PPT-Identification of Candidate CK2 Substrates in Mitosis by Quantitative Phosphoproteomics

Scott Rusin Kettenbach Lab NERIC 2017 August 18 th 2017 P ¾ of human proteins are phosphorylated Sharma et al 2014 P 500 human protein kinases ¾ of human proteins are phosphorylated. IB Biology. Cell Cycle. Mitosis. Prophase . Metaphase. Anaphase. Telophase. Lung Cancer. Meiosis. Mitosis vs. Meiosis. Crossover . Karyotype. Trisomy. Monosomy. Unit 5. Welcome Back! . Musical Chairs. TODAY:. Notes on Cell Cycle. Become medical school students on oncology . rotation. Homework for next time: Watch Bozeman video on cell cycle, mitosis and meiosis. There *may* be a quiz.. Notebook Page 12. Warm . Up & Spiral. 2/23/2017. What is the chemical formula for glucose? . How many hydrogen atoms are in glucose? . What is protein synthesis? . OBJECTIVES: 8.L.5.1. -TSWU that cells carry on the many functions needed to support life including cell respiration, photosynthesis, protein synthesis, mitosis, and meiosis. . When Making New Cells . Goes Terribly . Wrong. Regulating the cell cycle. Not all cells move through the cell cycle . at the same rate. :. Most Muscle cells and nerve cells do not divide at all once they have developed. Edited By: Ashlee Palermo. Objectives. Define mitosis.. Define meiosis.. Analyze function of mitosis and meiosis in cell differentiation.. Mitosis:. If a cell wants to make a . ____________. . of itself, it first must copy its DNA (part of a chromosome).. Edited By: . Ms. . Ethridge. , Ms. Myers, Ms. . Milstead. , and Ms. Palermo. Objectives. Define mitosis.. Define meiosis.. Analyze function of mitosis and meiosis in cell differentiation.. Mitosis:. If a cell wants to make a duplicate of itself, it first must copy its DNA (part of a chromosome).. Parts of the Human Cheek Cell at 40X Magnification. Can you name these parts of the Human Cheek Cell?. CELL CYCLE. D. uring Interphase DNA replicates which must occur before Mitosis can begin .. Centrioles. a single . DNA molecule complexed with histone . proteins. DNA is organized within the nucleus as chromosomes. Each chromosome is comprised of subunits called nucleosomes: DNA + proteins. Chromosome numbering/naming. R. r. Source: plant-genetics.kais.kyoto-u.ac.jp. ATGGGCACTGCCACT. A chromosome is a single DNA molecule . complexed . with histone proteins. DNA is highly compacted: DNA + histone proteins = . chromatin. Eukaryotes: organisms with a true nucleus and membrane bound organelles; usually multicellular. Animals, plants, fungi, protists (microorganisms). Eukaryotic cells replicate for growth and development . Alexey Khodjakov. Wadsworth Center. Genet. Mol. Biol. vol.22 n.4 São Paulo Dec. 1999. Karyotype of Pancreatic Cancer Cells. What do you notice that appears odd amongst these chromosomes? HINT: What should a normal karyotype look like? . Stachybotrys. . chartarum. is a potent inhibitor of human protein kinase CK2 . Samer Haidar . 1,. *, . Franziska. M . Jürgens. . 1. , Dagmar . Aichele. . 1. , Annika . Jagels. . 2. , Hans-Ulrich . General Biology. Name. ________KEY_______________________. Reproduction. All Cells come from other cells (. Remember the cell theory?. ). Asexual – Organisms formed by only one parent; offspring are identical; fast; fine for environments that don’t change frequently since each organism is a clone. Structure: pancreatic acinar cells. Identification: nucleus, nucleolus, heterochromatin. Heterochromatin. Nucleus. Nucleolus. Pancreas . 158. Pancreas . 158. 32409. Nuclei with . nucleoli. 32409.