Predictor or Result of Poor Outcome Ron Donelson MD MS SelfCare First LLC Red Flags Red flags Indicators of underlying insidious pathology spine fracture tumor infx Main amp Burton 2000 Nicholas et al 2011 ID: 504938
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Yellow Flags and Exercise Treatment:
Predictor or Result of Poor Outcome?
Ron Donelson, MD, MS
SelfCare First, LLCSlide2
Red Flags
Red flagsIndicators
of
underlying insidious pathology: spine fracture, tumor, infx
Main & Burton, 2000; Nicholas, et al, 2011
Orange flags
Psychiatric sxs and disorders: Axis I and II disorders
Blue FlagsBeliefs about workplace (lack of support from supervisors, co-workers); belief that return will cause injury
Black FlagsFamily and system factors (insurance claim conflicts, overly solicitous family or health care provider)
Others
Yellow flags
(Kendall 1997)Unhelpful beliefs about pain/emotional responses/pain behavior & coping
Yellow FlagsSlide3
Yellow Flags
Psychological and social factors that increase the likelihood of long-term disability and work loss in persons with low back pain.But not always.Slide4
Yellow flags: “Obstacles to Recovery”
More questions than answers..
Some
YFs
are indeed
obstacles to recovery
that need attention.But some aren’t. They’re false-positives.Q#1: How do we know which
are which?Slide5
WARNING: Diagnosing low back pain means sorting through many false-
positives or misleading findingsUnreliable exam findings: asymmetries, tenderness
Referred
tenderness: SIJ,
myofascial trigger points,
pyriformis, trochanteric bursitis
Imaging: HNPs and DDD in symptomaticsQ#2: Which findings are relevant
? False-positives? Slide6
Q#3: Why are
YFs sorelevant with LBP?Why aren’t they also prominent
with abdominal, chest, shoulder, hip or knee
pain?
Or
even spinal fractures,
HNPs and sciatica? Slide7
Would making a
patho-mechanical diagnosis (DP?) early make a difference?Would making a diagnosis
early make a difference?
Q#4: Are
YFs
only relevant when
the underlying diagnosis is uncertain?Slide8
Q#5: Do
YFs cause pain to persist or does persisting pain cause YFs to develop?
OR BOTH?Slide9
Do they ever co-exist?
If so, which prevails? Dir. pref. and centralization are found in most LBP patients and predict an excellent prognosis for recovery.Consider:
In contrast,
YFs
are considered to be possible obstacles to recovery.Slide10
Centralization and Fear-Avoidance Beliefs
Centralizers have lower involvement of psychological factors.The presence of yellow flags (elevated fear-avoidance beliefs) was associated with non-centralization.Christiansen D, et al. Pain responses in
rpted
end-range spinal
mvts and
psycho’l factors in sick-listed pts with LBP: is there an association? J
Rehabil Med. 2009. Slide11
Centralization and Fear-Avoidance
Fear-avoidance was equally present in centralizers and non-centralizers.Even with high fear, centralization still predicted a good outcome in the majority. So in centralizers, addressing fear-avoidance beliefs is unnecessary.If centralization is not present, but high levels of fear are, formal cognitive behavioral techniques should be used to address these beliefs.
Werneke
M, Hart D, George S. Clinical outcomes for patients classified by fear-avoidance beliefs and centralization phenomenon. Arch Phys Med Rehab. 2009Slide12
Yellow flags were common:
non-organic physical signs, overt pain behaviors, depressive symptoms, somatization, fear-avoidance beliefs, and perceived disability.When treated with directional exercises, the outcomes at one year were so positive, the yellow flags were
non-predictors of outcome.
Werneke
M, Hart DL. Centralization phenomenon as a prognostic factor for chronic low back pain and disability. Spine 2001
In 223 acute back and neck pain centralizers with a DP
:Slide13
In
71 patients with a dir. pref.:Both
Beck Depression Inventory and
Interference
W
ith W
ork and Leisure A
ctivity significantly improved after just two weeks of matching directional exercises only.
It is futile to conduct prognostic studies without including baseline centralization/DP determination.
Long A, Donelson R, Fung T. Does it matter which exercise? A randomized controlled trial of exercise for low back pain. Spine 2004Slide14
All studies of LBP outcome predictors need to include baseline determination of the presence or absence of both:
Yellow FlagsDirectional PreferenceSlide15
On the other hand…..
with directional preference so common and so strongly predictive of good outcomes with appropriate directional treatment….How important is baselineYellow Flag determination?Yellow flags may only have relevance if MDT evaluation and treatment fail….
