PPT-Biology UNIT Genetic Inheritance

October 19 th October 30 th March 27 th March 31st Female Karyotype Karyotype the complete set of chromosome in the cells of an organism Homologous chromosomes there are two copies of each chromosome same size same shape same genes. INTRODUCTION TO GENETICS. APPLIED GENETICS. Chapter 14A: INTRODUCTION TO GENETICS. Mendel. Rules and Terminology for Examination of Genetic Inheritance. Expanding the Rules and Terminology to follow two (or more) genes in a cross. 5.3- . Following. Patterns . of . Inheritance. in . Humans. What is a Pedigree?. Flowchart; “Genetic Family Tree. Symbols show inheritance patterns of traits over generations. Used to determine presence/absence of an allele responsible for disease in an individual.. first and second lectures . Introduction and brief history . B y Dr. . Sawsan. . Sajid. Al-. Jubori. . References . :. 1-. Essential . of molecular biology by George M. . Malacinski. 4. th. . Arend Sidow, Ph.D.. Professor, Departments of Pathology and Genetics, Stanford. An introduction that includes the most important concepts in Genetics and Genome Biology. 1. Genotype. Phenotype. Genetic Testing. Polydactyly. Down Syndrome. Hemophelia. Progeria. Hypertrichosis. Sickle Cell Anaemia. INTRODUCTION. What is genetic diseases/disorders?. The human body is composed up of cells , each one specializing a particular function like sensing light, smelling . Definition . Allelle. is . an alternative form of a . gene . (one member of a pair) that is located at a specific position on a specific . chromosome. . These DNA coding . determine distinct traits that can be passed on from parents to offspring. . Introduction and brief history . B y Dr. . Sawsan. . Sajid. Al-. Jubori. . References :. 1-Essential of molecular biology by George M. . Malacinski. 4. th. edition. 2-. Second references: Molecular biology (principles and practice). Inheriting Genetic Conditions Reprinted from https://ghr.nlm.nih.gov/ Lister Hill National Center for Biomedical Communications U.S. National Library of Medicine National Institutes of Health Departm Tel. No. 2419677/2419361 e - - mysore.ac.in Fax: 0821 - 2419363/2419301 www.uni - mysore.ac.in UNIVERSITY OF MYSORE Estd. 1916 Vishwavidyanilaya Karyasoudha Crawford Hall, Mysuru - 570 005 N ;. . the. . study of . biology. at the . molecular. level.. Molecular biology. ;. . the. . study of . gene . structure and functions at the . molecular level. . to understand the molecular basis of hereditary, genetic variation, and the expression patterns of genes. . and brief history . References :. 1-Essential of molecular biology by George M. . Malacinski. 4. th. edition. 2-Second references: Molecular biology (principles and practice). . first . lecture . A2 BIOLOGY UNIT 3. Maximum mark = 90. Mean mark = 37.6. Entry = 2150. A*. A. B. C. D. E. Grade boundary. 54. 46. 40. 34. 29. 24. Cumulative % at grade. 11.7. 27.9. 43.8. 60.7. 75.8. 87.3. Item level data. Complex Patterns of Inheritance. Incomplete dominance (review). Co-Dominance (review). Multiple alleles – pattern of inheritance is determined by two or more alleles. . Blood types (next slide) – three forms (I. TERMINOLOGY OF GENETIC AND CONGENITAL DISORDERS. Congenital. Allele. Gene locus. Gene mutation. Genotype. Phenotype. Homozygous. Heterozygous. Polymorphism. Gene penetrance. Gene expression. CAUSES OF BIRTH DEFECTS.