PDF-(BOOS)-Manual for the Laboratory Diagnosis and Virological Surveillance of Influenza

In many settings influenza is recognized as a major cause of disease and death In other parts of the world however its epidemiology and the degree of its impact on human health remain relatively uncertain in large part due to a lack of virological and disease surveillanceWHO has developed this manual to strengthen the laboratory diagnosis and virological surveillance of influenza infection by providing standard methods for the collection detection isolation and characterization of viruses The specific objectives of the manual include increasing understanding of the principles and importance of haemagglutination and haemagglutination inhibition HAI testing in the identification of influenza virus field isolates and in serological diagnosis using the WHO Influenza Reagent Kit ensuring HAI test results are analyzed and interpreted accurately by including the appropriate controls and recognizing potential problems in interpreting test results increasing understanding of the principles of reverse transcription polymerase chain reaction RTPCR and its application in the typing and subtyping of influenza viruses highlighting the significance of influenza virus isolation as compared with direct antigen detection increasing understanding of the principles of the microneutralization assay and its application to serological diagnosis increasing understanding of the principles of the neuraminidase inhibition NAI assays used in the detection of virus strains resistant to antiviralsAll national and international influenza surveillance systems including those for monitoring clinical disease depend fundamentally upon the consistent and successful implementation. 2009 - 2010. Armed Forces Health Surveillance Center (AFHSC). United States Air Force School of Aerospace Medicine (USAFSAM). Naval Health Research Center (NHRC). DoD Global Influenza Network Partners (GEIS Operations). FluWatch. Influenza-like Illness (ILI) . surveillance system - Challenges and Opportunities. Dr. Christina . Bancej. , . Public Health Agency of Canada. on behalf of the 2015-16 . FluWatch. Team: Liza Lee, Joy . Accelerating progress towards measles and rubella elimination. Geneva, Switzerland 21-23 June 2016 . Jenny Rota, WHO consultant. Goal is to update information to reflect current responsibilities of the network, provide best practices, resources and guidelines. Respiratory Viruses Update. 2013-2014. Pete Shult, PhD.. Director, Communicable Disease Division . and Emergency Response. Erik Reisdorf, MPH M (ASCP). CM. Team . Lead, . Virology Laboratory. WCLN . 19. th. – 21. st. October 2017. Tsirang. Background. Influenza Like-illness surveillance was established in 2009 as preparedness against H1N1 pandemic.. Burden of influenza. Dominant circulating strains. th. January 2016, . Paro. Training Objective. General Objective. To strengthen Influenza sentinel surveillance system. Specific Objectives. To update the participants on global, regional and local influenza surveillance status. www.cdc.gov/COVID19 COVID - 19 Surveillance Webinar Sentinel Surveillance Laboratory Testing and WHO Global Influenza Surveillance and Response System Reporting Meg McCarron, Influenza Division Olg 1 CONTENTS _______________________________________________________________3 1. Overview___________________________________________________________5 1.1. Background__________________________________ an increase in the number of cases of a disease above what is normally expected . science of protecting and improving the health of people and their communities. a preparation that provides a trigger to help the immune system build immunity. Cedric Lazarus. Livestock Development Officer. FAO Sub-regional Offices for . Central America and the Caribbean. 1. Food and Agriculture Organization. Technical . Cooperation . Programme. in the . Americas. Thoroughly updated for its Sixth Edition, this manual is a highly practical guide to the diagnosis and management of eye disorders and injuries. Experts from Harvard Medical School and the Massachusetts Eye and Ear Infirmary present authoritative, state-of-the-art recommendations in a rapid-access outline format. Appendices include up-to-date ophthalmic drug and systemic antimicrobial formularies with dosages.All chapters have been updated to include the latest information on new disease entities, diagnostic techniques, drugs, and treatments, including LASIK and LASEK surgery, cataract extractions, intraocular lenses, use of botulinum for blepharospasm, and medical treatment of glaucoma. Thirty new full-color images have been added. In many settings influenza is recognized as a major cause of disease and death. In other parts of the world however, its epidemiology and the degree of its impact on human health remain relatively uncertain -- in large part due to a lack of virological and disease surveillance.WHO has developed this manual to strengthen the laboratory diagnosis and virological surveillance of influenza infection by providing standard methods for the collection, detection, isolation and characterization of viruses. The specific objectives of the manual include: * increasing understanding of the principles and importance of haemagglutination and haemagglutination inhibition (HAI) testing in the identification of influenza virus field isolates, and in serological diagnosis using the WHO Influenza Reagent Kit* ensuring HAI test results are analyzed and interpreted accurately by including the appropriate controls and recognizing potential problems in interpreting test results* increasing understanding of the principles of reverse transcription polymerase chain reaction (RT-PCR) and its application in the typing and subtyping of influenza viruses* highlighting the significance of influenza virus isolation as compared with direct antigen detection* increasing understanding of the principles of the microneutralization assay and its application to serological diagnosis* increasing understanding of the principles of the neuraminidase inhibition (NAI) assays used in the detection of virus strains resistant to antivirals.All national and international influenza surveillance systems -- including those for monitoring clinical disease -- depend fundamentally upon the consistent and successful implementation. State of Alaska Division of Public Health, Section of Laboratories. Alaska State Virology Laboratory – Fairbanks. Anchorage State Public Health Laboratory – Anchorage. Jayme Parker, HCLD(ABB), PhD, MSPH, MB(ASCP). Emilio Gonzales. Overview. Considerations for Influenza (Flu) Surveillance. Goals for the Upcoming Season and Year. Projected Timeframes. Considerations:. Respiratory Disease Surveillance. Structure of influenza surveillance reporter network.