PPT-practical lab. 3 Synthesis of salicylic acid

Theory salicylic acid is prepared from methyl salicylate by hydrolysis of ester group with aqueous alkali NaOH or KOH Salicylic acid is a monohydroxybenzoic acid a type of phenolic acid and a beta hydroxy acid This colorless crystalline organic acid is widely used in organic synthesis and functions as a plant hormone It is derived from the metabolism of . Aspirin. Used as an analgesic (pain killer) for headaches, toothaches, neuralgia (nerve pain), muscle pain and joint pain.. Also effective as a fever reducer and anti-inflammatory.. Has anticoagulant properties – prevents strokes and heart attacks.. Aspirin. perhaps most popular medicinal agent ever discovered. 30 000 000 . lb. /year sold in the US. Antipyretic (reduces fever). Anti-inflammatory (reduces . swelling suppresses prostaglandin hormone). Pharmacology I. . Discovery, Metabolism, and Industrial Applications of . ASPIRIN. Drugs. Any substance that, when absorbed into the body of a living organism, alters normal bodily function. Drugs are divided into two different groups:. Chapter 14. Aspirin. Pharmaceutical products are often developed from substance found in a plant that has been used for traditional medicine.. Aspirin is one of these products.. Salicylic acid is the active substance that helps . De Novo. Synthesis of . Purine. Nucleotides. We use for . purine. nucleotides the entire . glycine. molecule (atoms 4, 5,7), the amino nitrogen of . aspartate. (atom 1), amide nitrogen of glutamine (atoms 3, 9), components of the . ABSTRACT salicylic acid, *Corresponding Author. Mailing address: Escola de Qu Salicylic Acid Synthesis and Utilization. Kevin . McGovney. Aurion. . Farhadi. Nicholas Bean. Purpose: Synthesize Salicylic Acid Using the Kolbe-Schmitt Reaction. Kolbe-Schmitt Reaction: Was first successfully carried out in 1860 by a German chemist named Hermann Kolbe, by heating a mixture of phenol and sodium hydroxide in the presence of carbon dioxide at high pressure. . Determination of . Indomethacin. /Salicylic Acid Mixture. Objectives. Scan an absorbance spectrum using the spectrophotometer. .. Deduce the dependence of the absorption coefficient on the wavelength.. Therapeutic uses & contraindication. Aspirin . act as an analgesic, antipyretic, Anti-inflammatory also inhibit platelet aggregation & prolongs bleeding time, because of its effect on G.I.T it is contraindicated in peptic . Chemistry 1060 Laboratory. Analysis. Purity determination. Thin Layer Chromatography (TLC). Separation and identification. stationary . phase – silica gel. mobile . phase – organic solvent. Relative attraction to the two phases. When the body has met all its energy needs and the glycogen stores are full, . acetyl CoA from the breakdown of carbohydrates and fatty acids is used to synthesize new fatty acids in the cytosol.. two-carbon acetyl units are linked to form a 16-carbon fatty acid, . Theory. :. L-Cysteine is directly acetylated with acetic anhydride in the presence of a few drops of. . concentrated . sulphuric. acid to produce . acetylcysteine. and a mole of acetic acid. . The H. 3. Surface Active Agents. Done by :. Hiba. Sabah . Sura. . Alkazzaz. Nora . Zawar. introduction. Surface-active . agents . or . surfactants. are molecules and ions that are adsorbed at interfaces. Surfactants are materials that lower the surface tension (or interfacial tension) between two liquids or between a liquid and a solid. An alternative term is . Internally , although it shows antipyretic and analgesic activities, its salts and derivatives are used for these purposes.. There are two types of derivatives of SA depends upon the attack on which group takes place:.