Koye A 1 Lemlemu E 2 Sabe Z 3 1 Hule Pharmacy Addis Ababa Ethiopia 2 Debre Markos University Debre Markos Ethiopia 3 CDTAfrica Addis Ababa University Ethiopia ID: 1009244
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1. Polyherbacy among people living with HIV in resource limited settings: implication for drug-herb interactions Koye A1, Lemlemu E2, Sabe Z3 1Hule Pharmacy, Addis Ababa, Ethiopia. 2Debre Markos University, Debre Markos, Ethiopia. 3CDT-Africa, Addis Ababa University, Ethiopia.PRESENTED AT THE 23RD INTERNATIONAL AIDS CONFERENCE (AIDS 2020) | 6-10 JULY 2020VariablesFrequency (%)Sex (n = 400) F214 (53.5) M186 (46.5)Use of multiple herbal medicines (n = 400) Yes344 (86%) No66 (14%)Number of herbs used (n = 400) Two26 (6.5%) Three61 (15.3%) Four87 (21.7%) Five or more226 (56.5%)Consulted health professionals (n = 400) Yes 24 (6%)) No 376 (94%)CONCLUSIONThe finding suggests that there might be risk of potential herb-herb and drug-herb interaction leading to adverse health outcomes among people living with HIV in poor settings. Providing health education about the consequences of polyherbacy will be imperative to reduce potential herb-antiretroviral medication interactions. However, further research is required to ascertain the potential herb-drug interactions and harmful health outcomes of polyherbacy.RESULTS Four hundred respondents completed the survey and all reported use of at least one form of herbal medicine. The prevalence of polyherbacy among the respondents was 86% (n = 344), with 56.5% (n = 226) taking five or more concomitant herbal preparations Being female (OR, 3.1; 95%CI, 1.4-6.68; p=0.004), having no formal education (OR, 6.5; 95%CI, 3.4-13.44; p<0.001), and low income (OR, 3.0; 95%CI, 1.54-5.33; p<0.001), were associated with use of polyherbacy. Most participants (n = 376, 94%) did not disclose the use of herbal medicine with health professionals. OBJECTIVESThe aim of this study was to determine the prevalence of polyherbacy in people living with HIV in Ethiopia and motivations for consumption of these products. METHODSA cross-sectional study was conducted using an interviewer administered survey. A sample of 412 participants living with HIV and aged 18 years or above were recruited from five primary hospitals located in Addis Ababa. Table 1: Herbal medicine use