PPT-MOSH Toxicology Considerations

Hepatic Granulomas Marusia Popovech PhD MPH Senior Toxicologist ExxonMobil Biomedical Sciences Inc Member CONCAWE STF33 October 18 2017 Introduction F344 Hepatic Granuloma StrainDependent Differences . Toxicology. —measure of how armful a substance is. Potential . harm is dependent on. Dosage. Bioaccumulation. —some . molecules are absorbed & stored in specific . organs or . tissues at levels higher than normally would be expected. Topics for Principles of Toxicology: Part B. Endocrine Toxicity. Carcinogenicity. Neurotoxicity. Persistence and Bioaccumulation. The topics for “Part C” (what we could not cover). Summary. The systemic problem. Tiffany Bredfeldt, Ph.D. . Toxicology Division. Texas Commission on Environmental Quality. Advanced Air Permitting Seminar 2015. Updates. New Odor White Paper. Updated Odor Values. Reminder to Use New ESL Forms. Tracie Phillips, Ph.D. & Roberta Grant, Ph.D.. Toxicology Division. Texas Commission on Environmental Quality. Environmental Trade Fair 2015. Objectives. New Toxicology Database:. Database Introduction. IM4Q Annual Statewide Conference 2016. Guy . Caruso - Institute on . Disabilitie. s. . Nancy . Cohlhepp. . & Kathy . Glosser - Clarion Vocational . Services;. Jennifer . Harniman-Crangle - Chester County Department of . Toxicology. . Toxicology. —. the study of the adverse effects of chemicals or physical agents on living organisms. . (In other words: combination of chemistry and physiology that deals with drugs, poisons, and other toxic substances and how these substances effect living organisms.) . Copyright © Texas Education Agency, 2014. All rights reserved.. Copyright © Texas Education Agency, . 2014. . These Materials are copyrighted © and trademarked ™ as the property of the Texas Education Agency (TEA) and may not be reproduced without the express written permission of TEA, except under the following conditions:. Eun . Y. oung Jeong. Rebecca Sammy. Selvie Jegarajaratnam . Zakiya Mittal. Presentation Date: October 10, 2017. PHM142H1. PHM142 Fall . 2017. Instructor: Dr. Jeffrey Henderson. Introduction. Metalloid - both metal and nonmetal properties. Mahmoud . Hailat, PE. . INDOT-Bridge . Division. May 1, 2014. Integral Abutments – Outline. History & Updates . Advantages and Disadvantages . Types. Research Update – Purdue University . Design Criteria/ Considerations . IM4Q Annual Statewide Conference 2016. Guy . Caruso - Institute on . Disabilitie. s. . Nancy . Cohlhepp. . & Kathy . Glosser - Clarion Vocational . Services;. Jennifer . Harniman-Crangle - Chester County Department of . Anne E. Loccisano, PhD, DABT. Exponent, . Inc. VP-Elect, SOT/RSESS. GSLC-RSESS Webinar. October 31, 2017. What do regulatory toxicologists do anyway?. Broadly, regulatory toxicologists and risk assessors provide science-based advice to. Harmful Effects of Toxicology. It may damage the survival or normal functions of an individual.. What is Toxicity?. The degree to which a substance is poisonous or can cause injury.. The toxicity depends on a variety of factors.. Dan Villeneuve. US Environmental Protection Agency, Office of Research and Development. Center for Computational Toxicology and Exposure. Great Lakes Toxicology and Ecology Division*. *The contents of this presentation neither represent nor necessarily reflect official US EPA policy.. Decide. . whether. . you. . would. . agree. . with. . banning. . mosh. . pits. . or. not. . Then. . write. 2 . paragraphs. . selecting. . the. data/. evidence. . provided. in . the. .