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The role of side chains in substituted

pyrrole. derivatives towards . antiprolifetative. activity. F. . Mingoia. a. , . R. . . Delisi. b. , . M.Virruso. a. , . A.M. . Almerico. b. , A. . Lauria. b. Introduction. In the last years, the application of computational methodologies in medicinal chemistry field has found an amazing development. In spite of the increasing reliability of computational methodologies, not always the designed leads, once synthesized and screened, are suitable for the chosen biological target. To give another chance to these inactive compounds many structural modification could be carried on such as the introduction of side chains. As recently reported in literature, .

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The role of side chains in substituted






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