wwwOneTestforCancercom 1 1 Why screen for early stage cancer 2 Who should be screened 3 Why OneTest Why now 4 How accurate amp reliable is this test 5 How to order ID: 779283
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Slide1
Have 5 minutes? Scroll through to learn these 5 things:
www.OneTestforCancer.com
1
1. Why screen for early stage cancer?
2. Who should be screened?
3.
Why
OneTest
? Why now?
4. How accurate & reliable is this test?
5. How to order
OneTest
today?
Slide2Why Screen for Early Stage Cancer?
www.OneTestforCancer.com
2
Survival outcomes for screen detected cancers far exceed those of cancers diagnosed after symptoms occur (usually after cancer has spread).
Example: ~90% survive screen detected Stage 1 (confined tumor) lung cancer vs. ~5% who survive Stage 4 lung cancer (spread to other organs)
Slide3Who benefits from regular cancer screening?
www.OneTestforCancer.com
3
Anyone who is at risk for either of the top 2 causes of cancer.
Q. What are these top 2 causes?
(Answer on next slide)
Slide4www.OneTestforCancer.com
4
A. The top 2 causes of cancer:
Aging and Bad Luck
.
Among all tumor types 66% of the genetic mutations that lead to cancer come from random mutations over a lifetime; 29% from lifestyle or environment; 5% from genes inherited from Mom & Dad.
See :
https://hub.jhu.edu/2017/03/23/cancer-mutations-caused-by-random-dna-mistakes/
Slide5Why OneTest?
www.OneTestforCancer.com
5
Believed to be the world’s first blood test for the early detection of up to
5 or more potentially deadly cancers
(Lung, Liver, Pancreatic, Ovarian, Colon, and others) powered by
machine learning algorithms
build with data from tens of thousands of individuals tested
before being diagnosed
with cancer.
Slide6Your Health History
Age
Gender Smoking
history Disease history
Co
u
g
h
/S
y
m
p
t
o
m
s
Prior
diseasesFamily HistoryEtc. Etc. …
Tumor biomarkers in the blood (proteins)
:
CEA
CA
125
CYFRA
21-1
CA 19.9
AFP
P
SA
Higher scores usually followed up w/ repeat blood tests and then imaging.
Goal:
detect and remove tumors early,
before
they spread
6
Machine learning (AI) compares the pattern of
your
tumor biomarkers + health history with those of thousands of others w/ known cancer outcomes one year after getting similar test.
Detecting Early,
More Treatable Cancer
Slide7The Importance of Serial Testing
www.OneTestforCancer.com
7
Many studies have shown that measurable changes in tumor marker values can bee seen 2-3 years before diagnosis and can be an important indicator of developing disease. These studies have shown this phenomena for various types of cancer including pancreatic, ovarian, prostate among others. By monitoring tumor marker values and identifying increases in values over a fixed interval, early detection and diagnosis may offer significantly improved chances for a successful outcome.
Slide8Accuracy & Reliability
8
SE (
%)
SP (
%)
Single Time Point
(validated)
Biomarkers Alone
51.5
85.1
OneTest
(Biomarkers+ Algorithm)
82.3
80.8
Serial Testing
(expected)
85-90
85-90
Sensitivity (SE) % of true cancers currently identified
Specificity (SP) % of true non-cancers correctly identified
Based on 40,000 individuals tested up to 1 year before cancer diagnosis =
enhanced reliability for screening
Significant accuracy improvement for many cancers expected after 3+ consecutive years of testing—
Order a baseline test
today
to maximize detection power over time
Slide9Ready to Order?
9
Purchase
OneTest before Fathers Day (June 17) for
25% off
($149) but
only while supplies last
—
limited availability
Review and complete on-line Health Questionnaire and other forms at
www.OneTestforCancer.com
Take blood specimen collection kit to a doctor for blood draw and prescription (referral list available)
Test results expected in about one week for samples received after June 17