Illusion of movement dizziness Peripheral BPPV Menieres Disease Labyrinthitis Vestibular Neuritis Causes Central Acoustic Neuroma Multiple Sclerosis Head Injury DRUGS ID: 774690
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Slide1
Phase 3B ENT
Part 2
Slide2EARS: VERTIGO - Illusion of movement dizziness
Peripheral: BPPVMeniere’s DiseaseLabyrinthitisVestibular Neuritis
Causes:
Central: Acoustic NeuromaMultiple SclerosisHead Injury
DRUGS:
Gentamicin
Metronidazole
Diuretics
Slide3EARS: VERTIGO - BPPV
Very common, any age, F>M
Most = idiopathic cause
Sx
: SHORT EPISODES OF VERTIGOWORSE IN AMSUDDEN ONSETLAST ~20-30s, RAPID RESOLUTIONPROVOKED BY HEAD MOVEMENTSNO HEARING LOSS/TINNITUSDx = clinicalo/e – DIX HALLPIKE TEST (+ve = BPPV)Mgmt = usually self limitingPromote – slowly get out of bed, alcohol and head movements EPLEY’S MANOEUVRE Meds – PROCHLORPERAZINE (antiemetic/antipsychotic)
Otoliths detach into semi-circular canals
Detached otoliths continue to move once head movement stopped
DIZZINESS = VERTIGO
Differentials?
Acute labyrinthitis, Menieres, Acoustic Neuroma, RH syndrome, otosclerosis
Slide4EARS: VERTIGO – MENIERE’S DISEASE
Increase in fluid volume (endolymph) in membranous labyrinth - aka endolymphatic hydropsProgressive distension of membranous labyrinth Unknown cause, ~40-60yrsSx: Unilateral or bilateralVERTIGO +- N&VTINNITUSHEARING LOSSSENSATION OF AURAL PRESSUREDx = clinical + audiometry Mgmt = 1) Acute attack:Best rest & reassurance, antihistamine (eg cinnarizine), prochlorperazine buccal/IV2) Prophylaxis: BETAHISTINE (decrease frequency and severity)
FLUCTUATING, EPISODIC PATTERN:
ACUTE ATTACKS
= MINS-HRS, CLUSTERS (6-11/YR)Remission of sx = vary (usually months)
MUST INFORM DVLA!!
Slide5EARS: VERTIGO – LABYRINTHITIS AND VESTIBULAR NEURITIS
Labyrinthitis
Inflammation of membranous labyrinth AND vestibular nerve
Usually follows URTIF>M, adults ~30-60yrsSx:SUDDEN, SEVERE, INCAPACITATING ROTATIONAL VERTIGONOT TRIGGERED BY MOVEMENTHEARING LOSSN&VPRECEDING URTI SXDx: clinical audiometry + o/e HINTSMgmt: SELF LIMITING (1-3wks)Antihistamine – cerazine, cyclizine Prochlorperazine Corticosteroids (eg Pred)Bed rest + oral fluidsDO NOT DRIVE!
Vestibular Neuritis
Inflammation of
VESTIBULAR NERVE ONLY
Usually follows
URTI OR REACTIVATION OF LATENT HSV
F>M, adults ~40-50yrs
Sx
:
SUDDEN, SEVERE, INCAPACITATING ROTATIONAL VERTIGO
NOT TRIGGERED BY MOVEMENT
GAIT INSTABILITY
NO HEARING LOSS!!
N&V
PRECEDING URTI SX
Dx:
clinical
audiometry + o/e HINTS
Mgmt
:
SELF LIMITING
(1-3wks)
Antihistamine –
cerazine
,
cyclizine
Prochlorperazine
Corticosteroids (
eg
Pred
)
Bed rest + oral fluids
DO NOT DRIVE!
