Second lecture Sept 3 2020 93 Lecture What are the basic molecules cells and tissues of the immune response Reading Immunobiology textbook Chapter 1 Basic concepts in Immunology ID: 1042373
Download Presentation The PPT/PDF document "MCB 4211 Basic Immunology" is the property of its rightful owner. Permission is granted to download and print the materials on this web site for personal, non-commercial use only, and to display it on your personal computer provided you do not modify the materials and that you retain all copyright notices contained in the materials. By downloading content from our website, you accept the terms of this agreement.
1. MCB 4211Basic Immunology Second lectureSept 3, 2020
2. 9/3 Lecture: What are the basic molecules, cells and tissues of the immune response?Reading: Immunobiology textbook Chapter 1: “Basic concepts in Immunology”A. Cells of the immune response1. hematopoiesisa. lymphoid lineageb. other cells (erythroid and myeloid lineages)c. how can these cells be identified, separated and functionally characterized?2. structure/function of cells in these lineages3. organization of cells into tissues and organs4. lymphocyte traffickingB. Major soluble components of the immune system1. antibodies 2. complement 3. cytokines
3. First, some terms…Differentiation: phenotypic changes in a cell or its behaviors Determination: changes in programming that may not yet be reflected in phenotypeStem cells: self-renewing cells that provide source material for differentiated cell populationsTotipotent stem cellPleuripotent stem cell
4. Hematopoiesis
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17. Soluble mediators of immunity (some main examples)
18.
19.
20. https://link.springer.com/article/10.1007/s00011-010-0220-6
21. Cytokines as ”immune hormones”; soluble mediators of intracellular communicationhttps://www.sinobiological.com/resource/cytokines/cytokines-definition
22. https://www.creative-biolabs.com/complement-therapeutics/membrane-attack-complex.htm
23. Tissues of the immune systemLymph nodesSpleen ThymusBone marrowPeyer’s patchesPlus there is a whole nomadic population of immune cells in almost all tissues
24.
25. Slides after this are extra/”added value”
26.
27.
28.
29.
30.
31.
32.