PDF-Page 2 of 11etal Appl Biol Chem 2019 6265

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peas peanuts spices and coee beans IARC has categorized OTA as a possible human carcinogen Group oup 9 Both groups of mycotoxins may contaminate various food commodities

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Page 2 of 11etal Appl Biol Chem 2019 6265: Transcript

peas peanuts spices and coee beans IARC has categorized OTA as a possible human carcinogen Group oup 9 Both groups of mycotoxins may contaminate various food commodities including luding 1. \r\r\f-\f'\f#\f\t(\r\f\r'\f\r?...\f\t\f-\r.0\f.)\f'='2\t55B\f2.\r\f\f.\tB.\t)F\n\b\b8\t*F+@,0#G\fH'"\r6\r"\f Oncogene(2003)22,6107 ThisresearchwassupportedinpartbyNIHGrantsAR35186toI.R.andGM40313toJ.C.E.-S.T.B.T.wassupportedbyNIHBiophysicsTrainingGrantGM08293.TheX-raycoordinateshavebeendepositedintheBrookhavenProteinDataBankunder 1396BIOCHEMISTRY:CREMONA,KOWAL,ANDHORECKERPROC.N.A.S.Wehavenowobservedthatunderotherreactionconditionsfluorodinitrobenzeneiscapableofproducingamarkedincreaseintheactivityofrabbitmusclealdolase.Theacti PresentaddressSchoolofChemistryUniversityofBristolBristolBS81TSFigure1ANoncanonicalcoiled-coilpatternofhydrophobichandpolarpresiduesBzinc-fingerconsensussequenceCpeptideZiCoFigure2CDspectraforZiCowith CorrespondenceBBAggarwal3CurrentaddressMendelBiotechnologyInc21375CabotBlvdHaywardCaliforniaCA94545USAReceived24February1999revised29June1999accepted30June1999Oncogene199918649665041999StocktonPressAl 2019-2020 CatalogHRSTERM PREREQUISITESBIOL 2034FALL SPRINGBIOL 101 or BIOL 111 with a grade of C or higher or SEE CATALOGBIOL 2044FALL SPRING and SUMMER variableBIOL 203 with a grade of C or higher or ProcNatLAcadSciUSA811984issmallitcanonlybeobservedatlowcytochromeccon-centrationswhicharewithintheexperimentalrangeforthepolarographicassaybutdifficulttoattainspectrophotometri-callyThusitwasonlyrecen VOL.45,1959CHEMISTRY:HASSERODTANDVINOGRAD13studies.Hemoglobinobtainedpriortocrystallizationwasalsoemployed,andnosignificantdifferencewasfoundinthesedimentationbehaviorateitherpH7.0orpH11.0.Thefollowin VOL.53,1965BIOCHEMISTRY:GIVOLETAL.677tionofthechainbycleavageofoneormorepeptidebondsmightseriouslymodifythisinformation.Thiscouldbethecase,forexample,foraproteinthatissyn-thesizedasonepolypeptidechain acids,withprolineoftenoccupyingtheYposition.Unlike-brillarcollagens,thecollagenousdomainsoftypeIVcol-lagenshavefrequentinterruptionsoftheGly-X-Yrepeatsthatareproposedtoconferstructuralexibilitytot Correspondingauthor.Tel.:3216323411.E-mailaddresses:(J.Tytgat). ContentslistsavailableatToxiconjournalhomepage:ocate/toxicon http://dx.doi.org/10.1016/j.toxicon.2014.08.0740041-0101/2014ElsevierLtd.Al For the number of hours required for courses, and for the most up - --to - --date information, please refer to the individual school websites. * A.P. credit satisfies the requirement. ** When A.P. c DepartmentofCellBiology,LernerResearchInstitute,ClevelandClinicFoundation,Cleveland,OH44195ReceivedforpublicationSeptember21,2000.AcceptedforpublicationJuly10,2001.Thecostsofpublicationofthisarticlewe Departmentsof*MedicalBiochemistryandImmunology,Pharmacology,TherapeuticsandToxicology,Hematology,UniversityofWalesCollegeofMedicine,Cardiff,UnitedKingdom;and treatedwith2.5mMdisopropyluorophosphatefor

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