PPT-Of mice and men – Development of a mouse model for intrahepatic cholangiocarcinoma

Targeting BAP1 mutations in intrahepatic cholangiocarcinoma The Cholangiocarcinoma Foundation March 30 2016 About Rebecca Marcus MD Clinical research fellow working under preeminent pancreatic cancer expert Dr . Associate Professor of Pediatrics and Pathology. Division of Pediatric Gastroenterology. University of North Carolina at Chapel Hill. Critical Design Issues Involved in Mouse Studies of the Intestinal Microbiota. Matthew Ramsey, PhD. Brigham and Women. ’. s Hospital. Department of Dermatology. Why study cancer in the mouse?. Protein-coding regions of the mouse and human genomes are ~85% identical. Very similar physiology. Comparative Biosciences, Inc.. 786 Lucerne Drive. Sunnyvale, CA 94085. Telephone: 408.738.9260. www.compbio.com. A TRANSLATIONAL APPROACH TO PRECLINICAL RESEARCH. Comparative Biosciences, Inc.. 20 years . Key Points. PSC is a risk factor for developing cholangiocarcinoma (CCA). Screening is controversial. Remaining in close contact and having routine visits with your healthcare team is essential to early diagnosis. CCF Grantee Webinar Series . I. 10-26-15 . Daniela Sia, PhD. Icahn . School of Medicine at Mount Sinai. Mount Sinai Liver Cancer Program . Divisions of Liver Diseases. New York, . NY. daniela.sia@mssm.edu. Problem. How do species change over time?. Hypothesis. State what will happen to each color variation of mice in both the white and brown sand environments and support why this is the case.. Materials. i. llustrated by Jennifer Gross from the original story written by . James Orchard . Halliwell. -Phillips . There once was a family of mice. There were too many mice for the mother to take care of so she sent her three oldest children to go and make a living for themselves. . Background. Of Mice and Men. was published in 1937. It tells the story of two migrant workers, George and Lennie.. The story generated many criticisms because of its use of vulgarities and how it condemned the ranch owners and their treatment of migrant and minority workers.. Offer a rodent ration containing 1216% protein and 46% fat, either in pellet or block form. Avoid commercially available seedbased diets as they predispose your mouse to obesity and nutritional defici 1557 1557 HaeRim Kim, Faiz Ur Rahman, KwangSoo Kim1,2, EunKyeung KimSangMi ChoKihoon Lee Oksung MoonYoungwon SeoWonKee YoonYoungSuk WonHoyoung KangHyoungChin and KiHoan Nam Corresponding uthorHoan Na Dr. Nandor Nagy. Developmental model organisms. Often used . model organisms. in developmental biology include the following:. Vertebrates. . Zebrafish . Danio rario. Medakafish . Oryzias latipes. . . approach. ESDO Learning Bytes 2022. Yawen Dong . Department of Surgery. HPB . Center. , Clinic . Favoriten. Vienna, Austria. Introduction . extrahepatic. Rising incidence of . intrahepatic. CCA in the past two decades.. a.. NSG Rosiglitazone maleate treated mouse. b.. NSG mouse -1 year old. c.. hSCF. mouse (. hSCF. cytokine) -1 year old. NSG- SGM3 mouse (IL-3, . hSCF. , G-MSCF) -1 year old. Extended data. Control NSG mouse. There is currently a lack of cholangiocarcinoma (CCA)-specific educational resources. that are . designed to support the adoption of ICD-11 among healthcare professionals and those involved in coding. .