Slide6EARS: OTALGIA – OTITIS EXTERNA
Inflammation
of
outer ear Aetiology:Infectious 90% bacterial, 10% fungal Irritants/inflammation psoriasis, dermatitis, hearing aids, ear plugs, swimming etcPresentation: Otalgia Itching ear canal erythema, oedema, exudateHearing loss +- Fever, preauricular lymphadenopathyIx – clinical diagnosis +- swab MC&SRx – a) Topical Abx or combined abx + steroid, remove canal debris + analgesia b) PO Abx if spreading + empirical use of antifungal
WATCH OUT!!...NECROTISING OTITS EXTERNA
Life-threatening!! RARE
OE extends to mastoid and temporal bones
erodes bone + cartilage
Usually P. aeruginosa or
S.aureus
Sx
: pain + oedema, fever, headache, exudate, RED FLAG = FACIAL NERVE PALSY
Signs: abscess, granulation tissue
Ix: CT/MRI
Rx: ABX
IV gentamicin/ciprofloxacin/flucloxacillin
Slide7EARS: OTALGIA - ACUTE OTITIS MEDIA
Inflammation of middle ear usually follows URTI VERY COMMON – children mainlyWinter>summerRFs: Children = young age, household smoking, craniofacial abnormality (eg cleft palate)Adults = smoking, ET dysfunction, URTI, allergies, chronic sinusitis, immunosuppression
Clinical presentation: OtalgiaFever + malaiseCoryzal sxIrritability, poor feeding, restlessnessHearing loss (conductive)
Ix: CLINICAL DIAGNOSIS Audiometry if chronic hearing loss CT/MRI – complications (eg meningitis, mastoiditis, facial nerve palsy)
Rx: Sx relief – analgesia and antipyretics = Para, NSAIDSPO ABX – Amoxicillin 5days (if pen allergic = erythromycin/clarithromycin)Recurrent AOM = ENT referral
O/E
- pyrexial, red/yellow bulging TM, red pinna, +- discharge
COMPLICATIONS:
OME, TM perforation
Infratemporal infection = labyrinthitis, mastoiditis, facial nerve palsy
Intracranial infection = meningitis, encephalitis, brain abscess
Slide8EARS: OTALGIA – OTITIS MEDIA WITH EFFUSION
AKA
GLUE EAR = collection of fluid in middle ear Due to chronic inflammation = AOMCommonly children***NB – middle ear fluid in adults SUSPICIOUS MUST exclude head/neck tumour*** Presentation:CONDUCTIVE HEARING LOSSMild intermittent otalgiaAural fullness sensation +- crackling/poppingHx of recurrent URTI, AOM, +- balance problems O/E – opaque (yellow), intact, retracted TM – no signs of inflammation or discharge, loss of light reflex, presence of bubblesIx - Audiometry, Tympanogram = flat, underlying causes excludedRx:Reassure parents self limiting within ~1yr, recurrence commonGrommet insertion (surgery) Hearing aids
Slide9EARS: MASTOIDITIS
Suppurative infection of middle ear
Infection of mastoid air cells
Inflammation of mastoid
Bony destruction
Risk Factors:
young children (6-13m), IC, cholesteatoma, AOM/OME
Infecting organisms:
Strep pneumoniae
Strep pyogenesStaph aureusPseudomonas aeurginosaH.influenzae
Clinical Presentation:OTALGIA PAIN BEHIND EARSWOLLEN, TENDER RED MASS BEHIND EARPROTRUSION OF PINNAFEVERo/e – bulging, red TM+- discharge, perforation
Ix: bloods, blood cultures, discharge culture, audiogram, skull xray +- LP, CT/MRI
Mgmt: IV abx – 3rd gen cephalosporin 1-2 daysPara, NSAIDOral abx 1-2wksSurgery – mastoidectomy
Complications:Hearing loss, osteomyelitis, subperiosteal abscess, CN palsies (V, VI, VII), intracranial spread
Slide10NOSE (AND FACE): SINUSITIS
Acute = <4wksUsually viral causeSx: Non-resolving URTI sx >1wkFacial tendernessFeeling of facial pressure – worse on bending forwardsDecreased sense of smellRx: Antipyretic – ParacetamolIntranasal decongestantNasal douching + warm face packs**ABX if severe/prolonged**Completely resolves
Sinusitis = inflammation of membranous lining of one or more sinuses
Risk Factors:
URTIAllergic rhinitisAsthmaImmunocompromisedDental ProblemsChurg-StraussWegner’s
Chronic = >12wksOften assoc with nasal polypsSx: Dull ache on palpationNasal purulenceLoss of smell Rx: Nasal corticosteroids (eg beclomethasone)
Complications:
Orbital cellulitis
Meningitis
Osteomyelitis
Cavernous venous thrombosis
Intracranial abscess
Slide11NOSE (AND FACE): BELL’S PALSY
CN VII controls muscles of faceACUTE, UNILATERAL, IDIOPATHIC FACIAL NERVE PARALYSISAny age, peak 20-40yrsLMN PALSY = FOREHEAD AFFECTED Sx: vary mild - severeFacial sagging with weak muscles of facial expressionDrooping eyelid Drooping corner of mouthLoss of nasolabial foldHyperacusis Dry mouth, altered tasteDecreased tear productionDx = clinical Rx - Prednisolone PO 10 days within 72 hours - Artificial tears Prognosis – commonly spontaneous resolution
