PPT-CHAPTER 16 THE MOLECULAR BASIS OF INHERITANCE

1 OVERVIEW 2 By the 1940s scientists knew that chromosomes carried hereditary material and consisted of DNA and protein Most thought that protein was the genetic material because proteins were macromolecules. Jr. Discovery of Cyclic AMP. Ferid. . Murad. Nitric Oxide Signaling. Alfred G. Gilman. G-protein Signal Transduction. Heritage of the CWRU Department of Pharmacology. Nobel Prize. Kris Palczewski, Chairman of Pharmacology. Chapter 16: DNA structure and replication. You must know. The structure of DNA. The knowledge about DNA gained from the work of Griffith; Avery, MacLeod, and McCarty; Hershey and Chase; Wilkins and Franklin; and Watson and Crick. Chapter 16. Chromosomes. Chromosome. Supercoils. Coils. Nucleosome. Histones. DNA. double. helix. Evidence That DNA Can Transform Bacteria. Frederick Griffith’s experiment 1928. Griffith called the phenomenon . The chromosomal basis of sex varies with the organism. Sex-linked genes have unique patterns of inheritance. Copyright © 2002 Pearson Education, Inc., publishing as Benjamin Cummings. Genetics. 3. In human and other mammals, there are two varieties of sex chromosomes, . 1. Inheritance. Inheritance. allows a software developer to derive a new class from an existing one. The existing class is called the . parent class,. or . superclass. , or . base class. The derived class is called the . The chromosomal basis of sex varies with the organism. Sex-linked genes have unique patterns of inheritance. Copyright © 2002 Pearson Education, Inc., publishing as Benjamin Cummings. Genetics. 3. In human and other mammals, there are two varieties of sex chromosomes, . Overview of Genetics. Genetics – Overview. Genetics is the study of heredity and variation . Genetics is the unifying discipline in biology. Explains why organisms have certain traits . How traits are passed from parent to offspring.  . Studying genetics . can be accomplished in part by . investigating the history of discoveries. that have lead to our . understanding of DNA and its role in gene expression and biological inheritance. Physics 5403: Computational Physics. Physics. 5403: . Computational. . Physics. - . Chapter. 6: . Molecular. Dynamics. 1. 6.0 Overview. What is molecular dynamics (MD)?. Numerical method for studying many-particle systems such as molecules, clusters, and even macroscopic systems such as gases, liquids and solids . 1. Griffith . - . Transformation . Since Morgan showed that genes are found on chromosomes, . the new issue was whether the genetic material was in the proteins of the chromosomes or the DNA. . Most thought the . 1. Chromosomal Theory of Inheritance. Theodor . Boveri. Walter Sutton. In 1902, Walter Sutton and Theodor . Boveri. developed the . Chromosome Theory of Inheritance. . . This theory basically states that Mendelian genes have a specific locus on the chromosome and that chromosomes undergo segregation and independent assortment during meiosis. . 12.1 Chromosomal Inheritance . 1. Genes are located on chromosomes; this is called the . chromosome theory of inheritance. .. 12.1 Chromosomal Inheritance. Chromosomes can be categorized as two types:. 1. A. Background. . 1. Genetics. . 1860’s—. Mendel. . proposed that discrete . inherited . factors . segregate . and assort . independently . during gamete . formation. . 2. Cytology. . 2022-23 2022-23 2022-23 2022-23 2022-23 2022-23 2022-23 2022-23 2022-23 2022-23 2022-23 2022-23 2022-23 2022-23 2022-23 2022-23 2022-23 2022-23 2022-23 2022-23 2022-23 2022-23 2022-23 2022-23 2022-23