Along with imaging, injections, and surgeries
.Slide16
As high quality MDT becomes the
front-line of care for painful cervicaland lumbar disorders….yellow flags, imaging, medications, injections, and surgeries need only be considerations for a small percentage of patients. Slide17
17
a non-specific symptom that once was attributed to non-physical issues: immorality,
lack of faith, etc.
But innovative diagnostic technologies:
microscope
microbes infection,
and sensitivities to antibiotics.FEVER
> 60% of health care budget
14%.Slide18
Prevalence of dir. pref. & centralization:
Donelson (Spine 1990) 84-89 %Sufka (JOSPT, 1998) 60-83 %Werneke (Spine, 1999) 77 %
Karas (Phys. Ther. 1997) 73 %
Donelson (Spine 1991, ISSLS 1991) 58 %
Delitto (Phys. Ther. 1993) 61 %
Erhard (Phys. Ther. 1995) 55 %Kopp (CORR, 1986) 52 %
Long (Spine, 1995) 43 %Donelson (Spine ,1997) 49 %Laslett (Spine Jrnl, 2005) 32 %
Acute
Chronic
How common is dir. pref.: a reducible derangement?
Acute, Chronic
Axial pain, SciaticaDegenerative discPseudo-claudicationSpondysSlide19
Chronic: 50% reducible
Acute: 70-89% reducible derangements
Many became irreducible chronics
Misdiagnosed
Ineffective, costly, avoidable care
LOST window of opportunity
Undiscovered
while
acute and
subacute
.
Ineffective, costly, avoidable care
Misdiagnosed
QTF: “inaccurate dxs which are then further confounded with each succeeding step in care”
Missed window of opportunity
Yellow Flags
Yellow flags, MRIs, medications, injections, surgeriesSlide20
After TESIs, MDT exam repeated
69 non-centralizers
van
Helvoirt
H, et. al.
Transforaminal
epidural steroid injections followed by Mechanical Diagnosis and Therapy to prevent surgery for lumbar disc herniation. Pain Medicine. 2014.16%
16%22%
46%Centralizers
38% Non-Centralizers
underwent TESIs
.Yellow Flags?Slide21
Recurrences: Benign or Worsening?
Survey of 589 respondents with LBP: 73% had prior episodes; 54% had 10 or more and 19% had more than 50 episodes. 61% had recent episodes worse than prior ones;
21% were worse in all 5 surveyed domains.
Conclusion: Recurrences often worsen
over time.
Donelson R, McIntosh G, Hamilton H. Is it time to rethink the typical course
of low back pain? Physical Medicine & Rehabilitation Journal. 2012. Slide22
Recurrences often progressively worsen and last longer….
Until recovery finally stops……and pain becomes constant and chronic?Are worsening recurrences acommon a pathway to chronicity
? Slide23
Ques: If dir. pref. is found in 70-90% of
acute LBP, predicts excellentoutcomes and prevents recurrences using directional exercises, what is the biggest obstacle to recovery?Answer: Depriving patients ofa good MDT assessment. A far more significant obstacle
than the presence of yellow flags?Slide24
Chronic: 50% reducible
Acute: 70-89% reducible derangements
Chronic: 30%(?) now
irreducible
All preventable!
Accurate mechanical diagnosis when acute or subacuteSlide25
So are YFs the biggest obstacle to recovery from LBP and neck pain?
Not if their influence disappears in the presence of a dir. pref.If 70-89% of acute LBP have a dir. pref., then YFs are only relevant in the other 11-30%.Slide26
To minimize the effects of
Yellow Flags, LBP clinical
g
uidelines recommend
reassurance of likely recover…..
based on the positive natural history.
What could possibly be more reassuring than showing a patient that their pain is reversible and that they can eliminate it
themselves?Is that why Yellow Flags disappearas obstacles to recovery with Dir. Pref.? Slide27
Red Flags
Yellow Flags
Red
flags
Indicators
of underlying insidious pathology: spine fracture, tumor, infx
Main & Burton, 2000; Nicholas, et al, 2011
Yellow flags (Kendall 1997)Unhelpful beliefs about pain /emotional responses / pain behavior & copingOrange flags
Psychiatric sxs and disorders: Axis I and II disordersBlue FlagsBeliefs about
workplace (lack of support from supervisors, co-workers; belief that return will cause injuryBlack Flags
Family and system factors (insurance claim conflicts), overly solicitous family or health care provider
Green FlagDirectional preference / centralizationSlide28