RAMSAY HUNT SYNDROME
Varicella zoster LMN facial nerve palsy
Peripheral facial neuropathy +
erythematous rash/vesicles on ipsilateral ear (+- hard palate, ant 2/3rds tongue)
Sx
– PAIN PROMINENT, HEARING LOSS +
sx
of CNVII palsy
Rx:
Acyclovir within 72hours
Slide12THROAT: SORE THROAT
Pharyngitis Aetiology = viral/bacterial (strep pyogenes - GABS)Presents: FeverOdynophagiaURTI Sx - cough, rhinorrhoea, headache, malaise+- hoarse voice GABS = SCARLET FEVER red, punctate skin eruption, strawberry tongue, flushed faceIx – only if sx persist Rx – reassure self-limiting (~1wk), antipyretics + fluids
Laryngitis
Inflammation of vocal cords and larynx
Acute <3wks
bacterial/viral/fungal infection
Chronic >=3weeks
reflux, asthma, smoking, trauma, meds, AI disease
Sx
:
Fever/malaise
Hoarse voice
Ant neck pain
Dysphagia
Globus (lump in throat)
Ix:
Laryngoscopy,
bloods, sputum culture, laryngeal swab,
xray
neck
Rx:
Acute = self limiting
vocal hygiene +-
abx
(if purulent sputum or IC)
Chronic = vocal hygiene + voice therapy
Slide13THROAT: SORE THROAT - TONSILLITIS
ANY AGE – commonly children 5-14yrs or young adults 15-25yrs
Causative Organisms:
GROUP A STREP = STREP PYOGENESStaph, Moraxella catarrhalis, Haemophilus influenzae, Mycoplasma
Clinical Presentation:Sx:SORE THROAT >= 48 HRSHIGH GRADE FEVERODYNOPHAGIAHEADAHCELOSS OF VOICE/CHANGESPREFERRED OTALGIAADBO PAINSigns:ERYTHEMATOUS THROATSWOLLEN, COATED TONSILSSWOLLEN REGIONAL LNS
Ix:
clinical dx +- bloods (FBC, CRP), throat swab
Management:Reassurance RestFluidsAntipyretic - paracetamolABX or no ABX?! CENTOR CRITERIA**>= 3 = ABX**PHENOXYMETHYLPENICILLIN PO 10 DAYSSurgery = TONSILLECTOMY
Complications:
peritonsillar abscess, acute OM, RF, glomerulonephritis, scarlet fever, sleep apnoea
Slide14THROAT: SORE THROAT – GLANDULAR FEVER
INFECTIOUS MONONUCLEOSIS
caused by EBV
Usually adolescents
Clinical Presentation:
Sx
:
Low-grade feverFatigue/Malaise may persist for months post acute infection resolutionSore throatNausea/AnorexiaSigns:Tonsillar enlargement exudatePalatal petechiaeFine, macular non-pruritic rash Lymphadenopathy LATER - hepatosplenomegaly
Associated with Burkitt’s lymphoma, B-cell lymphoma, undifferentiated carcinomas
Ix:
IM heterophil antibodies
MONOSPOT TESTEBV specific antibodiesViral capsid antigensEBV nuclear antigenBloods – FBC, ESR, LFTsThroat swab
Management:SUPPORTIVE:PARABED RESTFLUIDS PO/IV
AVOID AMOXICILLIN IN ANYONE WITH SUSPECTED IM
WIDESPREAD ITCHY MACULOPAPULAR RASH
WATCH OUT!!!
AVOID CONTACT SPORT 8WKS POST IM…
AT RISK OF SPLENIC RUPTURE
Slide15THROAT: SORE THROAT - QUINSY
Pus trapped between tonsillar capsule and lateral pharyngeal wallUsually complication of acute tonsillitis or glandular fever Most commonly teensCausative organisms:Strep pyogenesStaph aureusHaemophilus influenzaeSx:SEVERE SORE THROATFEVER/MALAISEDROOLING SALIVAFOUL-SMELLING BREATHOYDNOPHAGIATRISMUS due to pterygoid muscle spasmALTERED VOICE QUALITYOTALGIANECK STIFFNESS
Signs: Cervical lymphadenopathyUvula deviated AWAY from lesionUnilateral tonsil bulgingDx: clinical Management:AnalgesiaIV fluidsIV abx benzylpenicillin/amoxicillin Surgery NEEDLE ASPIRATION or INCISION AND DRAINAGEQuinsy tonsillectomy (6wks post quinsy)
Slide16THROAT: SALIVARY GLAND SWELLINGS
PAROTITIS:
Viral/bacterial
Presents:
Painful, tender swelling near ear
Dry mouth
Difficulty opening mouth
Pain on eating
Fever
Foul taste
N.B MUMPS = bilateral swelling >=1 + low grade pyrexia
Ix – Bloods, viral serology, salivary antibody testing, pus swab cultures,
USS, sialography
, CT/MRI
Rx – MUMPS = self-limiting
Suppurative =
abx
+- incision and drainage
Slide17THROAT: SALIVARY GLAND SWELLINGS
ObstructionStones most common causeSubmandibular or parotid gland usuallySx: colicky pain + swelling at meal timesIx: USS, sialography (contrast + xray)Rx: may pass spontaneously – hydration, warm compress, gland massage Surgical removal
Sialadenosis
Generalised non-inflammatory,
painless bilateral swelling of gland
(usually parotid)
Caused by
hypertrophy
of
acinar
component
ASSOCIATED WITH SYSTEMIC DISEASE
– Sjogren's, sarcoid, malnutrition - anorexia, endocrine disorders
Ix:
Sialography
– sialectasis (cystic dilatation of ducts), biopsy, autoantibodies,
Rx:
Pilocarpine
- for hyposalivation, ? refer to
rheumatology