PPT-PREFORMULATION

Hygroscopicity Powder Rheology amp Compaction Properties Powders as a primary requirement for pharmaceutical dosage form. Introduction. Preformulation study is the foundation of developing robust formulation.. It can be defined as a phase of research & development process for an investigation of physical and chemical properties of new drug substance alone or in combination with other . INTRODUCTION:. Prior to nomination into full development, a candidate drug should undergo a phase traditionally called . preformulation. .. Preformulation. is the physiochemical characterization of the solid and solution properties of compounds.. Part 2. Solubility Analysis. Preformulation solubility . studies . focus . on:. Drug-solvent . systems that could occur . during the . delivery of a drug candidate. . E.g.: a drug . for oral . administration should . Prefeormulation. These studies . that . focus on . physicochemical . properties of the . new compound affect drug . performance . and development . of an efficacious . dosage . form.. Preliminary evaluation and molecular optimization.