25.5
25.6
Bacillus
subtilis
28.4
29
21
21.6
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MAURICE WILKINS
ROSALIND FRANKLIN
1951
http://gandt.blogs.brynmawr.edu/web-papers/web-papers-2/women-in-science/
Slide11Rosalind Franklin
English Biologist
Made and X-ray of DNA.
She was an instrument in discovering the
structure of DNA.
Also Known as the Dark Lady of the DNA
X-ray diffraction specialist.
X-Ray 51
Die in 1958 at age of 37 of ovarian cancer.
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http://osulibrary.oregonstate.edu/specialcollections/coll/pauling/dna/narrative/page1.html
X-Ray 51
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MARTHA CHASE
ALFRED HERSHEY
http://osulibrary.oregonstate.edu/specialcollections/coll/pauling/dna/narrative/page1.html
1952
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FRANCIS CRICK AND JAMES WATSON
1953
http://osulibrary.oregonstate.edu/specialcollections/coll/pauling/dna/narrative/page1.html
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http://osulibrary.oregonstate.edu/specialcollections/coll/pauling/dna/narrative/page1.html
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http://osulibrary.oregonstate.edu/specialcollections/coll/pauling/dna/narrative/page1.html
Noble Price 1962
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http://commons.wikimedia.org/wiki/File:DNA-structure-and-bases.png
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http://commons.wikimedia.org/wiki/File:Nucleotides_1.svg
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