Infectious Disease Cytomegalovirus IgG IgM IgG Avidity - PDF document

maternal primary infection. Intrauterine transmission of CMV is to primary infections contracted during pregnancy (2% vs laboratory techniques are the sole means of diagnosing acute serology line has been developed to solve diagnostic ambiguities. Sensitive and quantitative CMV IgM, with highly specic and quantitative CMV IgG, both complemented by CMV avidity determination in a fully automated LIAISONassay environment, will allow the laboratory to report clear u @umleru Molid (pp28,u Lalel:u Method:u Quantitativeu Mampleu 5ighu Leagentu Owo-pointu Mample AcuteInfectionPast InfectionIgGIgMAntibody titresTimeIgG positiveIgM positiveLow Avidity IgG positiveIgM positiveHigh Avidity IgG positiveIgM negative/positiveHigh Avidity IgGIgMAvidityDiagnosisNegativeNegativeNo infectionPositivePositiveLowPossiblePositivePositiveHighReactivation/Past infectionPositiveNegativePast infectionM0870004274 12346 04/13 AVAILABLE ON SYSTEMS Infectious Disease Rubella VirusIgG, IgMTotal automation for accurate differential diagnosis FOR OUTSIDE THE US AND CANADA ONLY in developed countries, rubella continues to occur because help identify women who are susceptible to rubella during u @umleru Molidu Lalel:u Method:u Quantitativeu Mampleu 5ighu Leferenv LQ)6-1-94u Leagentu Owo-pointu Mample Upper respiratory tractViraemiaInfection Virus sheddingIgGIgMLymphadenopathyArthralgiaOnset of feverTime (daysRas Antibody titres IgGIgMDiagnosisNegativeNegativeNo infectionPositiveNegativePast infectionPositivePositiveAcute infection / Past infection(long lasting IgM)M0870004276 12348 04/13 AVAILABLE ON SYSTEMS Infectious Disease Herpes Simplex VirusHSV-1/2 IgG, HSV-2 IgG,HSV-1 IgG, HSV-1/2 IgMTotal automation for accurate differential diagnosis FOR OUTSIDE THE US AND CANADA ONLY last trimester of pregnancy. Since most individuals infected u @umleru Molidu Lalel:u Method:u Qualitativeu Mampleu 5ighu Leagentu Owo-pointu Mample HSV IgHSV IgAcutePrimaryInfectionPast Infection/reactivationTimeAntibody titres M0870004277 12349 04/13 HSV-1/2 IgGHSV-2 IgG HSV-1 IgGHSV-2 IgG AVAILABLE ON SYSTEMS FOR OUTSIDE THE US AND CANADA ONLYBiotrin quality. Total automation Condence in Your ResultsParvovirus B19 is an erythrovirus that has been associated to a growing number of clinical presentations, the two most important being Fifth Disease in children and fetal complications during pregnancy. Observed in outbreaks, parvovirus B19 is highly contagious and presents children, especially in the age group 4-11 with fever, muscle pains, arthralgia and a characteristic facial rash. In pregnancy, infection of the fetus during the rst 28 weeks of term, can lead to cardiac failure, spontaneous abortion, or fetal hydrops. It is estimated that every year, in a population such as that of the European Union, there are more than 1.2 million pregnant women who are at risk of infection. Screening for IgG antibodies to parvovirus B19 allows the pregnant woman to know whether she is immune to infection. In parallel, the detection of IgM antibodies will alert the clinician to a current parvovirus B19 infection.DiaSorin has collaborated with Biotrin International (Dublin, Ireland) to exclusive antigen expression system in baculovirus, and unique assay features such as the direct IgM capture system, Biotrin has been the reference assay and market leader in parvovirus B19 diagnostics for over 10 years. Laboratories and clinicians can now benet from all the features of the Biotrin EIA kits, but with the added technological Consequently, it is important to identify the Parvovirus B19 antibody Main Features of LIAISON•AOvncfs•ATpm@e)fypsfttfe•AMbcfm:•ANfuipe:•ARvbm@ubu@wf•ATbnpmfFlexibility enables quick and accurate results•AI@hiuispvhpvu•ATxp.pp@ousfdbm@csbu@po•ARvbou@ubu@wf•AE@sfdudbpuvsf•ATbnpmfOrdering InformationAVAILABLE ON SYSTEMS LIAISON® Biotrin Parvovirus B19 IgG, IgM Antibody titresT@nf Past infectionDiasorin Ireland Ltd.Unit 13/14 Holly Avenuewww.diasorin.com Infectious Disease CytomegalovirusIgG, IgM, IgG Avidity IITotal automation for accurate stagingof infection during pregnancy FOR OUTSIDE THE US AND CANADA ONLY Condence in Your ResultsToxoplasma gondii IgG, IgM, IgG Avidity Toxoplasma assay panel is the solution Toxoplasma infection can cause severe damage in cases of determine if the mother has been infected by Toxoplasma to discriminate between chronic and recent infections. The presence of Toxoplasma-specic IgM in serum is an indicator of recent infection, but often IgM persists and may be detected diagnosis dating the infection more precisely. A high Avidity Index excludes recent Toxoplasma infection within the last four months. Therefore a high IgG Avidity Index during the • Number• SolidToxoplasma (p30,• Label:• Method:• Quantitative• Sample• High• Referenced• Reagent• Two-point• SampleToxoToxoToxoAvidityToxoToxoToxoAvidityMain Features of LIAISONToxoplasma Ordering informationFlexibility enables quick and accurate results AcuteInfectionPastInfectionIgMIgGAntibody titresTimeIgG positiveIgM positiveLow Avidity IgG positiveIgM negative/positiveHigh Avidity AvidityPositivePositivePossiblePositivePositivePast infectionPositivePast infection Product availability subject to required regulatory approval.ViaTel.www.diasorin.comAVAILABLE ON SYSTEMS Infectious Disease Toxoplasma gondiiIgG, IgM, IgG AvidityTotal automation for accurate staging of infection during pregnancy FOR OUTSIDE THE US AND CANADA ONLY